Effects of nicotine on dopaminergic neurotransmission

Nicotinic Receptors in the Nervous System

Volumn , Issue , 2001, Pages 51-80

  Rowell, Peter P ^a  

^a UNIVERSITY OF LOUISVILLE HOSPITAL   (United States)

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EID: 0345145157     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (205)

1. Adir J., Miller R.P., and Rotenberg K.S. (1976), Disposition of nicotine in the rat after intravenous administration, Res. Commun. Chem. Pathol. Pharmacol., 13:173-183.
2. Aoshima, H. (1984) A second, slower inactivation process in acetylcholine receptor-rich membrane vesicles prepared from Electrophorus electricus, Arch. Biochem. Biophys., 235:312-318.
3. Arqueros L., Naquira D., and Zunino E. (1978), Nicotine-induced release of catecholamines from rat hippocampus and striatum, Biochem. Pharmacol., 27:2667-2674.
4. Arroyo-Jimnez, M.M., Bourgeois, J.P., Marubio, L.M., Le Sourd, A.M., Ottersen, O.P., Rinvik, E., Fairen, A., and Changeux, J.P. (1999), Ultrastructural localization of the α4-subunit of the neuronal acetylcholine nicotinic receptor in the rat substantia nigra, J. Neurosci., 19:6475-6487.
5. 3H]dopamine in nucleus accumbens slices and its relationship with neocortical afferences, Prog. Neuropsychopharmacol. Biol. Psych., 15:663-676.
6. Balfour, D.J. (1994). Neural mechanisms underlying nicotine dependence, Addiction, 89:1419-1423
7. Balfour, D.J., Birrell, C.E., Moran, R.J., and Benwell, M.E. (1996), Effects of acute D-CPPene on mesoaccumbens dopamine responses to nicotine in the rat, Eur. J. Pharmacol., 316:153-156.
8. Balfour, D.J., Benwell, M.E., Birrell, C.E., Kelly, R.J., and Al-Aloul M. (1998), Sensitization of the mesoaccumbens dopamine response to nicotine, Pharmacol. Biochem. Behav., 59:1021-1030.
9. Barbeau, A., Sourkes, T.L., and Murphy, G.F. (1962), Les catecolamines dans la maladie de Parkinson, in Monoamines et Systeme Nerveux Centrale, Ajuriaguerra, J., Ed. Georg, Geneva, 247-262.
10. Baron, J.A. (1986), Cigarette smoking and Parkinson’s disease, Neurology, 36:1490-1496.
11. Beninato, M. and Spencer, R.F. (1987), A cholinergic projection to the rat substantia nigra from the pedunculopontine tegmental nucleus, Brain Res., 412:169-174.
12. Benowitz, N.L., Zevin, S., and Jacob, P., III. (1997), Sources of variability in nicotine and cotinine levels with use of nicotine nasal spray, transdermal nicotine, and cigarette smoking, Br. J. Clin. Pharmacol., 43:259-267.
13. Benowitz, N.L. (1990), Pharmacokinetic considerations in understanding nicotine dependence, in The Biology of Nicotine Dependence, Bock, G. and Marsh, J., Eds., John Wiley & Sons, New York, Ciba Found. Symp., 152, 186-200.
14. Benowitz, N.L., Porchet, H., and Jacob, P. (1990), Pharmacokinetics, metabolism and pharmacodynamics of nicotine, in Nicotine Psychopharmacology: Molecular, Cellular and Behavioral Aspects, Wonnacott, S., Russell, M.A.H., and Stolerman, I.P., Eds., Oxford University Press, New York, 112-157.
15. Benwell, M.E. and Balfour, D.J. (1992), The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity, Br. J. Pharmacol., 105:849-856, 1992.
16. 3H]nicotine binding sites in human brain, J. Neurochem., 50:1243-1247.
17. Benwell, M.E., Balfour, D.J., and Lucchi, H.M. (1993), Influence of tetrodotoxin and calcium on changes in extracellular dopamine levels evoked by systemic nicotine, Psychopharmacology, 112:467-474.
18. Benwell, M.E., Balfour, D.J., and Birrell, C.E. (1995), Desensitization of the nicotine-induced mesolimbic dopamine responses during constant infusion with nicotine, Br. J. Pharmacol., 114:454-460.
19. Bertler, A. and Rosengren, E. (1959), Occurrence and distribution of dopamine in brain and other tissue, Experiment, 15:10.
20. Birkmayer, W. and Hornykiewicz, O. (1961), Der L-3,4-dioxyphenylalanin (DOPA), Effekt bei der Parkinson-akinese, Wien. Klin. Wschr., 73:787-788.
21. Blaha, C.D. and Winn, P. (1993), Modulation of dopamine efflux in the striatum following cholinergic stimulation of the substantia nigra in intact and pedunculopontine tegmental nucleus-lesioned rats, J. Neurosci., 13:1035-1044.
22. Blaha, C.D., Allen, L.F., Das, S., Inglis, W.L., Latimer, M.P., Vincent, S.R., and Winn, P. (1996), Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and laterodorsal tegmental nucleus-lesioned rats, J. Neurosci., 16:714-722.
23. Bozarth, M.A. and Wise, R.A. (1986), Involvement of the ventral tegmental dopamine system in opioid and psychomotor stimulant reinforcement, in Problems of Drug Dependence, Harris, L.S., Ed., U.S.G.P.O., Washington, DC, 190-196.
24. 3H]nicotine binding in human post-mortem brain, J. Pharmacol. Exp. Ther., 282:7-13.
