Estradiol modulates acetylcholine-induced Ca2+ signals in LHRH-releasing GT1-7 cells through a membrane binding site

European Journal of Neuroscience

Volumn 18, Issue 9, 2003, Pages 2505-2514

  Morales, Araceli ^a,c   Díaz, Mario ^a   Ropero, Ana B ^b,c   Nadal, Angel ^b   Alonso, Rafael ^a  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

^b MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute estrogen effects; Calcium homeostasis; Estrogen membrane receptors; Neurosecretion

Indexed keywords

ACETYLCHOLINE; CALCIUM; ESTRADIOL; FULVESTRANT; GONADORELIN; PROGESTERONE; TAMOXIFEN;

ANIMAL CELL; ARTICLE; BINDING SITE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HYPOTHALAMUS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACETYLCHOLINE; ANIMALS; CALCIUM CHANNELS; CALCIUM SIGNALING; CELL LINE, TUMOR; ESTRADIOL; ESTROGEN RECEPTOR MODULATORS; GONADOTROPIN-RELEASING HORMONE; MICE; MICE, TRANSGENIC; PEROXIDASES; RECEPTORS, MUSCARINIC;

EID: 0345257777     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2003.02997.x     Document Type: Article

References (40)

1. Ábrahám, I.M., Han, S.-K., Todman, M.G., Korach, K.S. & Herbison, A.E. (2003) Estrogen receptor β mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo. J. Neurosci., 23, 5771-5777.
2. Berridge, M.J., Downes, C.P. & Hanley, M.R. (1982) Lithium amplifies agonist-dependent phosphatidyl-inositol responses in brain and salivary glands. Biochem. J., 206, 587-595.
3. Butler, J. A., Sjöberg, M. & Coen, C.W. (1999) Evidence for oestrogen receptor α-immunoreactivity in gonadotrophin-releasing hormone-expressing neurones. J. Neuroendocrinol., 11, 331-335.
4. Condon, T.P., Dykshoorn-Bosch, M.A. & Kelly, M.J. (1988) Episodic luteinizing-hormone release in the ovariectomized female guinea pig: rapid inhibition by estrogen. Biol. Reprod., 38, 121-126.
5. I in female rat distal colon. Mol. Cell. Endocrinol., 199, 87-103.
6. Everett, J.W., Sawyer, C.H. & Markee, I.E. (1949) A neurogenic timing factor in the control of the ovulatory discharge of luteinizing hormone in the cyclic rat. Endocrinology, 44, 234-250.
7. Freeman, M.E. (1994) The neuroendocrine control of the ovarian cycle in the rat. In Knobil, E. & Neill, J.D. (eds) The Physiology of Reproduction. Raven Press, New York, pp. 613-658.
8. Herbison, A.E. (1998) Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons. Endocr. Rev., 19, 302-330.
9. Herbison, A.E., Robinson, J.E. & Kinner, D.C. (1993) Distribution of estrogen receptor immunoreactive cells in the preoptic area of the ewe: co-localization with glutamic acid decarboxylase but not luteinizing hormone-releasing hormone and estrogen receptor immunoreactivity in the guinea-pig brain. Neuroendocrinology, 57, 751-759.
10. Ho, K.J. & Liao, J.K. (2002) Nonnuclear actions of estrogen. Arterioscler. Thromb. Vasc. Biol., 22, 1952-1961.
11. Hrabovszky, E., Steinhauser, A., Barabás, K., Shughrue, P.J., Petersen, S.L., Merchenthaler, I. & Liposits, Z. (2001) Estrogen receptor-β immunoreactivity in luteinizing hormone-releasing hormone neurons of the rat brain. Endocrinology, 142, 3261-3264.
12. + channel activity in hypothalamic neurons involved in the control of the reproductive axis. Steroids, 67, 447-456.
