Intramyocardial blood volume, perfusion and transit time in response to embolization of different sized microvessels

Cardiovascular Research

Volumn 57, Issue 3, 2003, Pages 843-852

  Möhlenkamp, Stefan ^a,b   Beighley, Patricia E ^a   Pfeifer, Eric A ^a   Behrenbeck, Thomas R ^a   Sheedy II, Patrick F ^a   Ritman, Erik L ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Blood flow; Coronary circulation; Microcirculation

Indexed keywords

ADENOSINE; MICROSPHERE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DIAMETER; ARTERY EMBOLISM; ARTICLE; BLOOD VESSEL INJURY; BLOOD VOLUME; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DILATATION; CORONARY ARTERY OBSTRUCTION; HEART MUSCLE INJURY; HEART MUSCLE PERFUSION; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE; ANIMALS; BLOOD VOLUME; CORONARY CIRCULATION; CORONARY DISEASE; EMBOLISM; HEMODYNAMIC PROCESSES; MALE; MICROCIRCULATION; MICROSPHERES; MYOCARDIUM; SWINE; VASODILATOR AGENTS;

EID: 0345505247     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00736-8     Document Type: Article

References (26)

1. Topol E.J., Yadav J.S. Recognition of the importance of embolization in atherosclerotic vascular disease. Circulation. 101:2000;570-580.
2. Erbel R., Heusch G. Coronory microembolization. J Am Coll Cardiol. 36:2000;22-24.
3. Heusch G., Schulz R., Baumgart D., Haude M., Erbel R. Coronary microembolization. Prog Cardiovasc Dis. 44:2001;217-230.
4. Falk E. Unstable angina with fatal outcome: dynamic coronary thrombosis leading to infarction and/or sudden death. Autopsy evidence of recurrent mural thrombosis with peripheral embolization culminating in total vascular occlusion. Circulation. 71:1985;699-708.
5. Willerson J.T., Cohen L.S., Maseri A. Pathophysiology and clinical recognition. Willerson J.T., Cohn J.N. Cardiovascular medicine. 1995;333-365 Churchill Livingston, New York.
6. Van Liebergen R.A.M., Piek J.J., Koch K.T., de Winter R.J., Li K.I. Immediate and long-term effect of balloon angioplasty or stent implantation on the absolute and relative coronary blood flow velocity reserve. Circulation. 98:1998;2133-2140.
7. Kern M.J., Puri S., Bach R.G., et al. Abnormal coronary flow velocity reserve after coronary artery stenting in patients. Role of relative coronary reserve to assess potential mechanisms. Circulation. 100:1999;2491-2498.
8. Arras M., Strasser R., Mohri M., et al. Tumor necrosis factor α is expressed by monocytes/macrophages following cardiac microembolization and is antagonized by cyclosporine. Basic Res Cardiol. 93:1998;97-107.
9. Hori M., Inoue M., Kitakaze M., et al. Role of adenosine in hyperemic response of coronary blood flow in microcirculation. Am J Physiol. 250:1986;H509-H518.
10. Grund F., Sommerschild H.T., Lyberg T., Kirkeboen K.A., Ilebekk A. Microembolization in pigs: effects on coronary blood flow and myocardial ischemic tolerance. Am J Physiol. 277:1999;H533-H542.
11. Dörge H., Neumann T., Behrends M., et al. Perfusion-contraction mismatch with coronary microvascular obstruction: role of inflammation. Am J Physiol. 279:2000;H2587-2592.
12. Herrmann J., Haude M., Lerman A., et al. Abnormal coronary flow velocity reserve after coronary intervention is associated with cardiac marker elevation. Circulation. 103:2001;2339-2345.
13. Möhlenkamp S., Lerman L.O., Lerman A., et al. Minimally invasive evaluation of coronary microvascular function by electron beam computed tomography. Circulation. 102:2000;2411-2416.
14. Möhlenkamp S., Behrenbeck T.R., Lerman A., et al. Long-term changes in intramyocardial microvascular function using EBT - preliminary results from a porcine model. Radiology. 221:2001;229-236.
15. Lerman L.O., Siripornpitak S., Maffei N.L., Sheedy P.F. II, Ritman E.L. Measurement of in vivo myocardial microcirculatory function with electron beam CT. J Comp Assist Tomogr. 23:1999;390-398.
16. Lund P.E., Naessens L.C., Seaman C.A., Reyes D.A., Ritman E.L. Volume of myocardium perfused by coronary artery branches as estimated from 3D micro-CT images of rat hearts. Proc SPIE Med Imaging. 3978:2000;314-319.
17. Liu Y.H., Bahn R.C., Ritman E.L. Microvascular blood volume to flow relationship in porcine heart wall: Whole body CT evaluation in vivo. Am J Physiol. 269:1995;H1820-H1826.
18. Herzberg R.M., Rubio R., Berne R.M. Coronary occlusion and embolization: effect on blood flow in adjacent arteries. Am J Physiol. 210:1966;169-175.
19. West J.W., Kobayashi T., Anderson F.S. Effects of selective coronary embolization on coronary blood flow and coronary sinus venous blood oxygen saturation in dogs. Circ Res. 10:1962;722-738.
20. Hori M., Tamai J., Kitakaze M., et al. Adenosine-induced hyperemia attenuates myocardial ischemia in coronary microembolization in dogs. Am J Physiol. 257:1989;H244-H251.
21. Van der Ploeg C.P.B., Dankelman J., Spaan J.A.E. Classical Krogh model does not apply well to coronary oxygen exchange. Adv Exp Med Biol. 345:1994;299-304.
22. Grover G.J., Rosolowski M., Kedem J.K., Weiss H.R. Effect of hypoxia and adenosine on the microvascular reserve in the rabbit heart. Microcirc Endothel Lymph. 3:1986;359-382.
23. Weiss H.R., Conway R.S. Morphometric study of the total perfusion arteriolar and capillary network of the rabbit left ventricle. Cardiovasc Res. 19:1985;343-354.
24. Skyschally A., Schulz R., Erbel R., Heusch G. Reduced coronary and inotropic reserves with coronary microembolization. Am J Physiol. 282:2002;H611-H614.
25. Schulz R., Rose J., Post H., Heusch G. Involvement of endogenous adenosine in ischemic preconditioning in swine. Pflügers Arch. 430:1995;273-282.
26. Spaan J.A.E. Structure of the coronary arterial tree. Spaan J.A.E. Coronary blood flow. 1991;40-48 Kluwer, Dordrecht.