Activation of visceral afferents by bradykinin and ischemia: Independent roles of PKC and prostaglandins

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 276, Issue 6 45-6, 1999, Pages

  Zhi Ling, Guo ^a   Symons, J David ^b   Longhurst, John C ^a   Longhurst, J C ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

Cat; Nociception; Phosphoinositide system; Protein kinase C; Sympathetic afferents

Indexed keywords

BRADYKININ; INDOMETACIN; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE C;

ADRENERGIC TRANSMISSION; ANIMAL EXPERIMENT; ARTICLE; CAT; ENZYME ACTIVITY; FEMALE; MALE; NOCICEPTIVE STIMULATION; NONHUMAN; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SENSORY NERVE; SENSORY STIMULATION;

EID: 0345280715     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.276.6.h1884     Document Type: Article

References (30)

1. Bevan, S. Intracellular messengers and signal transduction in nociceptors. In: Neurobiology of Nociceptors, edited by C. Belmonte. New York: Oxford, 1996, p. 298-324.
2. Bhoola, K. D., C. D. Figueroa, and K. Worthy. Bioregulation of kinins: kallikreins, kininogens, and kininases. Pharmacol. Rev. 44: 1-80, 1992.
3. Burch, R. M. Protein kinase C mediates endotoxin and zymosan-induced prostaglandin synthesis. Eur. J. Pharmacol. 142: 431-435, 1987.
4. Burgess, G. M., I. Mullaney, M. McNeill, P. M. Dunn, and H. P. Rang. Second messengers involved in the mechanism of action of bradykinin in sensory neurons in culture. J. Neurosci. 9: 3314-3325, 1989.
5. 2 receptors contribute to reflex cardiovascular responses during brief abdominal ischemia. Am. J. Physiol. 274 (Heart Circ. Physiol. 43): H308-H313, 1998.
6. Church, D. J., V. Van der Bent, M. B. Vallotton, and U. Lang. Role of prostaglandin-mediated cyclic AMP formation in protein kinase C-dependent secretion of atrial natriuretic peptide in rat cardiomyocytes. Biochem. J. 303: 217-225, 1994.
7. Clark, S., R. Keogh, and M. Dunlop. The role of protein kinase C in arachidonic acid release and prostaglandin E production from CHO cells transfected with EGF receptors. Biochim Biophys Acta 1224: 221-227, 1994.
8. Fischer, S. M., K. E. Patrick, M. L. Lee, and G. S. Cameron. Four-β-and 4-α-12-o-tetradecanoylphorbol-13-acetate elicit arachidonate release from epidermal cells through different mechanisms. Cancer Res. 51: 850-856, 1991.
9. 3 receptors in activation abdominal sympathetic C fibre afferents during ischemia in cats. J. Physiol. 509: 729-740, 1998.
10. 1 receptors. Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H2726-H2737, 1997.
11. Gammon, C. M., A. C. Allen, and P. Morell. Bradykinin stimulates phosphoinositide hydrolysis and mobilization of arachidonic acid in dorsal root ganglion neurons. J. Neurochem. 53: 95-101, 1989.
12. 2 in rat renal mesangial cells. J. Biol. Chem. 263: 16645-16651, 1988.
13. Guo, Z.-L., L.-W. Fu, J. D. Symons, and J. C. Longhurst. Signal transduction in activation of ischemically sensitive abdominal visceral afferents: role of PKC. Am. J. Physiol. 275 (Heart Circ. Physiol. 44): H1024-H1031, 1998.
14. Guo, Z.-L., J. D. Symons, and J. C. Longhurst. Bradykinin-mediated activation of ischemically sensitive abdominal visceral afferents: contributions from the phosphoinositide and cyclooxygenase pathways. Soc. Neurosci. Abstr. 24: 871, 1998.
15. 2 activity. J. Biol. Chem. 262: 11764-11770, 1987.
16. Kellner, R. G., and G. Van der Kraak. Multifactorial regulation of prostaglandin synthesis in preovulatory goldfish ovarian follicles. Biol. Reproduct. 46: 630-635, 1992.
17. Kopp, U. C., and L. A Smith. A role for protein kinase C in bradykinin-mediated activation of renal pelvic sensory receptors. Am. J. Physiol. 269 (Regulatory Integrative Comp. Physiol. 38): R331-R338, 1995.
18. 2 by diacylglycerol. Biochem. J. 248: 779-783, 1987.
19. Longhurst, J. C. Chemosensitive abdominal visceral afferents, In: Visceral Pain, Progress in Pain Research and Management, edited by G. F. Gebhart. Seattle, WA: Int. Assoc. for the Study of Pain, 1995, vol. 5, p. 99-132.
20. Longhurst, J. C., and L. E. Dittman. Hypoxia, bradykinin and prostaglandins stimulate ischemically sensitive visceral afferents. Am. J. Physiol. 253 (Heart Circ. Physiol. 22): H556-H567, 1987.
21. Longhurst, J. C., D. M. Rotto, M. P. Kaufman, and G. L. Stahl. Ischemically sensitive abdominal visceral afferents: response to cyclooxygenase blockade. Am. J. Physiol. 261 (Heart Circ. Physiol. 30): H2075-H2081, 1991.
22. Mahoney, C. W., and K.-P. Huang. Molecular and catalytic properties of protein kinase C. In: Protein Kinase C, edited by J. F. Kuo. New York: Oxford, 1994, p. 16-63.
23. 2 receptors. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H2398-H2460, 1994.
24. Parker, J., L. W. Daniel, and M. Waite. Evidence of protein kinase C involvement in phorbol diester-stimulated arachidonic acid release and prostaglandin synthesis. J. Biol. Chem. 262: 5385-5393, 1987.
25. Quest, A. F. G., and R. M. Bell. The molecular mechanism of protein kinase C regulation by lipids. In: Protein Kinase C, edited by J. F. Kuo. New York: Oxford, 1994, p. 64-95.
26. + derived from lactic acid and hypercapnia. Am. J. Physiol. 262 (Heart Circ. Physiol. 31): H748-H753, 1992.
27. Stahl, G. L., H.-L. Pan, and J. C. Longhurst. Activation of ischemia and reperfusion-sensitive abdominal visceral C fiber afferents: role of hydrogen peroxide and hydroxyl radicals. Circ. Res. 72: 1266-1275, 1993.
28. 2 activation by bradykinin and its regulation by protein kinase C and calcium. Nippon Seikeigeka Gakkai Zasshi. J. Jap. Orthopaedic Assoc. 67: 935-943, 1993.
29. Thore, C. R., M. Nam, and D. Busija. Phorbol ester-induced prostaglandin production in piglet cortical astroglia. Am. J. Physiol. 267 (Regulatory Integrative Comp. Physiol. 36): R34-R37, 1994.
30. 2 activation in Madin-Darby canine kidney cells. J. Biol. Chem. 266: 2126-2133, 1991.