13. Krsmanovic, L.Z., Mores, N., Navarro, C.E., Saeed, A.S., Arora, K.K. & Catt, K.J. (1998) Muscarinic regulation of intracellular signaling and neurosecretion in gonadotropin-releasing hormone neurons. Endocrinology, 139, 4037-4043.
14. Kuiper, G.G.J.M., Carlsson, B., Grandien, K., Enmark, E., Häggblad, J., Nilsson, S. & Gustafsson, J.-Å. (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology, 138, 863-870.
15. Lagrange, A.H., Ronnkleiv, O.K. & Kelly, M.J. (1995) Estradiol-17β and μ-opioid peptides rapidly hyperpolarize GnRH neurons: a cellular mechanism of negative feedback. Endocrinology, 136, 2341-2344.
16. Libertum, C. & McCann, S.M. (1973) Blockade of the release of gonadotropins and prolactin by subcutaneous or intraventricular injection of atropine in male and female rats. Endocrinology, 92, 1714-1724.
17. Losel, R.M., Falkenstein, E., Feuring, M., Schultz, A., Tillman, H.-C., Rossol-Haseroth, K. & Wehling, M. (2003) Nongenomic steroid action: controversies, questions ad answers. Physiol. Rev., 83, 965-1016.
18. Martínez-Morales, L.R., Morales, A., Marin, R., Hernández-Liménez, L.G., Acevedo, A., Guerra, B., Hernández, G., Lopez-Coviella, I., Prieto, L. & Alonso, R. (2001) Estrogen modulates norepinephrine-induced accumulation of adenosine cyclic monophosphate in a subpopulation of immortalized luteinizing hormone-releasing hormone secreting neurons from the mouse hypothalamus. Neurosci. Lett., 298, 61-64.
19. Mellon, P.L., Windle, L.J., Goldsmith, P.C., Padula, C.A., Roberts, L.L. & Weiner, R.J. (1990) Immortalization of hypothalamic GnRH neurons by genetically targeted tumoregenesis. Neuron, 5, 1-10.
20. Mermelstein, P.G., Becker, L.B. & Surmeier, D.J. (1996) Estradiol reduces calcium currents in rat neostriatal neurons via a membrane receptor. J. Neurosci., 16, 595-604.
21. Nadal, A., Díaz, M. & Valverde, M.A. (2001) The estrogen trinity: membrane, cytosolic, and nuclear effects. News Physiol. Sci., 16, 251-255.
22. Nadal, A., Ropero, A.B., Laribi, O., Maillet, M., Fuentes, E. & Soria, B. (2000) Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor α and estrogen receptor β. Proc. Natl. Acad. Sci. USA, 97, 11603-11608.
23. Navarro, C.E., Abdul Saeed, S., Murdock, C., Martinez-Fuente, K.K., Krsmanovic, L.Z. & Cat, K.J. (2003) Regulation of cyclic AMP signalling and pulsatile neurosecretion by Gi-coupled plasma membrane E receptors in immortalized GnRH neurons. Mol Endocrinol., 17, 1792-1804.
24. Nilsen, J. & Diaz-Brinton, R. (2003) Mechanism of estrogen-mediated neuro-protection: Regulation of mitocondrial calcium and BCL-2 expression. Proc. Natl. Acad. Sci. USA, 100, 2842-2847.
25. Nunemaker, C.S., Defazio, R.A., Geusz, M.E., Herzog, E.D., Pitts, G.R. & Moenter, S.M. (2001) Long-term recordings of networks of immortalized GnRH neurons reveal episodic patterns of electrical activity. J. Physiol. (Lond.), 86, 86-93.
26. Nuñez, L., Faught, W.J. & Frawley, S. (1998) Episodic gonadotropin-releasing hormone gene expression revealed by dynamic monitoring of luciferase reporter activity in single, living neurons. Proc. Natl. Acad. Sci. USA, 95, 9648-9653.
