Ehrlich tumor stimulates extramedullar hematopoiesis in mice without secreting identifiable colony-stimulating factors and without engagement of host T cells

Experimental Hematology

Volumn 27, Issue 12, 1999, Pages 1757-1767

  De Morales, José Ruiz ^a   Vélez, Desireé ^a   Subiza, José Luis ^a  

^a HOSPITAL CLÍNICO SAN CARLOS   (Spain)

Author keywords

Cytokine; Extramedullar hematopoiesis; Immunodeficient mice; Tumor

Indexed keywords

COLONY STIMULATING FACTOR; COLONY STIMULATING FACTOR 1; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1ALPHA; LEUKEMIA INHIBITORY FACTOR; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA; WHEAT GERM AGGLUTININ;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; EHRLICH ASCITES TUMOR CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRAMEDULLARY HEMATOPOIESIS; IMMUNE DEFICIENCY; IN VITRO STUDY; MALE; MOUSE; NEUTROPHILIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLENOMEGALY; T LYMPHOCYTE; THROMBOCYTOSIS; TUMOR CELL LINE; TUMOR GROWTH;

ANIMALS; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIESIS, EXTRAMEDULLARY; MALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, NUDE; T-LYMPHOCYTES;

TRITICUM AESTIVUM;

EID: 0345533984     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(99)00119-8     Document Type: Article

References (61)

