Tumor necrosis factor-alpha is expressed by monocytes/macrophages following cardiac microembolization and is antagonized by cyclosporine

Basic Research in Cardiology

Volumn 93, Issue 2, 1998, Pages 97-107

  Arras, M ^a   Strasser, R ^a   Mohri, M ^a   Doll, R ^a   Eckert, P ^a   Schaper, W ^a   Schaper, J ^a  

^a MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

Angiogenesis; Cyclosporine; Dexamethasone; Ischemia; TNF

Indexed keywords

ANTIBODY; CYCLOSPORIN; CYCLOSPORIN A; DEXAMETHASONE; ENZYME ANTIBODY; LYSOZYME; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HEART LEFT VENTRICLE; HEART MUSCLE ISCHEMIA; IMMUNOFLUORESCENCE; INFLAMMATION; INTRAMUSCULAR DRUG ADMINISTRATION; MACROPHAGE; MALE; MICROEMBOLISM; MONOCYTE; NONHUMAN; ORAL DRUG ADMINISTRATION; PROTEIN EXPRESSION; SCAR; SWINE; TISSUE NECROSIS; WOUND HEALING;

ANIMALS; CORONARY VESSELS; CYCLOSPORINE; DEXAMETHASONE; EMBOLISM; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; MACROPHAGES; MALE; MICROCIRCULATION; MONOCYTES; MYOCARDIAL ISCHEMIA; NECROSIS; SWINE; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031899148     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003950050069     Document Type: Article

References (60)

