Localization of prostaglandin-H synthase-1 and -2 in mouse skin: Implications for cutaneous function

Experimental Cell Research

Volumn 242, Issue 1, 1998, Pages 84-91

  Muller Decker K ^a   Scholz, K ^b   Neufang, G ^a   Marks, F ^a   Furstenberger G ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Epidermis; Hyperplasia; Keratinocyte; Prostaglandin H synthase

Indexed keywords

CALCIUM ION; ISOENZYME; PROSTAGLANDIN SYNTHASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS MEMBRANE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; EPIDERMIS; EPIDERMIS HYPERPLASIA; FEMALE; HAIR FOLLICLE; IMMUNOREACTIVITY; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN; TISSUE DISTRIBUTION;

EID: 0345337249     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4068     Document Type: Article

References (22)

1. Goetzl, E. J., An, S., and Smith, W. L. (1995). Specific expression and effects of eicosanoid mediators in normal physiology and human diseases. FASEB J. 9, 1051-1058.
2. Fürstenberger, G., and Marks, F. (1990). Eicosanoids in normal and neoplastic growth. In "Eicosanoids and the Skin" (T. Ruzicka, Ed.), pp. 107-124, CRC Press, Boca Raton, FL.
3. Fürstenberger, G., and Marks, F. (1980). Early prostaglandin E synthesis is an obligatory event in the induction of cell proliferation in mouse epidermis in vivo by the phorbol ester TPA. Biochem. Biophys. Res. Commun. 92, 749-756.
4. Pentland, A. P., and Needleman, P. (1986). Modulation of keratinocyte proliferation in vitro by endogenous prostaglandin synthesis. J. Clin. Invest. 77, 246-251.
5. Scholz, K., Fürstenberger, G., Müller-Decker, K., and Marks, F. (1995). Differential expression of prostaglandin H-synthase isoenzymes in normal and activated keratinocytes in vivo and in vitro. Biochem. J. 306, 263-269.
6. Müller-Decker, K., Scholz, K., Marks, F., and Fürstenberger, G. (1995). Differential expression of prostaglandin H-synthase isoenzymes during multistage carcinogenesis in mouse epidermis. Mol. Carcinog. 12, 31-41.
7. 2. J. Biol. Chem. 269, 13057-13060.
8. Herschman, H. R. (1994). Regulation of prostaglandin synthase-1 and prostaglandin synthase-2. Cancer Metastasis Rev. 13, 241-256.
9. Herschman, H. R. (1996). Prostaglandin synthase-2. Biochim. Biophys. Acta 1299, 241-256.
10. Seibert, K., Zhang, Y., Leahy, K. Hauser, S., Masferrer, J., Perkins, W., Lee, L., and Isakson, P. (1994). Pharmacological and biochemical demonstration of the role of cyclooxygease 2 in inflammation and pain. Proc. Natl. Acad. Sci. USA 91, 12013-12017.
11. Stoler, A. B., Stenback F., and Balmain, A. (1993). The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event. J. Cell Biol. 122, 1103-1117.
12. Fürstenberger, G., Gross, M., Schweizer, J., Vogt, I., and Marks, F. (1986). Isolation, characterization, and in vitro cultivation of subfractions of neonatal mouse keratinocytes: Effects of phorbol esters. Carcinogenesis 7, 1745-1753.
13. Hennings, H., Michael, D., Cheng, C., Steinert, P., Holbrook, K., and Yuspa, S. (1980). Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 19, 245-254.
14. Cameron, G. S., Baldwin, J. K., Jasheway, D. W., Patrick, K. E., and Fischer, S. M. (1990). Arachidonic acid metabolism varies with the state of differentiation in density gradient separated mouse epidermal cells. J. Invest. Dermatol. 94, 292-296.
15. Leong, J., Hughes-Fulford, M., Rakhlin, N., Habib, A., Maclouf, J., and Goldyne, M. E. (1996). Cyclooxygenases in human and mouse skin and cultured human keratinocytes: association of COX-2 expression with human keratinocyte differentiation. Exp. Cell Res. 224, 79-87.
16. Michelet, J.-F., Commo, S., Billoni, N., Mahe, Y. F., and Bernard, B. A. (1997). Activation of cytoprotective prostaglandin synthase-1 by minoxidil as a possible explanation for it's hair growth-stimulating effect. J. Invest. Dermatol. 108, 205-209.
17. Kujubu, D. A., Reddy, S. T., Fletcher, B. S., and Herschman, H. R. (1993). Expression of the protein product of the prostaglandin synthase-2/TIS 10 gene in mitogen-stimulated Swiss 3T3 cells. J. Biol. Chem. 268, 5425-5430.
18. Morita, I., Schindler, M., Regier, M. K. Otto, J. C., Hori, T., Dewitt, D. L., and Smith, W. L. (1995). Different intracellular locations for prostaglandin endoperoxide H synthases 1 and 2. J. Biol. Chem. 270, 10902-10908.
19. Coffey, R. J., Hawkey, C. J., Damstrup, L., Graves-Deal, R., Daniel, V. C., Dempsey, P. J., Chinery, R., Kirkland, S. C., DuBois, R. N., Jetton, T. L., and Morrow, J. D. (1997). Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells. Proc. Natl. Acad. Sci. USA 94, 657-662.
20. Fürstenberger, G., Gross, M., and Marks, F. (1989). Eicosanoids and multistage carcinogenesis in NMRI mouse skin: role of prostaglandins E and F in conversion (first stage of tumor promotion) and promotion (second stage of tumor promotion). Carcinogenesis 10, 91-96.
21. Müller-Decker, K., Seibert, K., Kopp-Schneider, A., Marks, F., and Fürstenberger, G. (1997). Chemoprevention of skin tumor development in mice by the specific PGHS-2 inhibitor SC58125. (submitted for publication).
22. 2 that mediates prostaglandin production in mast cells. J. Biol. Chem. 272, 13591-13596.