1. Di Persio J.F., Brennan J.K., Marshall A., Lichtman A., Speiser B.L. Human cell lines that elaborate colony-stimulating activity for the marrow cells of man and other species. Blood. 51:1978;507.
2. Gabrilove J., Welte K., Lu L., Castro-Malaspina H., Moore M. Constitutive production of leukemia differentiation, colony-stimulating, erythroid burst-promoting and pluripoietic factors by a human hepatoma cell line. characterization of the leukemia differentiation factor Blood. 66:1985;407.
3. Mano H., Nishida J., Usuki K., Maru Y., Kobayashi Y., Hirai H., Okabe T., Urabe A., Takaku F. Constitutive expression of the granulocyte-macrophage colony-stimulating gene in human solid tumors. Jpn J Cancer Res. 78:1987;1041.
4. Lylly M.B., Devlin P.E., Devlin J.J., Rado T.A. Production of granulocyte colony-stimulating factor by a human melanoma cell line. Exp Hematol. 15:1987;966.
5. Baldwin G.C., Gasson J.C., Kaufman S.E., Quan S.G., Williams R.E., Abalos B., Gaztar A.F., Golde D.W., Di Persio J. Non hematopoietic tumor cells express functional GM-CSF receptors. Blood. 73:1989;1033.
6. Turner A.M., Zsebo K.M., Martin F., Jakobsen F.W., Bennet L.G., Broudy V.C. Non-hematopoietic tumor cell lines express stem cell factor and display c-kit receptors. Blood. 80:1992;374.
7. Aaronson S. Growth factors and cancer. Science. 254:1991;1146.
8. Ross H.J., Sato N., Ueyama Y., Koeffler P. Cytokine messenger RNA stability is enhanced in tumor cells. Blood. 77:1991;1787.
9. Sporn M.B., Roberts A.D. Autocrine growth factors and cancer. Nature. 313:1985;745.
10. Dedhar S., Gaboury L., Galloway P., Eaves C. Human granulocyte-macrophage colony stimulating factor is a growth factor on a variety of cell types of non hematopoietic origin. Proc Natl Acad Sci U S A. 90:1988;3539.
11. Yamasita Y., Nara N., Aoki N. Antiproliferative and differentiative effect of granulocyte-macrophage colony-stimulating factor on a variant human small cell lung cancer cell line. Cancer Res. 49:1989;5334.
12. Colombo M., Ferrari G., Stoppacciaro A., Parenza M., Rodolfo M., Mavilio F., Parmiani G. Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo. J Exp Med. 173:1991;889.
13. Dranoff G., Jaffe E., Lazeuby A., Golumbek P., Levitsky H., Brose K., Jackson V., Hamada H., Pardoll A., Mulligan R.C. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific and long lasting antitumor immunity. Proc Natl Acad Sci U S A. 90:1993;3539.
14. Hall T., Staszewski H. Paraneoplastic syndromes. Semin Oncol. 24:1997;329.
15. Lee M., Kahushansky K., Judkins S., Lottsfeldt J., Waheed A., Shadduck R. Mechanisms of tumor-induced neutrophilia. constitutive production of colony-stimulating factors and their synergistic actions Blood. 74:1989;115.
16. Schmitter D., Lauber B., Fagg B., Stahel R.A. Hematopoietic growth factors secreted by seven human pleural mesothelioma cell lines. interleukin 6 as a common feature Int J Cancer. 51:1992;296.
17. Yoneda T., Aufdemorte T., Nishimura R., Nishikawa N., Sakuda M., Alsina M., Chavez J., Mundy G. Occurrence of hypercalcemia and leukocytosis with cachexia in a human squamous cell carcinoma of the maxilla in athymic nude mice. a novel experimental model of three concomitant paraneoplastic syndromes J Clin Oncol. 9:1991;468.
18. 2. Cancer Res. 48:1988;6826.
19. Subiza J.L., Viñuela J., Rodriguez R., Gil J., Figueredo A., De la Concha E.G. Development of splenic natural supressor (NS) cells in Ehrlich tumor-bearing mice. Int J Cancer. 44:1989;307.
20. Maier T., Holda J.H., Claman H.N. Murine graft-versus-host disease across minor barriers. immunosuppressive aspects of natural suppressor cells Immunol Rev. 88:1985;87.
21. Burlington H., Cronkite E.P., Heldman B., Pappas N., Shadduck R.K. Tumor-induced granulopoiesis unrelated to colony-stimulating factor. Blood. 62:1983;693.
22. Ikeda K., Motoyoshi K., Ishizaka Y., Hatake K., Kajigaya S., Saito M., Miura Y. Human colony-stimulating activity-producing tumor. production of very low mouse-active colony-stimulating activity and induction of marked granulocytosis in mice Cancer Res. 45:1985;4144.
23. Sakata T., Iwagami S., Tsuruta Y., Teraoka H., Suzuki S., Suzuki R. Role of colony-stimulating factor-1 in macrophage activation in tumor-bearing mice. J Immunol. 149:1992;4002.
24. Tartour E., Gey A., Sastre-Garau X., Pannetier C., Mosseri V., Kourilsky P., Fridman W.H. Analysis of interleukin 6 expression in cervical neoplasia using a quantitative polymerase chain reaction. evidence for enhanced interleukin 6 expression in invasive carcinoma Cancer Res. 54:1994;6243.
25. Viñuela J.E., Rodríguez R., Gil J., Coll J., De la Concha E.G., Subiza J.L. Antigen shedding vs. development of natural suppressor cells as mechanism of tumor escape in mice bearing Ehrlich tumor. Int J Cancer. 47:1991;86.
26. Tsuchiya Y., Igarashi M., Suzuki R., Kumagai K. Production of colony-stimulating factor by tumor cells and the factor-mediated induction of suppressor cells. J Immunol. 141:1988;699.
27. Fu Y., Watson G., Jimenez J., Wang Y., Lopez D. Expansion of immunoregulatory macrophages by granulocyte-macrophage colony-stimulating factor derived from a murine mammary tumor. Cancer Res. 50:1990;227.
28. Young M.R.L., Wright M.A. Myelopoiesis-associated immune suppressor cells in mice bearing metastatic Lewis lung carcinoma tumors. interferon-γ plus TNF-α synergistically reduce immune suppressor and tumor growth-promoting activities of bone marrow cells and diminish tumor recurrence and metastasis Cancer Res. 52:1992;6335.
29. Yamazaki H., Nitta K., Umezawa H. Immunosuppression induced with cell-free fluid of Ehrlich carcinoma ascites and its fractions. Gann. 64:1973;83.
30. Tomida M., Yamamoto-Yamaguchi Y., Hozumi M. Purification of a factor inducing differentiation of mouse myeloid leukemic M1 cells from conditioned medium of mouse fibroblast L929 cells. J Biol Chem. 259:1984;10978.