1. Arras M, Höche A, Bohle R, Eckert W, Riedel W, Schaper J (1996) Tumor necrosis factor-alpha in macrophages of heart, liver, kidney, and in the pituitary gland. Cell Tissue Res 285: 39-49
2. Arras M, Mohri M, Pich S, Lindert-Heimberg S, Schaper J (1993) Tumor necrosis factor-alpha (TNF-alpha) is produced in monocytes / macrophages in ischemic porcine myocardium. J Mol Cell Cardiol 25 (Suppl I): IX P 8 (abstr)
3. Arras M, Mohri M, Sack S, Schwarz ER, Schaper J, Schaper W (1992) Macrophages accumulate and release tumor necrosis factor-alpha in the ischemic porcine myocardium. Circulation 86 (Suppl I): 0129 (abstr)
4. Beutler B, Milsark IW, Cerami AC (1985) Passive immunization against cachectin/ tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229: 869-871
5. Beutler BA, Milsark IW, Cerami A (1985) Cachetin/tumor necrosis factor: Production, distribution, and metabolic fate in vivo. J Immunol 135: 3972-3977
6. Boussiotis V, Nadler LM, Strominger JL, Goldfeld E (1994) Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells. Proc Natl Acad Sci 91: 7007-7011
7. Chensue SW, Terebuh PD, Remick DG, Scales WE, Kunkel SL (1991) In vivo biologic and immunohistochemical analysis of interleukin-1 alpha, beta and tumor necrosis factor during experimental endotoxemia. Am J Pathol 138: 395-402
8. Chilian WM, Mass HJ, Williams SE, Layne SM, Smith ES, Scheel KW (1990) Microvascular occlusions promote coronary collateral growth. Am J Physiol 258: H1103-H1111
9. Fahey TJ, Sherry B, Tracey KJ, van Deventer S, Jones WG, Minei JP, Morgello S, Shires GT, Cerami A (1990) Cytokine production in a model of wound healing: the appearance of MIP-1, MIP-2, cachectin/ TNF and IL-1. Cytokine 2: 92-99
10. Falk E, Fallon JT, Mailhac A, Fernandez-Ortiz A, Meyer BJ, Weng D, Shah PK, Badimon JJ, Fuster V (1994) Muramidase: a useful monocyte/macrophage immunocytochemical marker in swine, of special interest in experimental cardiovascular disease. Cardiovasc Pathol 3: 183-189
11. Field G, Conn CC, McClanahan TB, Nao BS, Kluger MJ, Gallagher KP (1994) Tumor necrosis factor and interleukin-6 are not elevated in venous blood from ischemic canine myocardium. PSEBM 206: 384-391
12. Folkman J (1985) Regulation of angiogenesis: a new function of heparin. Biochem Pharmacol 34: 905-909
13. Frater-Schröder M, Risau W, Hallmann R, Gautschi P, Böhlen P (1987) Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo. Proc Natl Acad Sci USA 84: 5277-5281
14. Frering B, Philip I, Dehoux M, Rolland C, Langlois JM, Desmonts JM (1994) Circulating cytokines in patients undergoing normothermic cardiopulmonary bypass. J Thorac Cardiovasc Surg 108: 636-41
15. Goldfeld AE, Flemington EK, Boussiotis VB, Theodos CM, Titus RG, Strominger JL, Speck S (1992) Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobuline and blocked by cyclosporin A and FK506 in human B cells. Proc Natl Acad Sci 89: 12198-12201
16. Hanazawa S, Takeshita A, Amano S, Semba T, Nirazuka T, Katoh H, Kitano S (1993) Tumor necrosis factor-alpha induced expression of monocyte chemoattractant JE vis fos and jun genes in clonal osteoblastic MC3T3-E1 cells. J Biol Chem 268: 9526-32
17. Hennein HA, Ebba H, Rodriguez JL, Merrick SH, Keith FM, Bronstein MH, Leung JM, Mangano DT, Greenfield LJ, Rankin JS (1994) Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revascularization. J Thorac Cardiovasc Surg 108: 626-35
18. Herskowitz A, Choi S, Ansari AA, Wesselingh S (1995) Cytokine mRNA expression in postischemic/reperfused myocardium. Am J Path 146: 419-428
19. Hidalgo HA, Helmke RJ, German VF, Mangos JA (1992) The effects of cyclosporine and dexamethasone on an alveolar macrophage cell line. Transplantation 53: 620-3
20. Hsi ED, Remick DG (1993) Methods in laboratory investigation. Rapid determination of cell-associated tumor necrosis factor production by flow cytometry. Lab Invest 68: 740-745
