Azelastine inhibits secretion of IL-6, TNF-α and IL-8 as well as NF-κB activation and intracellular calcium ion levels in normal human mast cells

International Archives of Allergy and Immunology

Volumn 132, Issue 3, 2003, Pages 231-239

  Kempuraj, Duraisamy ^a   Huang, Man ^a   Kandere Grzybowska, Kristiana ^a   Basu, Subimal ^a   Boucher, William ^a   Letourneau, Richard ^a   Athanassiou, Achilles ^a   Theoharides, Theoharis C ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Azelastine; Cytokines; Interleukin 6; Interleukin 8; Ophthalmic solution; Tumor necrosis factor

Indexed keywords

AZELASTINE; CALCIUM ION; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; MAST CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIME; UMBILICAL CORD BLOOD;

CALCIUM; CELLS, CULTURED; HISTAMINE H1 ANTAGONISTS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; MAST CELLS; NF-KAPPA B; PHTHALAZINES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0345491514     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000074304     Document Type: Article

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