25. Bridges, R.B., Combs, J.G., Humble, J.W., Turbek, J.A., Rehm, S.R., and Haley, N.J. (1990), Population characteristics and cigarette yield as determinants of smoke exposure, Pharmacol. Biochem. Behav., 37:17-28.
26. Burn, J.H. (1960), The action of nicotine on the peripheral circulation, Ann. N.Y. Acad. Sci., 90:81-84.
27. Cadoni, C. and Di Chiara, G. (2000), Differential changes in accumbens shell and core dopamine in behavioral sensitization to nicotine, Eur. J. Pharmacol., 387:R23-25.
28. Carlsson, A., Lindqvist, M., Magnusson, T., and Waldeck, B. (1958), On the presence of 3-hydroxytyramine in brain, Science, 127:471.
29. Carlsson, A. (1959), The occurrence, distribution and physiological role of catecholamines in the nervous system, Pharmacol. Rev., 11:490-493.
30. Carr, L.A. and Basham, J.K. (1991), Effects of tobacco smoke constituents on MPTP-induced toxicity and monoamine oxidase activity in the mouse brain, Life Sci., 48:1173-1177.
31. Carr, L.A. and Rowell., P.P. (1990), Attenuation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity by tobacco smoke, Neuropharmacology, 29:311-314.
32. Carr, L.A., Rowell, P.P., and Pierce, W.M. Jr. (1989), Effects of subchronic nicotine administration on central dopaminergic mechanisms in the rat, Neurochem. Res., 14:511-515.
33. Carr, L.A., Basham, J.K., and Rowell, P.P. (1991), Inhibition of dopamine uptake in striatal synaptosomes by tobacco smoke fractions, Int. Symp. Dopamine, 1:99-101.
34. +) and dopamine in striatal synaptosomes by tobacco smoke components, Eur. J. Pharmacol., 215:285-287.
35. Celada, P., Paladini, C.A., and Tepper, J.M. (1999), GABAergic control of rat substantia nigra dopaminergic neurons: role of globus pallidus and substantia nigra pars reticulata, Neuroscience, 89:813-825.
36. Chergui, K., Charlety, P.J., Akaoka, H., Saunier, C.F., Brunet, J.L., Buda, M., and Svensson, T.H., and Chovet G. (1993), Tonic activation of NMDA receptors causes spontaneous burst discharge of rat midbrain dopamine neurons in vivo, Eur. J. Neurosci., 5:137-144.
37. Chiou, C.Y., Long, J.P., Potrepka, R., and Spratt, J.L. (1970), The ability of various nicotinic agents to release acetylcholine from synaptic vesicles, Arch. Int. Pharmacodyn. Ther., 187:88-96.
38. Christoffersen, C.L. and Meltzer, L.T. (1995), Evidence for N-methyl-D-aspartate and AMPA subtypes of the glutamate receptor on substantia nigra dopamine neurons: possible preferential role for N-methyl-D-aspartate receptors, Neuroscience, 67:373-381.
39. Clark, D. and Chiodo, L.A. (1988), Electrophysiological and pharmacological characterization of identified nigrostriatal and mesoaccumbens dopamine neurons in the rat, Synapse, 2:474-485.
40. Clarke, P.B., Hommer, D.W., Pert, A., and Skirboll, L.R. (1987), Innervation of substantia nigra neurons by cholinergic afferents from pedunculopontine nucleus in the rat: neuroanatomical and electrophysiological evidence, Neuroscience, 23:1011-1019.
41. Clarke, P.B., Fu, D.S., Jakubovic, A., and Fibiger, H.C. (1988), Evidence that mesolimbic dopaminergic activation underlies the locomotor stimulant action of nicotine in rats, J. Pharmacol. Exp. Ther., 246:701-708.
42. Clarke, P.B. and Pert, A. (1985), Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons, Brain Res., 348:355-358.
43. 125I]α-bungarotoxin, J. Neurosci., 5:1307-1315.
44. Connelly, M.S. and Littleton, J.M. (1983), Lack of stereoselectivity in ability of nicotine to release dopamine from rat synaptosomal preparations, J Neurochem., 41:1297-1302.
45. Corrigall, W.A., Coen, K.M., and Adamson, K.L. (1994), Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area, Brain Res., 653:278-284.
46. Court, J.A., Lloyd, S., Thomas, N., Piggott, M.A., Marshall, E.F., Morris, C.M., Lamb, H., Perry, R.H., Johnson, M., and Perry, E.K. (1998), Dopamine and nicotinic receptor binding and the levels of dopamine and homovanillic acid in human brain related to tobacco use, Neuroscience, 87:63-78.
47. Creese, I. and Sibley, D.R. (1980), Receptor adaptation to centrally acting drugs, Ann. Rev. Pharmacol. Toxicol., 21:357-391.
48. Crooks, P.A. and Dwoskin, L.P. (1997), Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking, Biochem. Pharmacol., 54:743-753.
49. Damsma, G., Day, J., and Fibiger, H.C. (1989), Lack of tolerance to nicotine-induced dopamine release in the nucleus accumbens, Eur. J. Pharmacol., 168:363-368.
50. Dani, J.A., Radcliffe, K.A., and Pidoplichko, V.I. (2000), Variations in desensitization of nicotinic acetylcholine receptors from hippocampus and midbrain dopamine areas, Eur. J. Pharmacol., 393:31-38.
51. Desce, J.M., Godeheu, G., Galli, T., Artaud, F., Cheramy, A., and Glowinski, J. (1991), Presynaptic facilitation of dopamine release through D, L-α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptors on synaptosomes from the rat striatum, J. Pharmacol. Exp. Ther., 259:692-698.
