Kinetics of GPIbα-vWF-A1 Tether Bond under Flow: Effect of GPIbα Mutations on the Association and Dissociation Rates

Biophysical Journal

Volumn 85, Issue 6, 2003, Pages 4099-4109

  Kumar, R Anand ^a   Dong, Jing Fei ^b   Thaggard, Jenny A ^b   Cruz, Miguei A ^b   López, José A ^b   McIntire, Larry V ^a,c  

^a Rice University   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYSTEINE; DISULFIDE; GLYCOPROTEIN IB; GLYCOPROTEIN IB ALPHA; SELECTIN; UNCLASSIFIED DRUG; VALINE; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR A1; FIBRINOGEN RECEPTOR; GLYCOPROTEIN RECEPTOR GPIB IX; GLYCOPROTEIN RECEPTOR GPIB-IX; THROMBIN RECEPTOR;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CALCULATION; CHO CELL; COMPLEX FORMATION; DISSOCIATION; FLOW; KINETICS; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SHEAR STRESS; ANIMAL; BIOLOGICAL MODEL; CELL DIVISION; CHEMISTRY; DOSE RESPONSE; FLOW CYTOMETRY; GENETIC TRANSFECTION; GENETICS; HAMSTER; IMAGE PROCESSING; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN TERTIARY STRUCTURE; THROMBOCYTE; TIME;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; TRIXIS;

AMINO ACID SEQUENCE; ANIMALS; BLOOD PLATELETS; CELL DIVISION; CHO CELLS; CRICETINAE; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; IMAGE PROCESSING, COMPUTER-ASSISTED; KINETICS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS; TRANSFECTION; VON WILLEBRAND FACTOR;

EID: 0345412698     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(03)74822-X     Document Type: Article

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