Flow dynamics of QW7437, a new dodecafluoropentane ultrasound contrast agent, in the microcirculation: Microvascular mechanisms for persistent tissue echo enhancement

Journal of the American College of Cardiology

Volumn 34, Issue 2, 1999, Pages 578-586

  Yasu, Takanori ^a   Schmid Schönbein, Geert W ^b   Cotter, Bruno ^a   Demaria, Anthony N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRAST MEDIUM; PERFLUOROPENTANE; QW 7437; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL CELL; ARTICLE; BLOOD FLOW VELOCITY; CONTRAST ENHANCEMENT; ERYTHROCYTE; FLOW KINETICS; FLUORESCENCE ANALYSIS; INTRAVENOUS DRUG ADMINISTRATION; MESENTERY BLOOD FLOW; MICROCIRCULATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD FLOW VELOCITY; CONTRAST MEDIA; ECHOCARDIOGRAPHY; ERYTHROCYTES; FLUORESCENT DYES; FLUOROCARBONS; MESENTERY; MICROCIRCULATION; MICROSCOPY, FLUORESCENCE; RATS; RATS, WISTAR;

EID: 0345440127     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(99)00209-0     Document Type: Article

References (31)

1. Feinstein S.B., Lang R.M., Dick C., et al. Contrast echocardiography during coronary arteriography in humans perfusion and anatomic studies . J Am Coll Cardiol. 11:1988;59-65.
2. Ito H., Tomooka T., Sakai N., et al. Lack of myocardial perfusion immediately after successful thrombolysis a predictor of poor recovery of left ventricular function in anterior myocardial infarction . Circulation. 85:1992;1699-1705.
3. Sabia P.J., Powers E.R., Ragosta M., Sarembock I.J., Burwell L.R., Kaul S. An association between collateral blood flow and myocardial viability in patients with recent myocardial infarction. N Engl J Med. 327:1992;1825-1831.
4. Grayburn P.A., Erickson J.M., Escobar J., Womack L., Velasco C.E. Peripheral intravenous myocardial contrast echocardiography using a 2% dodecafluoropentane emulsion identification of myocardial risk area and infarct size in the canine model of ischemia . J Am Coll Cardiol. 26:1995;1340-1347.
5. Correas J.M., Quay S.D. EchoGen emulsion a new ultrasound contrast agent based on phase shift colloids . Clin Radiol. 51:(Suppl I):1996;11-14.
6. Beppu S., Matsuda H., Shishido T., Matsumura M., Miyatake K. Prolonged myocardial contrast echocardiography via peripheral venous administration of QW3600 injection (EchoGen) its efficacy and side effects . J Am Soc Echocardiogr. 10:1997;11-24.
7. Grayburn P.A., Weiss J.L., Hack T.C., et al. Phase III multicenter trial comparing the efficacy of 2% dodecafluoropentane emulsion (EchoGen) and sonicated 5% human albumin (Albunex) as ultrasound contrast agents in patients with suboptical echocardiograms. J Am Coll Cardiol. 32:1998;230-236.
8. Feinstein S.B., Shah P.M., Bing R.J., et al. Microbubble dynamics visualized in the intact capillary circulation. J Am Coll Cardiol. 4:1984;595-600.
9. Keller M.K., Segal S.S., Kaul S., Duling B. The behavior of sonicated albumin microbubbles within the microcirculation a basis for their use during myocardial contrast echocardiography . Circ Res. 65:1989;458-467.
10. Jayaweera A.R., Edwards N., Glasheen W.P., Villaneuva F.S., Abbott R.D., Kaul S. In vivo myocardial kinetics of air-filled albumin microbubbles during myocardial contrast echocardiography comparison with radiolabeled red blood cells . Circ Res. 74:1994;1157-1165.