52. deWit, H. and Wise, R.A. (1977), Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide but not with the noradrenergic blockers phentolamine or phenoxybenzamine, Can. J. Psychol., 31:195-203.
53. 3H]dopamine uptake into rat striatal slices by quaternary N-methylated nicotine metabolites, Life Sci., 50:233-237.
54. Dwoskin, L.P., Buxton, S.T., Jewell, A.L., and Crooks, P.A. (1993), S(-)nornicotine increases dopamine release in a calcium-dependent manner from superfused rat striatal slices, J. Neurochem., 60:2167-2174.
55. 3H]dopamine from superfused rat striatal slices, Eur. J. Pharmacol., 276:195-199.
56. 3H]dopamine release from rat striatal slices in a calcium-dependent manner, J. Pharmacol. Exp. Ther., 288:905-911.
57. Egan, T.M. and North, R.A. (1986), Actions of acetylcholine and nicotine on rat locus coeruleus neurons in vitro, Neuroscience, 19:565-571.
58. Ehringer, H. and Hornykiewicz, O. (1960), Verteilung von noradrenalin und dopamin (3-hydroxytyramin) im gehirn des menschen und ihr verhalten bei erkrankungen des extrapyramidalen systems, Klin Wchnschr, 38: 1236-1239.
59. Engberg, G., Kling-Petersen, T., and Nissbrandt, H. (1993), GABAB-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra, Synapse, 15:229-238.
60. Erhardt, S., Andersson, B., Nissbrandt, H., and Engberg, G. (1998), Inhibition of firing rate and changes in the firing pattern of nigral dopamine neurons by gamma-hydroxybutyric acid (GHBA) are specifically induced by activation of GABA(B) receptors, Naunyn Schmiedeberg’s Arch Pharmacol., 357:611-619.
61. Fisher, J.L., Pidoplichko, V.I., and Dani, J.A. (1998), Nicotine modifies the activity of ventral tegmental area dopaminergic neurons and hippocampal GABAergic neurons, J. Physiol. Paris, 92:209-213.
62. Fowler, J.S., Volkow, N.D., Wang, G.J., Pappas, N., Logan, J., MacGregor, R., Alexoff, D., Shea, C., Schlyer, D., Wolf, A.P., Warner, D., Zezulkova, I., and Cilento, R. (1996a), Inhibition of monoamine oxidase B in the brains of smokers, Nature, 379:733-736.
63. Fowler, J.S., Volkow, N.D., Wang, G.J., Pappas, N., Logan, J., Shea, C., Alexoff, D., MacGregor, R.R., Schlyer, D.J., Zezulkova, I., and Wolf, A.P. (1996b), Brain monoamine oxidase A inhibition in cigarette smokers, Proc. Natl. Acad. Sci. U.S.A., 93:14065-14069.
64. Fowler, J.S., Volkow, N.D., Wang, G.J., Pappas, N., Logan, J., MacGregor, R., Alexoff, D., Wolf, A.P., Warner, D., Cilento, R., and Zezulkova, I. (1998), Neuropharmacological actions of cigarette smoke: brain monoamine oxidase B (MAO B) inhibition, J. Addict. Dis., 17:23-34.
65. Fu, Y., Matta, S.G., Valentine, J.D., and Sharp, B.M. (1998), Desensitization and resensitization of norepinephrine release in the rat hippocampus with repeated nicotine administration, Neurosci. Lett., 241:147-150.
66. Fu, Y., Matta, S.G., and Sharp, B.M. (1999), Local α-bungarotoxin sensitive nicotinic receptors modulate nicotine-induced dopamine release in the nucleus accumbens, Soc. Neurosci. Abst., 25:187.
67. 3H]tyrosine in rat nucleus accumbens, J. Pharm. Pharmacol., 41:66-68.
68. Fung, Y.K. and Lau, Y.S. (1992), Chronic effects of nicotine on mesolimbic dopaminergic system in rats, Pharmacol. Biochem. Behav., 41:57-63.
69. Fung, Y.K., Schmid, M.J., Anderson, T.M., and Lau, Y.S. (1996), Effects of nicotine withdrawal on central dopaminergic systems, Pharmacol. Biochem. Behav., 53:635-640.
70. George, T.P., Verrico, C.D., and Roth, R.H. (1998), Effects of repeated nicotine pre-treatment on mesoprefrontal dopaminergic and behavioral responses to acute footshock stress, Brain Res., 801:36-49.
71. Giorguieff, M.F., Le Floc’h, M.L., Glowinski, J., and Besson, M.J. (1977), Involvement of cholinergic presynaptic receptors of nicotinic and muscarinic types in the control of the spontaneous release of dopamine from striatal dopaminergic terminals in the rat, J. Pharmacol. Exp. Ther., 200:535-544.
72. Goldner, F.M., Dineley, K.T., and Patrick, J.W. (1997), Immunohistochemical localization of the nicotinic acetylcholine receptor subunit α6 to dopaminergic neurons in the substantia nigra and ventral tegmental area, Neuroreport, 8:2739-2742.
73. Gonon, F. and Sundstrom, L. (1996), Excitatory effects of dopamine released by impulse flow in the rat nucleus accumbens in vivo, Neuroscience, 75:13-18.
74. Goodman, F.R. (1974), Effects of nicotine on distribution and release of 14C-norepinephrine and 14C-dopamine in rat brain striatum and hypothalamus slices, Neuropharmacology, 13:1025-1032.
