ACE I/D Polymorphism and Cardiac Adaptations in Adolescent Athletes

Medicine and Science in Sports and Exercise

Volumn 35, Issue 12, 2003, Pages 1986-1990

  Rizzo, Marta ^a   Gensini, Francesca ^a   Fatini, Cinzia ^a   Manetti, Paolo ^a   Pucci, Nicola ^a   Capalbo, Andrea ^a   Vono, Maria Concetta Robertina ^a   Galanti, Giorgio ^a,b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b NONE   (Italy)

Author keywords

ACE I D polymorphism; Echocardiography; Left ventricular hypertrophy; Left ventricular mass

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADAPTATION; ADOLESCENT; ADULT; ARTICLE; ATHLETE; BIOENERGY; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA POLYMORPHISM; ECHOCARDIOGRAPHY; HEART FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; POLYMERASE CHAIN REACTION; SPORT;

ADOLESCENT; CHILD; CROSS-SECTIONAL STUDIES; ECHOCARDIOGRAPHY; ELECTRIC IMPEDANCE; HUMANS; HYPERTROPHY, LEFT VENTRICULAR; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTORS, ANGIOTENSIN; SPORTS;

EID: 0345529109     PISSN: 01959131     EISSN: None     Source Type: Journal    
DOI: 10.1249/01.MSS.0000098993.51693.0B     Document Type: Article

References (22)

1. BENJAMIN, E. J. Determination of Doppler indexes of left ventricular diastolic function in normal subjects (the Framingham heart study). Am. J. Cardiol. 70:508-515. 1992.
2. DANSER, A. H., M. A. SCHALEKAMP, W. A. BAX et al. Angiotensin-converting enzyme gene in the human heart: effect of deletion/insertion polymorphism. Circulation 92:1387-1388, 1995.
3. DEVEREUX, R. B. Echocardiographic assessment of left ventricular hypertrophy: comparison to necroscopy findings. Am. J. Cardiol. 57:450-458, 1986.
4. DIET. F., C. GRAF, N. MANHNKE, et al. ACE and angiotensinogen gene genotypes and left ventricular mass in athletes. Eur. J. Clin. Invest. 31:836-842, 2001.
5. DOUGLAS, P. S., M. L. O'TOOLE, S. E. KATZ, et al. Left ventricular hypertrophy in athletes. Am. J. Cardiol. 80:1384-1388, 1997.
6. DUBIOS, D., and E. F. DUBIOS. A formula to estimate the approximate surface area if height and weight be known. Arch. Intern. Med. 17:863-877, 1986.
7. FARGARD, R. H. Impact of different sports and training on cardiac structure and function. Cardiol. Clin. 15:397-412, 1997.
8. FATINI, C., R. GUAZZELLI, P. MANETTI, et al. RAS genes influence exercise-induced left ventricular hypertrophy: an elite athletes study. Med. Sci. Sports Exerc. 32:1868-1872. 2000.
9. IGLESIAS, CUBERO, G., A. BATALLA, J. J. RODRIGUEZ REGUERO, et al. Left ventricular mass index and sports: the influence of different sports activities and arterial blood pressure. Int. J. Cardiol. 15:261-265, 2000.
10. KHAN, A. S. D. C. SANE, T. WENNENBURG, and W. E. SONNTAG. Growth hormone, insulin-like growth factor-1 a, insulin-like growth factor-1 and the aging cardiovascular system. Cardiovasc. Res. 54:25-35, 2002.
11. MARSHALL, W. A., and J. M. TANNER. Variation in the pattern of pubertal change in boys. Arch. Dis. Child. 45:13-23, 1970.
12. MONTGOMERY, H. E., P. CLARKSON, C. M. DOLLERY, et al. Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation 96:741-747, 1997.
13. NAGASHIMA, J., H. MUSCHI, H TAKADA, et al. Influence of angiotensin-converting enzyme gene polymorphism on development of athletes heart. Clin. Cardiol. 23:621-624, 2000.
14. NERI SERNERI, G. G., M. BODDI, P. A. MODESTI, et al. Increased cardiac sympathetic activity and insulin-like growth factor-1 formation are associated with physiological hypertrophy in athletes. Circ. Res. 23:1-8. 2001.
15. NIH CONSENSUS STATEMENT. Bioelectrical impedence analysis in body composition measurement: National Institute of Health Technology Assessment Conference Statement. December 12-14, 1994. Nutrition 12:749-762, 1996.
16. PAVLICK, G., Z. OLEXO, A. BANHEGVY, Z. SIDO, and R. FRENKL. Gender differences in the echocardiographic characteristics of the athlete's heart. Acta Physiol. Hung. 86:273-278. 1999.
17. REICHEK, N., J. WILSON, M. J. SUTTON, T. A. PLAPPERT, S. GOLDBERG, and J. W. HIRSHFELD. Noninvasive determination of left ventricular end-systolic tress: validation of the method and initial application. Circulation 65:99-108, 1982.
18. RIGAT, B., C. HUBERT, P. CORVOL, and F. SOUBRIER. PCR detection of the insertion/deletion polymorphism of the human angiotensin-converting enzyme gene (DCP1)(dipeptidyl carboxypeptidase 1). Nucl. Acids. Res. 20:1433, 1992.
19. SAHN, D. J., A. DE MARIA, J. KISSLO, and A. WEYMAN. The Committee on M-mode standardization of the American Society of Echocardiography: recommendation regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 58:1072-1083, 1978.
20. SOMAUROO, J. D., J. PYATT, M. JACKSON, R. A. PERRY, and D. R. RAMSDALE. An echocardiographic assessment of cardiac morphology and common ECG findings in teenage professional soccer players: reference ranger for use in screening Heart 85:649-654, 2001.
21. SPIRITO, P., A. PELLICCIA, A. PROSHAN, et al. Morphology of the "athlete's heart" assessed by Echocardiographic in 947 elite athletes representing 27 sports. Am. J. Cardiol. 74:802-806, 1994.
22. TEICHOLZ, L. E., T. KREULEN, M. V. HERMAN, and R. GORLIN. Problems in echocardiographic volume determinations in the presence or absence of asynergy. Am. J. Cardiol. 37:7, 1976.