Suppression of the hyperpolarization-activated inward current contributes to the inhibitory actions of propofol on rat CA1 and CA3 pyramidal neurons

Neuroscience Research

Volumn 45, Issue 4, 2003, Pages 459-472

  Higuchi, Hitoshi ^a   Funahashi, Makoto ^a   Miyawaki, Takuya ^a   Mitoh, Yoshihiro ^a   Kohjitani, Atsushi ^a   Shimada, Masahiko ^a   Matsuo, Ryuji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Brain slice; IH; Propofol; Rats

Indexed keywords

4 (N ETHYL N PHENYLAMINO) 1,2 DIMETHYL 6 (METHYLAMINO)PYRIMIDINIUM CHLORIDE; 4 AMINOBUTYRIC ACID A RECEPTOR; PICROTOXIN; PROPOFOL;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DRUG MECHANISM; ELECTRIC POTENTIAL; EPILEPTIC DISCHARGE; HIPPOCAMPUS; HYPERPOLARIZATION; MALE; MEMBRANE CHANNEL; MEMBRANE CURRENT; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

EID: 0345268781     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(03)00003-8     Document Type: Article

References (37)

1. A-mediated inhibition in the rat hippocampal slice. Life Sci. 58:1996;2397-2407.
2. Biel M., Ludwig A., Zong X., Hofmann F. Hyperpolarization-activated cation channels: a multi-gene family. Rev. Physiol. Biochem. Pharmacol. 136:1999;165-181.
3. f) in guinea-pig dissociated sinoatrial node cells. Br. J. Pharmacol. 110:1993;343-349.
4. Cockshott I.D. Propofol ('Diprivan') pharmacokinetics and metabolism - an overview. Postgrad. Med. J. 61:(Suppl. 3):1985;45-50.
5. Collins G.G. Effects of the anaesthetic 2,6-diisopropylphenol on synaptic transmission in the rat olfactory cortex slice. Br. J. Pharmacol. 95:1988;939-949.
6. DeFriez C.B., Wong H.C. Seizures and opisthotonos after propofol anesthesia. Anesth. Analg. 75:1992;630-632.
7. Dickson C.T., Magistretti J., Shalinsky M.H., Fransen E., Hasselmo M.E., Alonso A. Properties and role of I (h) in the pacing of subthreshold oscillations in entorhinal cortex layer II neurons. J. Neurophysiol. 83:2000;2562-2579.
8. Friederich P., Benzenberg D., Urban B.W. Ketamine and propofol differentially inhibit human neuronal K(+) channels. Eur. J. Anaesthesiol. 18:2001;177-183.
9. Funahashi M., Stewart M. Presubicular and parasubicular cortical neurons of the rat: functional separation of deep and superficial neurons in vitro. J. Physiol. Lond. 501:1997;387-403.
10. Funahashi M., Stewart M. Properties of gamma-frequency oscillations initiated by propagating population bursts in retrohippocampal regions of rat brain slices. J. Physiol. Lond. 510:1998;191-208.
11. Funahashi M., Higuchi H., Miyawaki T., Shimada M., Matsuo R. Propofol suppresses a hyperpolarization-activated inward current in rat hippocampal CA1 neurons. Neurosci. Lett. 311:2001;177-180.
12. Ghamari-Langroudi M., Bourque C.W. Excitatory role of the hyperpolarization-activated inward current in phasic and tonic firing of rat supraoptic neurons. J. Neurosci. 20:2000;4855-4863.
13. Hales T.G., Lambert J.J. The actions of propofol on inhibitory amino acid receptors of bovine adrenomedullary chromaffin cells and rodent central neurones. Br. J. Pharmacol. 104:1991;619-628.
14. Halliwell J.V., Adams P.R. Voltage-clamp analysis of muscarinic excitation in hippocampal neurons. Brain Res. 250:1982;71-92.
15. A receptor-chloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat. Anesthesiology. 79:1993;781-788.
16. Inoue Y., Shibuya I., Kabashima N., Noguchi J., Harayama N., Ueta Y., Sata T., Shigematsu A., Yamashita H. The mechanism of inhibitory actions of propofol on rat supraoptic neurons. Anesthesiology. 91:1999;167-178.