21. Hummel M, Czerlinski S, Friedel N, Liebenthal C, Hasper D, von Baehr R, Hetzer R, Volk HD (1994) Interleukin-6 and interleukin-8 concentrations as predictors of outcome in ventricular assist device patients before heart transplantation. Crit Care Med 22: 448-454
22. Jennings RB, Reimer KA (1981) Lethal myocardial ischemic injury. Am J Pathol 102: 241-245
23. Jennings RB, Sommers HM, Smyth GA, Flack HA, Linu H (1960) Myocardial necrosis induced by temporary occlusion of a coronary artery in the dog. Arch Pathol 70: 68-78
24. Jesmok G, Lindsey C, Duerr M, Fournel M, Emerson T (1992) Efficacy of monoclonal antibody against human recombinant tumor necrosis factor in E. coli-challenged swine. Am J Pathol 141: 1197-1207
25. Katz SD, Rao R, Berman JW, Schwarz M, Demopoulos L, Bijou R, LeJemtel TH (1994) Pathophysiological correlates of increased serum tumor necrosis factor in patients with congestive heart failure relation to nitric oxide-dependent vasodilation in the forearm circulation. Circulation 90: 12-16
26. Knolle P, Lohr H, Treichel U, Dienes HP, Lohse A, Schlaack J, Gerken G (1995) Parenchymal and nonparenchymal liver cells and their interaction in the local immune response. Zeitschrift für Gastroenterologie 33:613-620
27. Kunkel EJ, Jung U, Bullard DC, Norman KE, Wolitzky BA, Vestweber D, Beaudet AL, Ley K (1996) Absence of traumainduced leukocyte rolling in mice deficient in both P-selectin and intercellular adhesion molecule I. J Exp Med 183: 57-65
28. Latini R, Correale E, Dinarello A, Fantuzzi G, Fresco C, Maggioni AP, Mengozzi M, Raman S, Shapiro L, Sironi M, Tognoni G, Turato R, Ghezzi P (1994) Cytokines in acute myocardial infarction. Selective increase in circulating tumor necrosis factor, its soluble receptor, and interleukin-1 receptor antagonist. J Cardiovasc Pharmacol 23: 1-6
29. Ledda-Columbano GM, Columbano A, Cannas A, Simbula G, Okita K, Kayano K, Kubo Y, Katyal SL, Shinozuka H (1994) Dexamethasone inhibits induction of liver tumor necrosis factor-alpha mRNA and liver growth induced by lead nitrate and ethylene dibromide. Am J Pathol 145: 951-958
30. Leibovich SJ, Polverini PJ, Shepard HM, Wiseman DM, Shively V, Nuseir N (1987) Macrophage-induced angiogenesis is mediated by tumor necrosis factor-alpha. Nature 329: 630-632
31. Levine B, Kalmman J, Mayer L, Fillit HM, Packer M (1990) Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med 323: 236-241
32. Mathison JC, Wolfson E, Ulevitch RJ (1988) Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits. J Clin Invest 81: 1925-1937
33. McLoughlin PJ, Davies HM, Aikawa A (1990) TNF in normal plasma. Lancet 336: 1014-1015
34. Mohri M, Schaper W (1993) Angiogenesis in porcine hearts with coronary microembolization. In: Schaper W, Schaper J (eds) Collateral Circulation - Heart, Brain, Kidney, Limbs. Kluwer Academic Publishers, Boston, Dordrecht, London, pp 103-121
35. Mooney DP, O'Reilly M, Gamelli RL (1990) Tumor necrosis factor and wound healing. Ann Surg 211: 124-129
36. Nguyen DT, Eskandai MK, DeForge LE, Raiford CL, Strieter RM, Kunkel SL, Remick DG (1990) Cyclosporin a modulation of tumor necrosis factor gene expression and effects in vitro and in vivo. J Immunol 144: 3822-8
37. Oremek G (1992) Enzymimmunoassaystabilität von Tumor Nekrosis-Faktor-alpha in Plasma und Serum. Med Klinik 87: 626-630
38. Paine R, Rolfe MW, Standiford TJ, Burdick MD, Rollins BJ, Strieter RM (1993) MCP-1 expression by rat Type II alveolar epithel cells in primary culture. J Immunology 150: 4561-70
39. Pandey A, Shao H, Marks RM, Polverini PJ, Dixit VM (1995) Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis. Science 268: 567-9
40. Peri G, Milanese C, Matteucci C, Ruco L, Zhou D, Sozzani S, Coletta I, Mantovani A (1994) A new monoclonal antibody (5D3-F7) which recognizes human monocytechemotactic protein-1 but not related chemokines. Development of a sandwich ELISA and in situ detection of producing cells. J Immunol Methods 174: 249-57
