Signal transduction in activation of ischemically sensitive abdominal visceral afferents: Role of PKC

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 275, Issue 3 44-3, 1998, Pages

  Quo, Zhi Ling ^a,b   Fu, Liang Wu ^a   David Symons, J ^a   Longhurst, John C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Abdominal ischemia; Cat; Nociception; Phorbol ester; Sympathetic afferents

Indexed keywords

BRADYKININ; PHORBOL DIBUTYRATE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR;

ABDOMEN; ANIMAL EXPERIMENT; ARTICLE; CARDIOVASCULAR RESPONSE; CAT; CONTROLLED STUDY; FEMALE; ISCHEMIA; MALE; MESENTERIC ARTERY OCCLUSION; NERVE FIBER C; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; SENSORY NERVE; SIGNAL TRANSDUCTION; VISCERA;

EID: 20644469227     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1998.275.3.h1024     Document Type: Article

References (17)

1. Ahlgren, S. C., and J. D. Levine. Protein kinase C inhibitors decrease hyperalgesia and C-fiber hyperexcitability in the streptozotocin-diabetic rat. J. Neurophysiol. 72: 684-692, 1994.
2. Bevan, S. Intracellular messengers and signal transduction in nociceptors. In: Neurobiology of Nociceptors, edited by C. Belmonte. New York: Oxford, 1996, p. 289-324.
3. Boland, L. M., A. C. Allen, and R. Dingledine. Inhibition by bradykinin of voltage-activated barium current in a rat dorsal root ganglion cell line: role of protein kinase C. J. Neurosci. 11: 1140-1149, 1991.
4. Burgess, G. M., I. Mullaney, M. McNeil, P. M. Dunn, and H. P. Rang. Second messengers involved in the action of bradykinin on cultured sensory neurons. J. Neurosci. 9: 3314-3325, 1989.
5. Chuang, D. M. Neurotransmitter receptors and phosphoinositide turnover. Annu. Rev. Pharmacol. Toxicol. 29: 71-110, 1989.
6. Conn, P. J., and J. D. Sweatt. Protein kinase C in the nervous system. In: Protein Kinase C, edited by J. F. Kuo. New York: Oxford, 1994, p. 199-235.
7. Dray, A., J. Bettaney, P. Forster, and M. N. Perkins. Bradykinin-induced stimulation of afferent fibers is mediated through protein kinase C. Neurosci. Lett. 91: 301-307, 1988.
8. 1 receptors. Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H2726-H2737, 1997.
9. 3 receptors. Soc. Neurosci. Abstr. 22: 1801, 1996.
10. Garcia-Sainz, J. A. Cell responsiveness and protein kinase C: receptors, G proteins, and membrane effectors. News Physiol. Sci. 6: 169-173, 1991.
11. Guo, Z.-L., J. D. Symons, L.-W. Fu, and J. C. Longhurst. Protein kinase C contributes to bradykinin-mediated activation of ischemically sensitive abdominal visceral afferents (Abstract). FASEB J. 12: A689, 1998.
12. Hardie, D. G. Cellular functions of protein kinases. In: The Protein Kinase Facts Book: Protein-Serine Kinases, edited by G. Hardie and S. Hanks. London/San Diego: Academic, 1995, p. 48-56.
13. House, C., and B. E. Kemp. Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science 238: 1726-1728, 1987.
14. Kaczmarek, L. K. The role of protein kinase C in the regulation of ion channels and neurotransmitter release. Trends Neurosci. 10: 30-34, 1987.
15. Kikkawa, U., and Y. Nishizuka. The role of protein kinase C in transmembrane signalling. Annu. Rev. Cell Biol. 2: 149-178, 1986.
16. Kopp, U. C., and L. A Smith. A role for protein kinase C in bradykinin-mediated activation of renal pelvic sensory receptors. Am. J. Physiol. 269 (Regulatory Integrative Comp. Physiol. 38): R331-R338, 1995.
17. Leach, K. L., and P. M. Blumberg. Tumour promoters, their receptors and their actions. In: Inositol Lipids in Cell Signalling, edited by R. H. Michell, A. H. Drummond, and C. P. Downes. New York: Academic, 1989, p. 179-205.