75. Grace, A.A. and Bunney, B.S. (1983), Intracellular and extracellular electrophysiology of nigral dopaminergic neurons--3. Evidence for electrotonic coupling, Neuroscience, 10:333-48.
76. Grace, A.A. and Bunney, B.S. (1984), The control of firing pattern in nigral dopamine neurons: burst firing, J. Neurosci., 4:2877-2890.
77. 3H]dopamine release from synaptosomes prepared from mouse striatum, J. Neurochem., 59: 848-856.
78. 3H]dopamine release from mouse striatal synaptosomes, J. Neurochem., 62:1390-1398, 1994.
79. 3H]dopamine release from mouse striatal synaptosomes and response to chronic L-nicotine treatment, J. Pharmacol. Exp. Ther., 282:32-43.
80. Grenhoff, J., Aston-Jones, G., and Svensson, T.H. (1986), Nicotinic effects on the firing pattern of midbrain dopamine neurons, Acta Physiol. Scand., 128:351-358.
81. Grenhoff, J., Ugedo, L., and Svensson, T.H. (1988), Firing patterns of midbrain dopamine neurons: differences between A9 and A10 cells, Acta Physiol. Scand., 134:127-132.
82. 2+ and cAMP in nicotine-elicited elevation of tyrosine hydroxylase mRNA, Am. J. Physiol., 276:C54-65.
83. Haines, C.F. Jr., Mahajan, D.K., Miljkovc, D., Miljkovic, M., and Vesell, E.S. (1974), Radioimmunoassay of plasma nicotine in habituated and naive smokers, Clin. Pharmacol. Ther., 16:1083-1089.
84. Hakan, R.L. and Ksir, C. (1991), Acute tolerance to the locomotor stimulant effects of nicotine in the rat, Psychopharmacology, (Berl) 104:386-390.
85. Harsing, L.G., Jr, Sershen, H., and Lajtha, A. (1992), Dopamine efflux from striatum after chronic nicotine: evidence for autoreceptor desensitization, J. Neurochem., 59:48-54.
86. Hefti, F. and Lichtensteiger, W. (1978), Dendritic dopamine: studies on the release of endogenous dopamine from subcellular particles derived from dendrites of rat nigro-striatal neurons, Neurosci. Lett, 10:65-70.
87. Henningfield, J.E., Stapleton, J.M., Benowitz, N.L., Grayson, R.F., and London, E.D. (1993), Higher levels of nicotine in arterial than in venous blood after cigarette smoking, Drug Alcohol Depend., 33:23-29.
88. Holtz, P, Credner, K., and Koepp, W. (1942), Die enzymatische entstehung von Oxytyramin im organismus und die ohysiologische bedeutung der dopadecarboxylase, Naunyn Schmiedeberg’s Arch. Exp. Path. Pharmak., 200:356-388.
89. 3H]dopamine release in rat striatum, J. Neurochem., 56:603-610.
90. Janson, A.M., Hedlund, P.B., Hillefors, M., and von Euler, G. (1992), Chronic nicotine treatment decreases dopamine D2 agonist binding in the rat basal ganglia, Neuroreport, 3:1117-1120.
91. 3H]dopamine release in rat striatal slices via glutamate release, Mol. Pharmacol., (in press).
92. 3H]dopamine release from rat striatal synaptosomes and slices, J. Neurochem., 70:1069-1076.
93. Khalil, A.A., Steyn, S., Castagnoli, N. Jr. (2000), Isolation and characterization of a monoamine oxidase inhibitor from tobacco leaves, Chem. Res. Toxicol., 13:31-35.
94. Kirch, D.G., Taylor, T.R., Creese, I., Xu, S.X., and Wyatt, R.J. (1992), Effect of chronic nicotine treatment and withdrawal on rat striatal D1 and D2 dopamine receptors, J. Pharm. Pharmacol., 44:89-92.
95. Kretschmer, B.D. (1999), Modulation of the mesolimbic dopamine system by glutamate: role of NMDA receptors, J. Neurochem., 73:839-848.
96. Kulak, J.M., Nguyen, T.A., Olivera, B.M, and McIntosh, J.M. (1997), Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes, J. Neurosci., 17:5263-5270.
97. Kyerematen, G.A., Damiano, M.D., Dvorchik, B.H, and Vesell, E.S. (1982), Smoking-induced changes in nicotine disposition: application of a new HPLC assay for nicotine and its metabolites, Clin. Pharmacol. Ther., 32:769-780.
98. Kyerematen, G.A., Taylor, L.H., deBethizy, J.D., and Vesell, E.S. (1988), Pharmacokinetics of nicotine and 12 metabolites in the rat. Application of a new radiometric high performance liquid chromatography assay, Drug Metab. Dispos., 16:125-129.
99. Kyerematen, G.A., Morgan, M.L., Chattopadhyay, B., deBethizy, J.D., and Vesell, E.S. (1990), Disposition of nicotine and eight metabolites in smokers and nonsmokers: identification in smokers of two metabolites that are longer lived than cotinine, Clin. Pharmacol. Ther., 48:641-651.
100. Lanca, A.J., Adamson, K.L., Coen, K.M., Chow, B.L., and Corrigall, W.A. (2000), The pedunculopontine tegmental nucleus and the role of cholinergic neurons in nicotine self-administration in the rat: a correlative neuroanatomical and behavioral study, Neuroscience, 96:735-742.
101. Lapin, E.P., Maker, H.S., Sershen, H., and Lajtha, A. (1989), Action of nicotine on accumbens dopamine and attenuation with repeated administration, Eur. J. Pharmacol., 160:53-59.