41. Rabinovici R, Feuerstein G, Abdullah F, Whiteford M, Borboroglu P, Sheikh E, Phillip DR, Ovadia P, Bobroski L, Bagasra O, Neville LF (1996) Locally produced tumor necrosis factor-alpha mediates interleukin-2-induced injury. Circ Res 78: 329-36
42. Remick DG, Nguyen DT, Eskandari MK, Strieter RM, Kunkel SL (1989) Cyclosporine a inhibits TNF production without decreasing TNF mRNA levels. Biochem Biophys Res Comm 161: 551-5
43. Remick DG, Strieter RM, Eskandari MK, Nguyen DT, Genord MA, Raiford CL, Kunkel SL (1990) Role of tumor necrosis factor-α in lipopolysaccharide-induced pathologic alterations. Am J Pathol 136: 49-60
44. Remick DG, Strieter RM, Lynch III JP, Nguyen D, Eskandari M, Kunkel SL (1989) In vivo dynamics of murine tumor necrosis factor-α gene expression. Lab Invest 60: 766-771
45. Rosenbaum JT, Howes EL, Rubin RM, Samples JR (1988) Ocular inflammatory effects of intravitreally-injected tumor necrosis factor. Am J Pathol 133: 47-53
46. Saklatvala J (1995) Intracellular signalling mechanisms interleukin 1 and tumor necrosis factor: possible targets for therapy. British Medical Bulletin 51: 402-18
47. Sawa Y, Nagasawa K, Amemlya A, Shirakura R (1992) Evidence for hypoxic myocyte derived TNF-alpha which may promote neutrophil transendothelial migration. Circulation 86 (Suppl I): 1170 (abstr)
48. Schaper J, Mulch J, Winkler B, Schaper W (1979) Ultrastructural, functional, and biochemical criteria for estimation of reversibility of ischemic injury: A study on the effects of global ischemia on the isolated dog heart. J Mol Cell Cardiol 11: 521-541
49. Schaper J, Weihrauch D (1993) Collateral vessel development in the porcine and canine heart. In: Schaper W, Schaper J (eds) Collateral Circulation - Heart, Brain, Kidney, Limbs. Kluwer Academic Publishers, Boston, Dordrecht, London, pp 65-102
50. Smith CS, Ortega G, Parker L, Shearer WT (1994) Cyclosporin a blocks induction of tumor necrosis factor-alpha in human B lymphocytes. Biochemical and Biophysical Research Communications 20: 383-390
51. Stellato C, Beck LA, Gorgone GA, Proud D, Schall TJ, Ono SJ, Schleimer RP (1995) Expression of the chemokine RANTES by a human bronchial epithelial cell line. Modulation by cytokines and gluccocorticoids. J Immunol 155: 410-8
52. Stricter RM, Kunkel SL (1994) Acute lung injury: the role of cytokines in the elicitation of neutrophils. J Invest Med 42: 640-51
53. Svensson U, Holst E, Sundler R (1995) Cyclosporin-sensitive expression of cytokine mRNA in mouse macrophages responding to bacteria. Mol Immunol 32: 157-165
54. Tokunaga A, Onda M, Fujita I, Okuda T, Mizutani T, Kiyama T, Matsukura N, Hunt TK (1993) Sequential changes in the cell mediators of peritoneal and wound fluids after surgery. Jpn Surg 23: 841-844
55. Torre-Amione G, Kapadia S, Lee J, Durand JB, Bies RD, Young JB, Mann DL (1996) Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart. Circulation 93: 704-711
56. Ulich TR, Guo K, del Castillo J (1989) Endotoxin-induced cytokine gene expression in vivo. I. Expression of tumor necrosis factor mRNA in visceral organs under physiologic conditions and during endotoxemia. Am J Pathol 134: 11-14
57. Weihrauch D, Arras M, Zimmermann R, Münkel B, Schaper J (1993) Monocytes/ macrophages and fibroblasts play an important role in angiogenesis and repair in ischemic porcine myocardium Circulation 88 (Suppl): 2382 (abstr)
58. Weihrauch D, Arras M, Zimmermann R, Schaper J (1995) Importance of monocytes/macrophages and fibroblasts for healing of micronecroses in porcine myocardium. Mol Cell Bioch 147: 13-19
59. Wiedermann CJ, Beimpold H, Herold M, Knapp E, Braunsteiner H (1993) Increased levels of serum neopterin and decreased production of neutrophil superoxide anions in chronic heart failure with elevated levels of tumor necrosis factor-alpha. J Am Coll Cardiol 22: 1897-901
60. Zimmermann R, Münkel B, Mohri M, Kluge A, Schaper J, Schaper W (1993) Histone H3 - a marker for mitosis in ischemic porcine myocardium. J Mol Cell Cardiol 25 (Suppl I): IX P 4 (abstr)