Human Spot 14 Glucose and Thyroid Hormone Response: Characterization and Thyroid Hormone Response Element Identification

Endocrinology

Volumn 144, Issue 12, 2003, Pages 5242-5248

  Campbell, Mark C ^a   Anderson, Grant W ^a   Mariash, Cary N ^a,b  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; DNA FRAGMENT; GLUCOSE; M PROTEIN; RETINOID X RECEPTOR; SPOT 14; THYROID HORMONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHROMOSOMAL LOCALIZATION; DNA BINDING; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSCRIPTION; HORMONE RESPONSE; HUMAN; HUMAN CELL; MALE; NONHUMAN; OBESITY; ORTHOLOGY; PRIORITY JOURNAL; PROMOTER REGION; RAT; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STATISTICAL SIGNIFICANCE; TRANSCRIPTION REGULATION;

ANIMALS; CELLS, CULTURED; GLUCOSE; HEPATOCYTES; HUMANS; MALE; MUTAGENESIS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RESPONSE ELEMENTS; SPECIES SPECIFICITY; THYROID HORMONES; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 0345257114     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2002-0008     Document Type: Article

References (25)

1. Oppenheimer JH, Kinlaw WB, Wong NC, Schwartz HL, Mariash CN 1987 Regulation of gene S-14 by triiodothyronine in liver. Horm Metab Res Suppl 17:1-5
2. Seelig S, Liaw C, Towle HC, Oppenheimer JH 1981 Thyroid hormone attenuates and augments hepatic gene expression at a pretranslational level. Proc Natl Acad Sci USA 78:4733-4737
3. Brown SB, Maloney M, Kinlaw WB 1997 "Spot 14" protein functions at the pretranslational level in the regulation of hepatic metabolism by thyroid hormone and glucose. J Biol Chem 272:2163-2166
4. Kinlaw WB, Church JL, Harmon J, Mariash CN 1995 Direct evidence for a role of the "spot 14" protein in the regulation of lipid synthesis. J Biol Chem 270:16615-16618
5. Zou L, Hagen SG, Strait KA, Oppenheimer JH 1994 Identification of thyroid hormone response elements in rodent Pcp-2, a developmentally regulated gene of cerebellar Purkinje cells. J Biol Chem 269:13346-13352
6. Chin WW 1994 Molecular mechanisms of thyroid hormone action. Thyroid 4:389-393
7. Brent GA, Harney JW, Chen Y, Warne RL, Moore DD, Larsen PR 1989 Mutations of the rat growth hormone promoter which increase and decrease response to thyroid hormone define a consensus thyroid hormone response element. Mol Endocrinol 3:1996-2004
8. Zilz ND, Murray MB, Towle HC 1990 Identification of multiple thyroid hormone response elements located far upstream from the rat S14 promoter. J Biol Chem 265:8136-8143
9. Ota Y, Mariash A, Wagner JL, Mariash CN 1997 Cloning, expression and regulation of the human S14 gene. Mol Cell Endocrinol 126:75-81
10. Moncur JT, Park JP, Memoli VA, Mohandas TK, Kinlaw WB 1998 The "Spot 14" gene resides on the telomeric end of the 11q13 amplicon and is expressed in lipogenic breast cancers: implications for control of tumor metabolism. Proc Natl Acad Sci USA 95:6989-6994
11. Bruford EA, Ruse R, Teague PW, Porter K, Thomson KL, Moore AT, Jay M, Warburg M, Schinzel A, Tommerup N, Tornqvist K, Rosenberg T, Patton M, Mansfield DC, Wright AF 1997 Linkage mapping in 29 Bardet-Biedl syndrome families confirms loci in chromosomal regions 11q13, 15q22.3-q23, and 16q21. Genomics 41:93-99
12. Chagnon YC, Perusse L, Bouchard C 1998 The human obesity gene map: the 1997 update. Obes Res 6:76-92
13. Kirschner LA, Mariash CN 1999 Adipose S14 mRNA is abnormally regulated in obese subjects. Thyroid 9:143-148
14. Nordeen SK 1988 Luciferase reporter gene vectors for analysis of promoters and enhancers. Biotechniques 6:454-458
15. Mariash CN, Seelig S, Schwartz HL, Oppenheimer JH 1986 Rapid synergistic interaction between thyroid hormone and carbohydrate on mRNAS14 induction. J Biol Chem 261:9583-9586
16. Naar AM, Boutin JM, Lipkin SM, Yu VC, Holloway JM, Glass CK, Rosenfeld MG 1991 The orientation and spacing of core DNA-binding motifs dictate selective transcriprional responses to three nuclear receptors. Cell 65:1267-1279
17. Anderson GW, Mariash CN, Oppenheimer JH 2000 molecular actions of thyroid hormone. In: Braverman LE, Utiger RD, eds. The thyroid: a fundamental and clinical text. 8th ed. New York: Lippincott, Williams, and Wilkins; 174-195
18. Sudo Y, Goto Y, Mariash CN 1993 Location of a glucose-dependent response region in the rat S14 promoter. Endocrinology 133:1221-1229
19. Shih HM, Liu Z, Towle HC 1995 Two CACGTG motifs with proper spacing dictate the carbohydrate regulation of hepatic gene transcription. J Biol Chem 270:21991-21997
20. Zhu Q, Mariash A, Margosian MR, Gopinath S, Fareed MT, Anderson GW, Mariash CN 2001 Spot 14 gene deletion increases hepatic de nova lipogenesis. Endocrinology 142:4363-4370
21. Towle HC, Kaytor EN, Shih HM 1997 Regulation of the expression of lipogenic enzyme genes by carbohydrate. Annu Rev Nutr 17:405-433
22. Maia AL, Harney JW, Larsen PR 1996 Is there a negative TRE in the luciferase reporter cDNA? Thyroid 6:325-328
23. Tomasi TE 1991 Utilization rates of thyroid hormones in mammals. Comp Biochem Physiol A Comp Physiol 100:503-516
24. McIver B, Gorman CA 1997 Euthyroid sick syndrome: an overview. Thyroid 7:125-132
25. Anderson GW, Larson RJ, Oas DR, Sandhofer CR, Schwartz HL, Mariash CN, Oppenheimer JH 1998 Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) modulates expression of the Purkinje cell protein-2 gene. A potential role for COUP-TF in repressing premature thyroid hormone action in the developing brain. J Biol Chem 273:16391-16399