102. Le Novère, N., Zoli, M., and Changeux, J.P. (1996), Neuronal nicotinic receptor α6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain, Eur. J. Neurosci., 8:2428-2439.
103. Levin, E.D., Torry, D., Christopher, N.C., Yu X., Einstein, G., and Schwartz-Bloom, R.D. (1997), Is binding to nicotinic acetylcholine and dopamine receptors related to working memory in rats? Brain Res. Bull., 43:295-304.
104. Lichtensteiger, W., Felix, D., Lienhart, R., and Hefti, F. (1976), A quantitative correlation between single unit activity and fluorescence intensity of dopamine neurones in zona compacta of substantia nigra, as demonstrated under the influence of nicotine and physostigmine, Brain Res., 117:85-103.
105. Lichtensteiger, W., Hefti, F., Felix, D., Huwyler, T., Melamed, E., and Schlumpf, M. (1982), Stimulation of nigrostriatal dopamine neurones by nicotine, Neuropharmacology, 21:963-968.
106. Lippiello, P.M., Bencherif, M., Prince, R.J. (1995), The role of desensitization in CNS nicotinic receptor function, in Effects of Nicotine in Biological Systems II, Clarke, P.B.S., Quik, M., Adlkofer, F., and Thurau, K., Eds., Birkhauser Verlag, Basel, 79-85.
107. Lukas, R.J. (1991), Effects of chronic nicotinic ligand exposure on functional activity of nicotinic acetylcholine receptors expressed by cells of the PC12 rat pheochromocytoma or the TE671/RD human clonal line, J. Neurochem., 56:1134-1145.
108. Lyness, W.H., Friedle, N.M., and Moore, K.E. (1979), Destruction of dopaminergic nerve terminals in nucleus accumbens: effect on d-amphetamine self-administration, Pharmacol. Biochem. Behav., 11:553-556.
109. 3H]dopamine release from dendrosomes of rat substantia nigra, Naunyn Schmiedeberg’s Arch. of Pharmacol., 344:275-280.
110. Marks, M.J., Burch, J.B., and Collins, A.C. (1983), Effects of chronic nicotine infusion on tolerance development and nicotinic receptors, J. Pharmacol. Exp Ther., 226:817-825.
111. Marks, M.J., Farnham, D.A., Grady, S.R., and Collins, A.C. (1993a), Nicotinic receptor function determined by stimulation of rubidium efflux from mouse brain synaptosomes, J. Pharmacol. Exp. Ther., 264:542-552.
112. Marks, M.J., Grady, S.R., and Collins, A.C. (1993b), Downregulation of nicotinic receptor function after chronic nicotine infusion, J. Pharmacol. Exp. Ther., 266:1268-1276.
113. + efflux from mouse brain synaptosomes, J. Neurochem., 63:2125-2135.
114. Marshall, D., Soliakov, L., Redfern, P., and Wonnacott, S. (1996), Tetrodotoxin-sensitivity of nicotine-evoked dopamine release from rat striatum, Neuropharmacology, 35:1531-1536.
115. Marshall, D.L., Redfern, P.H., and Wonnacott, S. (1997), Presynaptic nicotinic modulation of dopamine release in the three ascending pathways studied by in vivo microdialysis: comparison of naïve and chronic nicotine-treated rats, J. Neurochem., 68:1511-1519.
116. Meltzer, L.T., Christoffersen, C.L., and Serpa, K.A. (1997), Modulation of dopamine neuronal activity by glutamate receptor subtypes, Neurosci. Biobehav. Rev., 21:511-518.
117. Mendez-Alvarez, E., Soto-Otero, R., Sanchez-Sellero, I., and Lopez-Rivadulla Lamas, M. (1997), Inhibition of brain monoamine oxidase by adducts of 1,2,3,4-tetrahydroisoquinoline with components of cigarette smoke, Life Sci., 60:1719-1727.
118. Mifsud, J.C., Hernandez, L., and Hoebel, B.G. (1989), Nicotine infused into the nucleus accumbens increases synaptic dopamineas measured by in vivo microdialysis, Brain Res., 478:365-367.
119. Miller, R.P., Rotenberg, K.S., and Adir, J. (1977), Effect of dose on the pharmacokinetics of intravenous nicotine in the rat, Drug Metab. Dispos., 5:436-443.
120. Miyata, H., Ando, K., and Yanagita, T. (1996), Comparison of the effects of nicotine and methamphetamine on extracellular dopamine in the nucleus accumbens of behaviorally sensitized rats, Nihon Shinkei Seishin Yakurigaku Zasshi, 16:41-47.
121. Morens, D.M., Grandinetti, A., Reed, D., White, L.R., and Ross, G.W. (1995), Cigarette smoking and protection from Parkinson’s disease: false association or etiologic clue? Neurology, 45:1041-1051.
122. Morley, B.J., Kemp, G.E., and Salvaterra, P. (1979), α-bungarotoxin binding sites in the CNS, Life Sci., 24:859-872.
123. Naquira, D., Zunino, E., Arqueros, L., and Viveros, O.H. (1978), Chronic effects of nicotine on catecholamine synthesizing enzymes in rats, Eur. J. Pharmacol., 47:227-229.
124. Nefzger, M.D., Quadfasel, F.A., and Karl, V.C. (1968), A retrospective study of smoking in Parkinson’s disease, Am. J. Epidemiol., 88:149-158.
125. Nirenberg, M.J., Vaughan, R.A., Uhl, G.R., Kuhar, M.J., and Pickel, V.M. (1996), The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons, J. Neurosci., 16:436-447.
