Quantitative structure-activity and structure-toxicity relationships of 4-aminodiphenyl sulphone derivatives with antiinflammatory activity

Quantitative Structure-Activity Relationships

Volumn 18, Issue 1, 1999, Pages 43-51

  Seydel, Joachim K ^a   Bürger, Hanna ^a   Saxena, Anil K ^a,b   Coleman, Michael D ^c   Smith, Stephen N ^c   Perris, Alan D ^c  

^a RESEARCH CENTER BORSTEL   (Germany)

^b A V Humboldt Fellow Ctrl Drug R   (India)

^c ASTON UNIVERSITY   (United Kingdom)

Author keywords

2'4' Substituted 4 aminodiphenyl sulphones; Activity; Antiinflammatory; Cell adhesion; Cell burst; Diffusion into erythrocytes; Methaemoglobin formation; PC and multiple regression analysis

Indexed keywords

BLOOD; CELL ADHESION; CELL DEATH; PRINCIPAL COMPONENT ANALYSIS; REGRESSION ANALYSIS;

2'4'-SUBSTITUTED 4-AMINODIPHENYL SULPHONE; ACTIVITY; ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY ACTIVITY; CELL BURST; CELLS ADHESION; DIFFUSION INTO ERYTHROCYTE; METHEMOGLOBIN FORMATION; MULTIPLE REGRESSION ANALYSIS; PRINCIPAL COMPONENT REGRESSION ANALYSIS;

DIFFUSION;

ANTIINFLAMMATORY AGENT; METHEMOGLOBIN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ADHESION; LIPOPHILICITY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

EID: 0345059436     PISSN: 09318771     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-3838(199901)18:1<43::aid-qsar43>3.0.co;2-%23     Document Type: Article

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