Correlated Discharge among Cell Pairs within the Oculomotor Horizontal Velocity-to-Position Integrator

Journal of Neuroscience

Volumn 23, Issue 34, 2003, Pages 10852-10858

  Aksay, Emre ^a   Baker, Robert ^b   Seung, H Sebastian ^c   Tank, David W ^a  

^a PRINCETON UNIVERSITY   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Eye position; Fixation; Integrator; Memory; Persistence; Synchrony

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BRAIN NERVE CELL; BRAIN STEM; CONTROLLED STUDY; CORRELATION ANALYSIS; EXCITATION; EYE MOVEMENT CONTROL; EYE POSITION; GOLDFISH; NONHUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; SYNAPTIC TRANSMISSION; VISION;

EID: 0345491877     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-34-10852.2003     Document Type: Article

References (38)

1. Aksay E, Baker R, Seung HS, Tank DW (2000) Anatomy and discharge properties of pre-motor neurons in the goldfish medulla that have eye-position signals during fixations. J Neurophysiol 84:1035-1049.
2. Aksay E, Gamkrelidze G, Seung HS, Baker R, Tank DW (2001) In vivo intracellular recording and perturbation of persistent activity in a neural integrator. Nat Neurosci 4:184-193.
3. Cannon SC, Robinson DA (1987) Loss of the neural integrator of the oculomotor system from brain stem lesions in monkey. J Neurophysiol 57:1383-1409.
4. Cannon SC, Robinson DA, Shamma S (1983) A proposed neural network for the integrator of the oculomotor system. Biol Cybern 49:127-136.
5. Cheron G, Godaux E, Laune JM, Vanderkelen B (1986) Lesions in the cat prepositus complex: effects on the vestibulo-ocular reflex and saccades. J Physiol (Lond) 372:75-94.
6. Delgado-Garcia JM, Vidal PP, Gomez C, Berthoz A (1989) A neurophysiological study of prepositus hypoglossi neurons projecting to oculomotor and preoculomotor nuclei in the alert cat. Neuroscience 29:291-307.
7. Egorov AV, Hamam BN, Fransen E, Hasselmo ME, Alonso AA (2002) Graded persistent activity in entorhinal cortex neurons. Nature 420:133-134.
8. Engel AK, Singer W (2001) Temporal binding and the neural correlates of sensory awareness. Trends Cogn Sci 5:16-25.
9. Escudero M, de la Cruz RR, Delgado-Garcia JM (1992) A physiological study of vestibular and prepositus hypoglossi neurones projecting to the abducens nucleus in the alert cat. J Physiol (Lond) 458:539-560.
10. Fukushima K, Kaneko CRS, Fuchs AF (1992) The neuronal substrate of integration in the oculomotor system. Prog Neurobiol 39:609-639.
11. Galiana HL, Outerbridge JS (1984) A bilateral model for central neural pathways in vestibuloocular reflex. J Neurophysiol 51:210-241.
12. Goldman MS, Kaneko CR, Major G, Aksay E, Tank DW, Seung HS (2002) Linear regression of eye velocity on eye position and head velocity suggests a common oculomotor neural integrator. J Neurophysiol 88:659-665.
13. Goldman MS, Levine JH, Major G, Tank DW, Seung HS (2003) Dendritic hysteresis adds robustness to persistent neural activity in a model neural integrator. Cereb Cortex 13:1185-1195.
14. Institute of Laboratory Animal Resources (1996) Guide for the care and use of laboratory animals. Washington, DC: National Academy.
15. Kamath BY, Keller EL (1976) A neurological integrator for the oculomotor control system. Math Biosci 30:341-352.
16. Kaneko CRS (1997) Eye movement deficits after ibotenic acid lesions of the nucleus prepositus hypoglossi in monkeys. I. Saccades and Fixation. J Neurophysiol 78:1753-1768.
17. Koulakov AA, Raghavachari S, Kepecs A, Lisman JE (2002) Model for a robust neural integrator. Nat Neurosci 5:775-782.
18. Loewenstein Y, Sompolinsky H (2003) Temporal integration by calcium dynamics in a model neuron. Nat Neurosci 6:961-967.
19. Lopez-Barneo J, Darlot C, Berthoz A, Baker R (1982) Neuronal activity in prepositus nucleus correlated with eye movement in the alert cat. J Neurophysiol 47:329-352.
20. Lorente de No R (1933) Vestibulo-ocular reflex arc. Arch Neurol Psychiatry 30:245-291.
21. Lu T, Trussell LO (2000) Inhibitory transmission mediated by asynchronous transmitter release. Neuron 26:683-694.
22. Luschei ES, Fuchs AF (1972) Activity of brain stem neurons during eye movements of alert monkeys. J Neurophysiol 35:444-461.
23. McCrea RA, Baker R (1985a) Cytology and intrinsic organization of the perihypoglossal nuclei in the cat. J Comp Neurol 237:360-376.
24. McCrea RA, Baker R (1985b) Anatomical connections of the nucleus prepositus of the cat. J Comp Neurol 237:377-407.
25. McCrea RA, Yoshida K, Berthoz A, Baker R (1980) Eye movement related activity and morphology of second order vestibular neurons terminating in the cat abducens nucleus. Exp Brain Res 40:468-473.
26. McCrea RA, Strassman A, May E, Highstein SM (1987) Anatomical and physiological characteristics of vestibular neurons mediating the horizontal vestibulo-ocular reflex of the squirrel monkey. J Comp Neurol 264:547-570.
27. McFarland JL, Fuchs AF (1992) Discharge patterns in nucleus prepositus hypoglossi and adjacent medial vestibular nucleus during horizontal eye movement in behaving macaques. J Neurophysiol 68:319-332.
28. Moschovakis AK (1997) The neural integrators of the mammalian saccadic system. Front Biosci 2:552-577.
29. Pastor AM, de la Cruz RR, Baker R (1994) Eye position and eye velocity integrators reside in separate brainstem nuclei. Proc Natl Acad Sci USA 91:807-811.
30. Perkel D, Gerstein G, Moore G (1967) Neuronal spike trains and stochastic point processes. II. Simultaneous spike trains. Biophys J 7:419-440.
31. Perkel D, Gerstein G, Smith M, Tatton W (1975) Nerve-impulse patterns: a quantitative display technique for three neurons. Brain Res 100:271-296.
32. Pesaran B, Pezaris JS, Sahani M, Mitra PP, Andersen RA (2002) Temporal structure in neuronal activity during working memory in macaque parietal cortex. Nat Neurosci 5:805-811.
33. Robinson DA (1974) The effect of cerebellectomy on the cat's vestibuloocular integrator. Brain Res 71:195-207.
34. Seung HS (1996) How the brain keeps the eyes still. Proc Natl Acad Sci USA 93:13339-13344.
35. Seung HS, Lee DD, Reis BY, Tank DW (2000) Stability of the memory of eye position in a recurrent network of conductance-based model neurons. Neuron 26:259-271.
36. Shen L (1989) Neural integration by short term potentiation. Biol Cybern 61:319-325.
37. Tegner J, Compte A, Wang XJ (2002) The dynamical stability of reverberatory neural circuits. Biol Cybern 87:471-481.
38. Zee DS, Yamazaki A, Butler PH, Gucer G (1981) Effects of ablation of flocculus and paraflocculus of eye movements in primate. J Neurophysiol 46:878-899.