126. Nisell, M., Nomikos, G.G., and Svensson, T.H. (1994a), Infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release, Pharmacol. Toxicol., 75:348-352.
127. Nisell, M., Nomikos, G.G., and Svensson, T.H. (1994b), Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area, Synapse, 16:36-44.
128. Nisell, M., Nomikos, G.G., Hertel, P., Panagis, G., and Svensson, T.H. (1996), Conditionindependent sensitization of locomotor stimulation and mesocortical dopamine release following chronic nicotine treatment in the rat, Synapse, 22:369-381.
129. Nisell, M., Marcus, M., Nomikos, G.G., and Svensson, T.H. (1997), Differential effects of acute and chronic nicotine on dopamine output in the core and shell of the rat nucleus accumbens, J. Neural Transm., 104:1-10.
130. Ochoa, E.L., Li, L., and McNamee, M.G. (1990), Desensitization of central cholinergic mechanisms and neuroadaptation to nicotine, Mol. Neurobiol., 4:251-287.
131. Olds, J. and Milner, P. (1954), Positive reinforcement produced by electrical stimulation of septal areas and other regions of rat brain, J. Comp. Physiol. Psychol., 47:419-427.
132. Olds, J. and Olds, M.E. (1963), Approach-avoidance analysis of rat diencephalon, J. Comp. Neurol., 120: 259-295.
133. Oreland, L., Fowler, C.J., and Schalling, D. (1981), Low platelet monoamine oxidase activity in cigarette smokers, Life Sci., 29:2511-2518.
134. Oswald, R.E. and Freeman, J.A. (1981), Alpha-bungarotoxin binding and central nervous system nicotinic acetylcholine receptors, Neuroscience, 6:1-14.
135. Overton, P. and Clark, D. (1991), N-methyl-D-aspartate increases the excitability of nigrostriatal dopamine terminals, Eur. J. Pharmacol., 201:117-120.
136. Overton, P. and Clark, D. (1992), Electrophysiological evidence that intrastriatally administered N-methyl-D-aspartate augments striatal dopamine tone in the rat, J. Neural Transm. Park Dis. Dement., 4:1-14.
137. Overton, P.G. and Clark, D. (1997), Burst firing in midbrain dopaminergic neurons, Brain Res. Brain Res. Rev., 25:312-334.
138. Paladini, C.A., Iribe, Y., and Tepper, J.M. (1999), GABA-A receptor stimulation blocks NMDA-induced bursting of dopaminergic neurons in vitro by decreasing input resistance, Brain Res., 832:145-151.
139. Pawlak, R., Takada, Y., Takahashi, H., Urano, T., Ihara, H., Nagai, N., and Takada, A. (2000), Differential effects of nicotine against stress-induced changes in dopaminergic system in rat striatum and hippocampus, Eur. J. Pharmacol., 387:171-177.
140. Pidoplichko, V.I., DeBiasi, M., Williams, J.T., and Dani, J.A. (1997), Nicotine activates and desensitizes midbrain dopamine neurons, Nature, 390:401-404.
141. Plowchalk, D.R., Andersen, M.E., and deBethizy, J.D. (1992), A physiologically based pharmacokinetic model for nicotine disposition in the Sprague-Dawley rat, Toxicol. Appl. Pharmacol., 116:177-188, 1992.
142. 3H]dopamine release from rat striatal synaptosomes by voltage-sensitive calcium channel ligands, Biochem. Pharmacol., 52:613-618
143. Rapier, C., Lunt, G.G., and Wonnacott, S. (1988), Stereoselective nicotine-induced release of dopamine from striatal synaptosomes: concentration dependence and repetitive stimulation, J. Neurochem., 50:1123-1130.
144. Reid, M.S., Ho, L.B., and Berger, S.P. (1998), Behavioral and neurochemical components of nicotine sensitization following 15-day pretreatment: studies on contextual conditioning, Behav. Pharmacol., 9:137-148.
145. 3H]domperidone in rat nucleus accumbens, J. Neurosci. Res., 18:621-625.
146. Reuben, M., Boye, S., and Clarke, P.B. (2000), Nicotinic receptors modulating somatodendritic and terminal dopamine release differ pharmacologically, Eur. J. Pharmacol., 393:39-49.
147. Risner, M. and Jones, B.E. (1976), Role of noradrenergic and dopaminergic processes in amphetamine self-administration, Pharmacol. Biochem. Behav., 5:477-482
148. Risner, M.E. and Jones, B.E. (1980), Intravenous self-administration of cocaine and norcaine by dose, Psychopharmacology, 71:83-89.
149. Roberts, D.C.S. and Koob, G.F. (1982), Disruption of cocaine self-adminstration following 6-hydroxydopamine lesions of the ventral tegmental area in rats, Pharmacol. Biochem. Behav., 17:901-904.
150. Robertson, A. and Mogenson, G.J. (1978), Evidence for a role for dopamine in self-stimulation of the nucleus accumbens of the rat, Can. J. Psychol., 32:67-76.
151. Rosenberg, J., Benowitz, N.L., Jacob, P., and Wilson, K.M. (1980), Disposition kinetics and effects of intravenous nicotine, Clin. Pharmacol. Ther., 28:517-522.
152. Rowell, P.P. (1987), Current concepts on the effects of nicotine on neurotransmitter release in the central nervous system, Adv. Behav. Biol., 31:191-208.
153. 3H]dopamine from rat striatal synaptosomes, Neurosci. Lett., 189:171-175.
154. 3H]dopamine release by nicotine in rat nucleus accumbens, J. Neurochem., 49:1449-1454.