17. Kazama T., Ikeda K., Morita K. The pharmacodynamic interaction between propofol and fentanyl with respect to the suppression of somatic or hemodynamic responses to skin incision, peritoneum incision, and abdominal wall retraction. Anesthesiology. 89:1998;894-906.
18. Kurokawa H., Murray P.A., Damron D.S. Propofol attenuates beta-adrenoreceptor-mediated signal transduction via a protein kinase C-dependent pathway in cardiomyocytes. Anesthesiology. 96:2002;688-698.
19. Luthi A., McCormick D.A. H-current: properties of a neuronal and network pacemaker. Neuron. 21:1998;9-12.
20. H normalizes temporal summation in hippocampal CA1 neurons. Nat. Neurosci. 2:1999;508-514.
21. Makela J.P., Iivanainen M., Pieninkeroinen I.P., Waltimo O., Lahdensuu M. Seizures associated with propofol anesthesia. Epilepsia. 34:1993;832-835.
22. McCormick D.A., Pape H.C. Properties of a hyperpolarization-activated cation current and its role in rhythmic oscillation in thalamic relay neurones. J. Physiol. Lond. 431:1990;291-318.
23. Nagao T., Alonso A., Avoli M. Epileptiform activity induced by pilocarpine in the rat hippocampal-entorhinal slice preparation. Neuroscience. 72:1996;399-408.
24. A receptors in cultured murine hippocampal neurons. J. Neurosci. 14:1994;7747-7760.
25. Orser B.A., Bertlik M., Wang L.Y., MacDonald J.F. Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl-D-aspartate subtype of glutamate receptor in cultured hippocampal neurones. Br. J. Pharmacol. 116:1995;1761-1768.
26. O'Shea S.M., Wong L.C., Harrison N.L. Propofol increases agonist efficacy at the GABA(A) receptor. Brain Res. 852:2000;344-348.
27. Pape H.C. Queer current and pacemaker: the hyperpolarization-activated cation current in neurons. Annu. Rev. Physiol. 58:1996;299-327.
28. Peduto V.A., Concas A., Santoro G., Biggio G., Gessa G.L. Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain. Anesthesiology. 75:1991;1000-1009.
29. Rehberg B., Duch D.S. Suppression of central nervous system sodium channels by propofol. Anesthesiology. 91:1999;512-520.
30. Shafer A., Doze V.A., Shafer S.L., White P.F. Pharmacokinetics and pharmacodynamics of propofol infusions during general anesthesia. Anesthesiology. 69:1988;348-356.
31. Sirois J.E., Pancrazio J.J., Iii C.L., Bayliss D.A. Multiple ionic mechanisms mediate inhibition of rat motoneurones by inhalation anaesthetics. J. Physiol. Lond. 512:1998;851-862.
32. Smith C., McEwan A.I., Jhaveri R., Wilkinson M., Goodman D., Smith L.R., Canada A.T., Glass P.S. The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision. Anesthesiology. 81:1994;820-828.
33. Thoby-Brisson M., Telgkamp P., Ramirez J.M. The role of the hyperpolarization-activated current in modulating rhythmic activity in the isolated respiratory network of mice. J. Neurosci. 20:2000;2994-3005.
34. Thomas J.S., Boheimer N.O. An isolated grand mal seizure 5 days after propofol anaesthesia. Anaesthesia. 46:1991;508.
35. Tokimasa T., Sugiyama K., Akasu T., Muteki T. Volatile anaesthetics inhibit a cyclic AMP-dependent sodium-potassium current in cultured sensory neurones of bullfrog. Br. J. Pharmacol. 101:1990;190-192.
36. Williams J.H., Kauer J.A. Properties of carbachol-induced oscillatory activity in rat hippocampus. J. Neurophysiol. 78:1997;2631-2640.
37. Yamakura T., Sakimura K., Shimoji K., Mishina M. Effects of propofol on various AMPA-, kainate- and NMDA-selective glutamate receptor channels expressed in Xenopus oocytes. Neurosci. Lett. 188:1995;187-190.