11. Ismail S., Jayaweera A.R., Camarano G., Gimple L.W., Powers E.R., Kaul S. Relation between air-filled albumin microbubble and red blood cell rheology in the human myocardium influence of echocardiographic systems and chest wall attenuation . Circulation. 94:1996;445-451.
12. Suzuki H., Schmid-Schönbein G.W., Suematsu M., et al. Impaired leukocyte-endothelial cell interaction in spontaneously hypertensive rats. Hypertension. 24:1994;719-727.
13. Schmid-Schönbein G.W., Murakami H. Blood flow in contracting arterioles. Int J Microcirc Clin Exp. 4:1985;311-328.
14. Slezak S.E., Horan P.K. Stable cell membrane labelling. Nature. 340:1989;167-168.
15. Slezak S.E., Horan P.K. Fluorescent in vivo tracking of hematopoietic cells. Part I. Technical considerations. Blood. 74:1989;2172-2177.
16. Samlowski W.E., Robertson B.A., Draper B.K., Prystas E., McGregor J.R. Effects of supravital fluorochromes used to analyze the in vivo homing of murine lymphocytes on cellular function. J Immunol Methods. 144:1991;101-105.
17. Ikomi F., Hanna G.K., Schmid-Schöbein G.W. Mechanism of colloidal particle uptake into the lymphatic system basic study with percutaneous lymphography . Radiology. 196:1995;107-113.
18. Grayburn P. Perflenapent emulsion (EchoGen) a new long acting phase-shift agent for contrast echocardiography . Clin Cardiol. 20:(Suppl 1):1997;112-118.
19. Main M.L., Escobar J.F., Hall S.A., Grayburn P. Safety and efficacy of QW7437, a new fluorocarbon-based echocardiographic contrast agent. J Am Soc Echocardiogr. 10:1997;798-804.
20. Robbin M.L., Eisenfeld A.J. Perflenapent emulsion a US contrast agent for diagnostic radiology - multicenter, double-blind comparison with a placebo . Radiology. 207:1998;717-722.
21. Schmid-Schönbein G.W., Usami S., Skalak R., Chien S. The interaction of leukocytes and erythrocytes in capillary and postcapillary vessels. Microvasc Res. 19:1980;45-70.
22. Ley K., Cerrito M., Arfors K.E. Sulfated polysaccharides inhibit leukocyte rolling in rabbit mesentery venules. Am J Physiol. 260:1991;H1667-H1673.
23. Palabrica T., Lobb R., Furie B.C., et al. Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets. Nature. 359:1992;848-851.
24. Villanueva F.S., Jankowski R.J., Manaugh C., Wagner W.R. Albumin microbubble adherence to human coronary endothelium implications for assessment of endothelial function using myocardial contrast echocardiography . J Am Coll Cardiol. 30:1997;689-693.
25. Iigo Y., Suematsu M., Higashida T., et al. Constitutive expression of ICAM-1 in rat microvascular system analyzed by laser confocal microscopy. Am J Physiol. 273:1997;H138-H147.
26. Mor-Avi V., Lang R.M., Robinson K.A., et al. Contrast echocardiographic quantification of regional myocardial perfusion validation with an isolated rabbit heart model . J Am Soc Echocardiogr. 9:1996;156-165.
27. Clark L.C. Jr, Gollan F. Survival of mammals breathing organic liquids equilibrated with oxygen at atmospheric pressure. Science. 152:1966;1755-1756.
28. Sobin S.S., Tremer H.M. Three-dimensional organization of microvascular beds as related to function. Kaley G., Altura B.M. Microcirculation. 1977;43-67 University Park Press, Baltimore (MD).
29. 2 gradients . Microvasc Res. 12:1976;259-274.
30. Bassingthwaighte J.B., Yipintsoi T., Harvey R.B. Microvasculature of the dog left ventricular myocardium. Microvasc Res. 7:1974;229-249.
31. Nellis S., Toggart E. Cardiac microcirculation. Baker C.H., Nastuk W.L. Microcirculatory Technology. 1986;99-115 Academic Press, Orlando (FL).