155. Rowell, P.P. and Wonnacott, S. (1990), Evidence for functional activity of upregulated nicotine binding sites in rat striatal synaptosomes, J. Neurochem., 55, 2105-2110.
156. Rowell, P.P. and Hill, A.S. (1993), Apparent inability of nicotine to inhibit dopamine uptake into rat striatal tissue in vitro, Pharmacologist, 35:134.
157. Rowell, P.P. and Hillebrand, J.A. (1994), Desensitization of nicotine-stimulated dopamine release from rat striatal synaptosomes, J. Neurochem., 63:561-569.
158. Rowell, P.P. and Li, M. (1997), Dose-response relationship for nicotine-induced up-regulation of rat brain nicotinic receptors, J. Neurochem., 68:1982-1989.
159. Rowell, P.P. and Duggan, D.S. (1998), Long-lasting inactivation of nicotinic receptor function in vitro by treatment with high concentrations of nicotine, Neuropharmacology, 37:103-111.
160. Russell, M.A.H. (1990), Nicotine intake and its control over smoking, in Nicotine Psychopharmacology: Molecular, Cellular and Behavioral Aspects, Wonnacott, S., Russell, M.A.H. and Stolerman, I.P., Eds., Oxford University Press, New York, 374-418.
161. Russell, M.A. and Feyerabend, C. (1978), Cigarette smoking: a dependence on high-nicotine boli, Drug Metab. Rev., 8:29-57.
162. 3H]metabolites in rat striatum by nicotinic drugs, Brain Res., 242:99-106.
163. Sano, I., Gamo, T., Kakimoto, Y., Taniguchi, K. Takesada, M., and Michinuma, K. (1959), Distribution of catechol compounds in human grain, Biochemica Biochysica Acta, 32:586-587.
164. Sastry, B.V., Chance, M.B., Singh, G., Horn, J.L., and Janson, V.E. (1995), Distribution and retention of nicotine and its metabolite, cotinine, in the rat as a function of time, Pharmacology, 50:128-136.
165. Schilström, B., Nomikos, G.G., Nisell, M., Hertel, P., and Svensson, T.H. (1998a), N-methyl-D-aspartate receptor antagonism in the ventral tegmental area diminishes the systemic nicotine-induced dopamine release in the nucleus accumbens, Neuroscience, 82:781-789.
166. Schilström, B., Svensson, H.M., Svensson, T.H., and Nomikos, G.G. (1998b), Nicotine and food induced dopamine release in the nucleus accumbens of the rat: putative role of α7 nicotinic receptors in the ventral tegmental area, Neuroscience, 85:1005-1009.
167. Schwartz, R.D. and Kellar, K.J. (1983), Nicotinic cholinergic receptor binding sites in the brain: regulation in vivo, Science, 220:214-216.
168. 3H]acetylcholine recognition sites in brain by nicotinic cholinergic drugs, J. Neurochem., 45:427-433.
169. Sharp, B.M. and Matta, S.G. (1993), Detection by in vivo microdialysis of nicotine-induced norepinephrine secretion from the hypothalamic paraventricular nucleus of freely moving rats: dose-dependency and desensitization, Endocrinology, 133:11-19.
170. Sharples, C.G., Kaiser, S., Soliakov, L., Marks, M.J., Collins, A.C., Washburn, M., Wright, E., Spencer, J.A., Gallagher, T., Whiteaker, P., and Wonnacott, S. (2000), A novel nicotinic agonist with subtype selectivity implicates the α4β2* subtype in the modulation of dopamine release from rat striatal synaptosomes, J Neurosci, 20:2783-2791.
171. Shiffman, S., Zettler-Segal, M., Kassel, J., Paty, J., Benowitz, N.L., and O’Brien, G. (1992), Nicotine elimination and tolerance in non-dependent cigarette smokers, Psychopharmacology (Berl), 109:449-456.
172. Shoaib, M., Schindler, C.W., Goldberg, S.R., and Pauly, J.R. (1997), Behavioral and biochemical adaptations to nicotine in rats: influence of MK801, an NMDA receptor antagonist, Psychopharmacology (Berl), 134:121-130.
173. Silbergeld, E.K. and Walters, J.R. (1979), Synaptosomal uptake and release of dopamine in substantia nigra: effects of gamma-aminobutyric acid and substance, P. Neurosci. Lett., 12:119-126.
174. Simasko, S.M., Soares, J.R., and Weiland, G.A. (1986), Two components of carbamylcholineinduced loss of nicotinic acetylcholine receptor function in the neuronal cell line PC12, Mol. Pharmacol., 30:6-12.
175. Singer, G., Wallace, M., and Hall, R. (1982), Effects of dopaminergic nucleus accumbens lesions on the acquisition of schedule induced self injection of nicotine in the rat, Pharmacol. Biochem. Behav., 17:579-581.
176. Smith, J.E., Guerin, G.F., Co, C., Barr, T.S., and Lane, J.D. (1985), Effects of 6-OHDA lesions of the central medial nucleus accumbens on rat intravenous morphine self-administration, Pharmacol. Biochem. Behav., 23:843-849.
177. 3H]dopamine release from rat striatal synaptosomes, J. Neurochem., 67:163-170.
178. Sorenson, E.M., Shiroyama, T., and Kitai, S.T. (1998), Postsynaptic nicotinic receptors on dopaminergic neurons in the substantia nigra pars compacta of the rat, Neurosci., 87:659-673.
179. Stein, E.A., Pankiewicz, J., Harsch, H.H., Cho, J.K., Fuller, S.A., Hoffmann, R.G., Hawkins, M., Rao, S.M., Bandettini, P.A., and Bloom, A.S. (1998), Nicotine-induced limbic cortical activation in the human brain: a functional MRI study, Am. J. Psychiatry, 155:1009-1015.
