Robust Persistent Neural Activity in a Model Integrator with Multiple Hysteretic Dendrites per Neuron

Cerebral Cortex

Volumn 13, Issue 11, 2003, Pages 1185-1195

  Goldman, Mark S ^a,d   Levine, Joseph H ^b   Major, Guy ^c   Tank, David W ^c   Seung, H S ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b USA   (United States)

^c PRINCETON UNIVERSITY   (United States)

^d WELLESLEY COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; DENDRITIC CELL; HYSTERESIS; NERVE CONDUCTION; NERVE EXCITABILITY; NONHUMAN; OCULOMOTOR SYSTEM; PRIORITY JOURNAL; SACCADIC EYE MOVEMENT; SHORT TERM MEMORY; STIMULUS RESPONSE; VESTIBULOOCULAR REFLEX; WORKING MEMORY;

ACTION POTENTIALS; DENDRITES; EYE MOVEMENTS; NEURAL NETWORKS (COMPUTER); NEURONS;

EID: 0142250862     PISSN: 10473211     EISSN: None     Source Type: Journal    
DOI: 10.1093/cercor/bhg095     Document Type: Article

References (27)

1. Aksay E, Baker R, Seung HS, Tank DW (2000) Anatomy and discharge properties of pre-motor neurons in the goldfish medulla that have eye-position signals during fixations. J Neurophysiol 84:1035-1049.
2. Aksay E, Gamkrelidze G, Seung HS, Baker R, Tank DW (2001) In vivo intracellular recording and perturbation of persistent activity in a neural integrator. Nat Neurosci 4:184-193.
3. Aksay E, Major G, Goldman MS, Baker R, Seung HS, Tank DW (2003) History dependence of rate covariation between neurons during persistent activity in an oculomotor integrator. Cereb Cortex 13:1173-1184.
4. Camperi M, Wang XJ (1998) A model of visuospatial working memory in prefrontal cortex: recurrent network and cellular bistability. J Comput Neurosci 5:383-405.
5. Cannon SC, Robinson DA (1985) An improved neural-network model for the neural integrator of the oculomotor system: more realistic neuron behavior. Biol Cybern 53:93-108.
6. Cannon SC, Robinson DA, Shamma S (1983) A proposed neural network for the integrator of the oculomotor system. Biol Cybern 49:127-136.
7. Goldman MS, Kaneko CR, Major G, Aksay E, Tank DW, Seung HS (2002a) Linear regression of eye velocity on eye position and head velocity suggests a common oculomotor neural integrator. J Neurophysiol 88:659-665.
8. Goldman MS, Levine JH, Major G, Aksay E, Tank DW, Seung HS (2002b) Dendritic bistability increases the robustness of persistent neural activity in a model oculomotor neural integrator. Soc Neurosci Abstr 28:266.14.
9. Hounsgaard J, Kiehu O (1993) Calcium spikes and calcium plateaux evoked by differential polarization in dendrites of turtle motoneurones in vitro. J Physiol (Lond) 468:245-259.
10. Kamath BY, Keller EL (1976) A neurological integrator for the oculomotor control system. Math Biosci 30:341-352.
11. Koch C, Poggio T, Torre V (1982) Retinal ganglion cells: a functional interpretation of dendritic morphology. Philos Trans R Soc Lond B Biol Sci 298:227-263.
12. Koulakov AA, Raghavachari S, Kepecs A, Lisman JE (2002) Model for a robust neural integrator. Nat Neurosci 5:775-782.
13. Lee RH, Heckman CJ (1998a) Bistability in spinal motoneurons in vivo: systematic variations in persistent inward currents. J Neurophysiol 80:583-593.
14. Lee RH, Heckman CJ (1998b) Bistability in spinal motoneurons in vivo: systematic variations in rhythmic firing patterns. J Neurophysiol 80:572-582.
15. Lisman JE, Fellous JM, Wang XJ (1998) A role for NMDA-receptor channels in working memory. Nat Neurosci 1:273-275.
16. Pastor AM, De la Cruz RR, Baker R (1994) Eye position and eye velocity integrators reside in separate brainstem nuclei. Proc Natl Acad Sci USA 91:807-811.
17. Poirazi P, Brannon T, Mel BW (2003a) Arithmetic of subthreshold synaptic summation in a model CA1 pyramidal cell. Neuron 37:977-987.
18. Poirazi P, Brannon T, Mel BW (2003b) Pyramidal neuron as two-layer neural network. Neuron 37:989-999.
19. Pouget A, Latham P (2002) Digitized neural networks: long-term stability from forgetful neurons. Nat Neurosci 5:709-710.
20. 2+ channels in dendrites. J Neurosci 13:4609-4621.
21. Robinson DA (1981) Control of eye movements. In: Handbook of physiology. The nervous system visual motor control (Desmedt JE, ed.), pp. 1275-1320. Bethesda, MD: American Physiology Society.
22. Rosen MJ (1972) A theoretical neural integrator. IEEE Trans Biomed Eng 19:362-367.
23. Schiller J, Schiller Y (2001) NMDA receptor-mediated dendritic spikes and coincident signal amplification. Curr Opin Neurobiol 11:343-348.
24. Schiller J, Major G, Koester HJ, Schiller Y (2000) NMDA spikes in basal dendrites of cortical pyramidal neurons. Nature 404:285-289.
25. Seung HS (1996) How the brain keeps the eyes still. Proc Natl Acad Sci USA 93:13339-13344.
26. Seung HS, Lee DD, Reis BY, Tank DW (2000) Stability of the memory of eye position in a recurrent network of conductance-based model neurons. Neuron 26:259-271.
27. 2+ accumulations in dendrites of neocortical pyramidal neurons: an apical band and evidence for two functional compartments. Neuron 13:23-43.