31. Angulo I., Rodriguez R., Garcia B., Medina M., Navarro J., Subiza J.L. Involvement of nitric oxide in bone marrow-derived natural suppressor activity. J Immunol. 155:1995;15.
32. Roberts A.W., Foote S., Alexander W.S., Scott C., Robb L., Metcalf D. Genetic influences determining progenitor cell mobilization and leukocytosis induced by granulocyte colony stimulating factor. Blood. 89:1997;2736.
33. Gil J., Alvarez R., Viñuela J.E., Ruiz de Morales J.G., Bustos A., De la Concha E.G., Subiza J.L. Inhibition of in vivo tumor growth by a monoclonal IgM antibody recognizing tumor cell surface carbohydrates. Cancer Res. 50:1990;7301.
34. Chiu C., Lee F. IL-6 is a differentiation factor for M1 and WEHI-3B myeloid leukemic cells. J Immunol. 142:1989;1909.
35. Handel-Fernandez M., Cheng X., Herbert L., Lopez D. Down-regulation of IL12, not a shift from a T helper-1 to a T helper-2 phenotype, is responsible for impaired IFN-γ production in mammary tumor-bearing mice. J Immunol. 158:1997;280.
36. Metcalf D., Nicola N., Gough N., Elliot M., Mcarthur G., Li M. Synergistic suppression. anomalous inhibition of the proliferation of factor-dependent hemopoietic cells by combination of two colony-stimulating factors Proc Natl Acad Sci U S A. 89:1992;2819.
37. Demetri G., Ernst T., Pratt E., Zenzie B., Rheinwald J., Griffin J. Expression of ras oncogenes in cultured human cells alters the transcriptional and posttranscriptional regulation of cytokine genes. J Clin Invest. 86:1990;1261.
38. Mattei S., Colombo M., Meleni C., Silvani A., Parmiani G., Herlyn M. Expression of cytokine/growth factors and their receptor in human melanoma and melanocytes. Int J Cancer. 56:1994;853.
39. Sakai N., Kubota M., Shikita M., Yakota M., Ando K. Intraclonal diversity of fibrosarcoma cells for the production of macrophage colony stimulating factor and granulocyte colony stimulating factor. J Cell Physiol. 133:1987;400.
40. Pekarek L, Weichselbaum R, Beckett M, Nachman J, Schreiber H (1993) Footprinting of individual tumors and their variants by constitutive cytokine expression patterns. Cancer Res 53:1978.
41. Armstrong C., Botella R., Galloway T., Murray N., Kramp J., Sung Song I., Ansel J. Antitumor effects of granulocyte-macrophage colony-stimulating factor production by melanoma cells. Cancer Res. 56:1996;2191.
42. Yamazaki H., Nitta K., Umezawa H. Immunosuppression induced with cell-free fluid of Ehrlich carcinoma ascites and its fractions. Gann. 64:1973;83.
43. Matsubara S., Suzuki M., Makanura M., Ishida N. Isolation of an inhibitor of type II interferon from tumor ascites fluids. Cancer Res. 40:1980;2534.
44. Sugiura K., Inaba M., Ogata H., Yasumizu R., Inaba K., Good R.A., Ikehara S. Wheat germ agglutinin-positive cells in a stem cell-enriched fraction of mouse bone marrow have potent natural suppressor activity. Proc Natl Acad Sci U S A. 85:1988;4824.
45. Lord B.I., Molineaux G., Pojda Z., Souza L.M., Mermod J.J., Dexter T.M. Myeloid cell kinetics in mice treated with recombinant interleukin-3, granulocyte colony stimulating factor (CSF) or granulocyte macrophage CSF in vivo. Blood. 77:1991;2154.
46. McNiece I.K., Stewart F.M., Deacon D.M., Quesenberry P.J. Synergistic interactions between hematopoietic growth factors as detected by in vitro mouse bone marrow colony formation. Exp Hematol. 16:1988;383.
47. Arai K., Lee F., Miyajima A., Miyatake S., Arai N., Yokota T. Cytokines. coordinators of immune and inflammatory responses Annu Rev Biochem. 59:1990;783.
48. Lai Y., Heslan J., Poppema S., Elliott J., Mossmann T. Continuous administration of IL-13 to mice induces extramedullary hemopoiesis and monocytosis. J Immunol. 156:1996;3166.
49. Ohno H., Ogawa M., Nishikawa S., Hayashi S., Kunisada T., Nishikawa S. Conditions required for myelopoiesis in murine spleen. Immunol Lett. 35:1993;197.
50. Nishinakamura R., Miyajima A., Mee P.J., Tybulewicz L.J., Murray R. Hematopoiesis in mice lacking the entire GM-CSF/IL-3/IL-5 functions. Blood. 88:1996;2458.
51. Smith T.C., Levinson C. Ehrlich ascitic tumor cell surface labeling and kinetics of glycocalix release. J Supramol Struct. 12:1979;115.
52. Luo J.C., Yamaguchi S., Shinkai A., Shitara K., Shibuya M. Significant expression of vascular endothelial growth factor/vascular permeability factor in mouse ascites tumors. Cancer Res. 28:1998;2652.
53. Real A., Guenechea G., Bueren J.A., Maganto G. Radioprotection mediated by the haemopoietic stimulation conferred by AM5. a protein-associated polysaccharide Int J Radiat Biol. 62:1992;65.
54. Tateishi T., Ohno N., Adachi Y., Yadomae T. Increases in hematopoietic responses caused by beta-glucans in mice. Biosci Biotechnol Biochem. 61:1997;1548.
55. Subiza J.L., Gil J., Rodríguez R., Ruiz de Morales J.G., Viñuela J.E., De la Concha E.G. Tumor cytostasis mediated by a monoclonal IgM antibody promoting adhesion between macrophages and tumor cells. J Immunol. 148:1992;2636.
56. Kelm S., Schauer R., Crocker P.R. The sialoadhesins-a family of sialic acid-dependent cellular recognition molecules within the immunoglobulin superfamily. Glycoconjugate J. 13:1996;913.
57. Medina M., Vélez D., Asenjo J.A., Egea G., Real F.X., Gil J., Subiza J.L. Human colon adenocarcinomas express a MUC1-associated novel carbohydrate epitope on core mucin glycans defined by a monoclonal antibody (A10) raised against murine Ehrlich tumor cells. Cancer Res. 59:1999;1061.
58. Crocker P.R., Freeman S., Gordon S., Kelm S. Sialoadhesin binds preferentially to cells of the granulocytic lineage. J Clin Invest. 95:1995;635.
59. Sasaki T., Kojima S. 67Ga uptake and heparan sulfate content of Ehrlich solid tumor in mice. Eur J Nucl Med. 12:1986;182.
60. Roberts R., Gallagher J., Spooncer E., Allen T.D., Bloomfield F., Dexter T.M. Heparan sulphate bound growth factors. a mechanism for stromal cells mediated haemopoiesis Nature. 332:1988;376.
61. Gabrilovich D., Ishida T., Oyama T., Ran S., Kravtsov V., Nadaf S., Carbone D.P. Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood. 92:1998;4150.