Exfoliative Dermatitis Induced by Leflunomide Therapy [2]

Journal of Dermatology

Volumn 30, Issue 11, 2003, Pages 845-846

  Bandyopadhyay, Debabrata ^a,b  

^a R G KAR MEDICAL COLLEGE   (India)

^b NONE   (India)

Author keywords

Erythroderma; Exfoliative dermatitis; Leflunomide; Rheumatoid arthritis

Indexed keywords

COLESTYRAMINE; HYDROXYCHLOROQUINE; HYDROXYZINE; IBUPROFEN; LEFLUNOMIDE; METHOTREXATE; OMEPRAZOLE; PREDNISOLONE; SALAZOSULFAPYRIDINE;

ADULT; ALLERGY; ALOPECIA; BLOOD TOXICITY; CASE REPORT; CLINICAL FEATURE; DRY SKIN; ERYTHEMA MULTIFORME; ERYTHRODERMA; EXFOLIATIVE DERMATITIS; HUMAN; LETTER; LIVER TOXICITY; MALE; PRURITUS; RASH; RHEUMATOID ARTHRITIS; STEVENS JOHNSON SYNDROME; STOMACH DISEASE; TOXIC EPIDERMAL NECROLYSIS;

EID: 0345095495     PISSN: 03852407     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1346-8138.2003.tb00490.x     Document Type: Letter

References (7)

1. Freedberg IM: Exfoliative Dermatitis, in. Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF (eds): Dermatology in General Medicine, McGraw Hill, New York, 1993, pp 527-531.
2. Arava, leflunomide tablets [product monograph], Aventis Pharma Inc. 2001.
3. Smolen JS, Emery P: Efficacy and safety of leflunomide in active rheumatoid arthritis, Rheumatology, 39 (suppl 1): 48-56, 2000.
4. Adverse Drug Reactions Advisory Committee (ADRAC). Leflunomide: Serious hepatic, blood, skin and respiratory reactions. Australian Adverse Drug Reactions Bulletin, 20: 7, 2001. http://www.health.gov.au/tga/adr/aadrb.htm
5. European Agency for the Evaluation of Medicinal Products. EMEA public statement on leflunomide (Arava®): pancytopenia and serious skin reactions [doc ref EMEA/31637/99] (1999) http://www.emea.eu.int/htms/human/drugalert/drugalert.htm
6. Soliotis F, Glover M, Jawad ASM: Severe skin reaction after leflunomide and etanercept in a patient with rheumatoid arthritis, Ann Rheum Dis, 61: 850-851, 2002.
7. Kremer J: Rational use of new and existing disease-modifying agents in rheumatoid arthritis, Ann Intern Med, 134: 695-706, 2001.