27. Nuñez, L., Villalobos, C., Boockfor, F.R. & Frawley, L.S. (2000) The relationship between pulsatile secretion and calcium dynamics in single, living gonadotropin-releasing hormone neurons. Endocrinology, 141, 2012-2017.
28. Radovick, S., Ticknor, C.M., Nakyama, Y., Notides, A.C., Rahman, A., Weintraub, B.D., Cutler, G.B. & Wondisford, F.E. (1991) Evidence for direct estrogen regulation of the human gonadotropin-releasing hormone gene. J. Clin. Invest., 88, 1649-1655.
29. Radovick, S., Wray, S., Muglia, L., Westphal, H., Olsen, B., Smith, E., Patriquin, E. & Wondisfor, F.E. (1994) Steroid hormone regulation and tissue specific expression of the human GnRH gene in cell culture and transgenic animals. Horm. Behav., 28, 520-529.
30. Ropero, A.B., Fuentes, E., Rovira, J.M., Ripoll, C., Soria, B. & Nadal, A. (1999) Non-genomic actions of 17beta-oestradiol in mouse pancreatic beta-cells are mediated by a cGMP-dependent protein kinase. J. Physiol. (Lond.), 521, 397-407.
31. Ropero, A.B., Soria, B. & Nadal, A. (2002) A nonclassical estrogen membrane receptor triggers rapid differential actions in the endocrine pancreas. Mol. Endocrinol., 16, 497-605.
32. Sandmann, J. & Wurtman, R.J. (1991) Stimulation of phospholiphase D activity in human neuroblastoma (LA-N-2) cells by activation of muscarinic acetylcholine receptors or by phorbol esters: Relationship to phosphoinositide turnover. J. Neurochem., 56, 1312-1319.
33. Sarkar, D.K. & Fink, G. (1980) Luteinizing hormone releasing factor in pituitary stalk plasma from long-term ovariectomized rats: effects of steroids. J. Endocrinol., 86, 511-524.
34. Shen, E.S., Meade, E.H., Pérez, M.C., Deecher, D.C., Negro-Vilar, A. & López, F.J. (1998) Expression of functional estrogen receptors and galanin messenger ribonucleic acid in immortalized luteinizing hormone-releasing hormone neurons: estrogenic control of galanin gene expression. Endocrinology, 139, 939-948.
35. Shivers, B.D., Harlan, R.E., Morrel, J.I. & Pfaff, D.W. (1983) Absence of estradiol concentration in cell nuclei of LHRH-immunoreactive neurons. Nature, 304, 345-347.
36. Sullivan, K.A., Witkin, J.W., Ferin, M. & Silverman, A.-J. (1995) Gonadotrophin-releasing hormone neurons in the rhesus macaque are non-immunoreactive for the estrogen receptor. Brain. Res., 685, 198-200.
37. Valverde, M.A., Rojas, P., Amigo, J., Cosmelli, D., Orio, P., Bahamonde, M.I., Mann, G.E., Vergara, C. & Latorre, R. (1999) Acute activation of Maxi-K channels (hSlo) by estradiol binding to the β subunit. Science, 285, 1929-1931.
38. Vazquez-Martínez, R., Shorte, S.L., Faught, W.J., Leaumoint, D.C., Frawley, L.S. & Boockfor, F.R. (2001) Pulsatile exocytosis is functionally associated with GnRH gene expression in immortalized GnRH-expressing cells. Endocrinology, 142, 5364-5370.
39. Wetsel, W.C., Valenca, M.M., Merchenthaler, I., Liposits, Z., Lopez, F.J., Weiner, R.I., Mellon, P.L. & Negro-Vilar, A. (1992) Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons. Proc. Natl. Acad. Sci. USA, 89, 4149-4153.
40. Yamaji, T., Dierschke, D.J., Bhattacharya, A.N. & Knobil, E. (1972) The negative feedback control by estradiol and progesterone of LH secretion in the ovariectomized rhesus monkey. Endocrinology, 90, 771-777.