180. Stein, L. (1962), Effects and interactions of imipramine, chlorpromazine, reserpine, and amphetamine on self-stimulation: possible neurophysiological basis of depression, in Recent Advances in Biological Psychiatry, Plenum Press, New York, 288-308.
181. Suaud-Chagny, M.F., Chergui, K., Chouvet, G., and Gonon, F. (1992), Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area, Neuroscience, 49:63-72.
182. Summers, K.L. and Giacobini, E. (1995), Effects of local and repeated systemic administration of (-) nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex, Neurochem. Res., 20:753-759.
183. Svensson, T.H., Mathe, J.M., Nomikos, G.G., and Schilström, B. (1998), Role of excitatory amino acids in the ventral tegmental area for central actions of non-competitive NMDA-receptor antagonists and nicotine, Amino Acids, 14:51-56.
184. Takahashi, H., Takada, Y., Nagai, N., Urano, T., and Takada, A. (1998), Effects of nicotine and footshock stress on dopamine release in the striatum and nucleus accumbens, Brain Res. Bull., 452:157-162.
185. Takaki, T. (1995), Chronic treatment with nicotine enhances the sensitivity of dopamine autoreceptors that modulate dopamine release from the rat striatum, Nihon Shinkei Seishin Yakurigaku Zasshi, 15:335-1344.
186. Taylor, J.R. and Robbins, T.W. (1986), 6-Hydroxydopamine lesions of the nucleus accumbens, but not of the caudate nucleus, attenuate enhanced responding with reward-related stimuli produced by intra-accumbens d-amphetamine, Psychopharmacology, (Berl) 90:390-397.
187. 3H]dopamine uptake, J. Pharmacol. Exp. Ther., 280:1432-1444.
188. 3H]dopamine from rat striatal synaptic vesicles: comparison with d-amphetamine, J. Neurochem., 71:258-265.
189. Toth, E., Sershen, H., Hashim, A., Vizi, E.S., and Lajtha, A. (1992), Effect of nicotine on extracellular levels of neurotransmitters assessed by microdialysis in various brain regions: role of glutamic acid, Neurochem. Res., 17:265-271.
190. Vander Eecken, H.V., Adams, R.D., and Van Bogaert, L. (1960), Striopallidal-nigral degeneration; an hitherto undescribed lesion in paralysis agitans, J. Neuropathol. Exp. Neurol., 19:159-161.
191. Vizi, E.S. and Lendvai, B. (1999), Modulatory role of presynaptic nicotinic receptors in synaptic and non-synaptic chemical communication in the central nervous system, Brain Res. Brain Res. Rev., 30:219-35.
192. Vogt, M. (1959), Proc. 4th Int. Cong. Biochem, Vol. 3, Brucker, F., Ed., Pergamon, London, 279.
193. Westerink, B.H., Kwint, H.F., and deVries, J.B. (1996), The pharmacology of mesolimbic dopamine neurons: a dual-probe microdialysis study in the ventral tegmental area and nucleus accumbens of the rat brain, J. Neurosci., 16:2605-2611.
194. 3H]dopamine from rat brain slices, Neuropharmacology, 13:693-700.
195. Westfall, T.C., Perry H., and Vickery, L. (1987), Mechanisms of nicotine regulation of dopamine release in neostriatum, in Tobacco Smoking and Nicotine, Martin, W.R., Van Loon, G.R., Iwamoto, E.T., and Davis, L., Eds., Plenum Press, New York, 209-223.
196. Whiteaker, P., Garcha, H.S., Wonnacott, S., and Stolerman, I.P. (1995), Locomotor activation and dopamine release produced by nicotine and isoarecolone in rat, Br. J. Pharmacol., 116:2097-105.
197. Wise, R.A. and Bozarth, M.A. (1985), Brain mechanisms of drug reward and euphoria, Psychiatr. Med., 3:445-460.
198. Wonnacott, S. (1990), The paradox of nicotinic acetylcholine receptor upregulation by nicotine, Trends Pharmacol. Sci., 11:216-219.
199. Wonnacott, S., Irons, J., Rapier, C., Thorne, B., and Lunt, G.G. (1989), Presynaptic modulation of transmitter release by nicotinic receptors, Prog. Brain Res., 79:157-163.
200. Wonnacott, S., Kaiser, S., Mogg, A., Soliakov, L., and Jones, I.W. (2000), Presynaptic nicotinic receptors modulating dopamine release in the rat striatum, Eur. J. Pharmacol., 393:51-58.
201. Yin, R. and French, E.D. (2000), A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study, Brain Res. Bull., 51:507-514.
202. Yong, V.W. and Perry, T.L. (1986), Monoamine oxidase B, smoking, and Parkinson’s disease, J. Neurol. Sci., 72:265-272.
203. Yoshida, M., Yokoo, H., Tanaka, T., Mizoguchi, K., Emoto, H., Ishii, H., and Tanaka, M. (1993), Facilitatory modulation of mesolimbic dopamine neuronal activity by a muopioid agonist and nicotine as examined with in vivo microdialysis, Brain Res., 624:277-280.
204. Yu, P.H. and Boulton, A.A. (1987), Irreversible inhibition of monoamine oxidase by some components of cigarette smoke, Life Sci., 41:675-682.
205. Yu, Z.J. and Wecker, L. (1994), Chronic nicotine administration differentially affects neurotransmitter release from rat striatal slices, J. Neurochem., 63:186-194.