Preclinical pharmacology of B-20991, a 5-HT(1A) receptor agonist with anxiolytic activity

European Journal of Pharmacology

Volumn 344, Issue 2-3, 1998, Pages 127-135

  Beneytez, María E ^a   López Rodríguez, María L ^b   Rosado, María L ^b   Morcillo, María J ^b   Orensanz, Luis ^c   Fuentes, José A ^a   Manzanares, Jorge ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

5 HT(1A) receptor agonist; Anxiolytic; Behavior, 8 OH DPAT (8 hydroxy 2 (di n propylamino)tetralin); Hypothermia

Indexed keywords

2 [[4 (ORTHO METHOXYPHENYL)PIPERAZIN 1 YL]METHYL] 1,3 DIOXOPERHYDROIMIDAZO[1,5 A]PYRIDINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3,4 DIHYDROXYPHENYLACETIC ACID; 5 HYDROXYINDOLEACETIC ACID; ALPHA 1 ADRENERGIC RECEPTOR; B 20991; BENZODIAZEPINE RECEPTOR; DOPAMINE; DOPAMINE 2 RECEPTOR; SEROTONIN; SEROTONIN 1A AGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 3 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BINDING SITE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG RECEPTOR BINDING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIGHT DARK CYCLE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SOCIAL INTERACTION; SUBCUTANEOUS DRUG ADMINISTRATION; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; BEHAVIOR, ANIMAL; BODY TEMPERATURE; IMIDAZOLES; LOCOMOTION; MALE; MICE; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN AGONISTS;

EID: 0345267410     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01583-5     Document Type: Article

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