Cloning and genomic organization of the TTL gene on mouse chromosome 2 and human chromosome 2q13

Cytogenetic and Genome Research

Volumn 101, Issue 1, 2003, Pages 47-53

  Erck, C ^a   MacLeod, R A F ^b   Wehland, J ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b LEIBNIZ INSTITUTE DSMZ GERMAN COLLECTION OF MICROORGANISMS AND CELL CULTURES   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA; GLUTAMIC ACID; LIGASE; PEPTIDE SYNTHASE; TUBULIN TYROSINE LIGASE; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL; ANIMAL CELL; ARTICLE; CATTLE; CELL STRAIN 3T3; CHEMISTRY; CHROMOSOMAL LOCALIZATION; CHROMOSOME; CHROMOSOME 2; CHROMOSOME 2Q; CHROMOSOME 2Q13; CHROMOSOME ABERRATION; CHROMOSOME MAP; CONTROLLED STUDY; DNA FLANKING REGION; DNA ISOLATION; DNA SEQUENCE; EMBRYO; EXON; FIBROBLAST; FLUORESCENCE IN SITU HYBRIDIZATION; GENE INSERTION; GENE MAPPING; GENE SEQUENCE; GENETIC ORGANIZATION; GENETICS; GENOME; HELA CELL; HUMAN; HUMAN CELL; INTRON; MOLECULAR CLONING; MOLECULAR GENETICS; MOUSE; MOUSE STRAIN; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; STRUCTURAL GENE; SWINE; TUMOR; TUMOR CELL LINE; UTERINE CERVIX CANCER;

5' FLANKING REGION; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 2; CHROMOSOMES, MAMMALIAN; CLONING, MOLECULAR; DNA; DNA, COMPLEMENTARY; EXONS; GENES; HELA CELLS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRONS; MICE; MICE, INBRED STRAINS; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; PEPTIDE SYNTHASES; PHYLOGENY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID;

BOVINAE; INSERTION SEQUENCES; MURINAE; SUIDAE;

EID: 0345017610     PISSN: 14248581     EISSN: None     Source Type: Journal    
DOI: 10.1159/000073418     Document Type: Article

References (23)

1. Alonso AC, Arce CA, Barra HS: Relationship between the tyrosination state of tubulin and the activities of tubulin:tyrosine ligase and tubulin carboxypeptidase in rat muscle during development. Eur J Biochem 177:517-522 (1988).
2. Antich J, Carbonell X, Mas J, Clusellas N: De novo interstitial deletion of the long arm of chromosome 2 in a malformed newborn with a karyotype: 46,XY,del(2)(q12q14). Acta paediatr scand 72: 631-633 (1983).
3. Barra HS, Rodriguez JA, Arce CA, Caputto R: A soluble preparation from rat brain that incorporates into its own proteins (14C)arginine by a ribonuclease-sensitive system and (14C)tyrosine by a ribonuclease-insensitive system. J Neurochem 20:97-108 (1973).
4. Barra HS, Arce CA, Argarana CE: Posttranslational tyrosination/ detyrosination of tubulin. Mol Neurobiol 2:133-153 (1988).
5. Deanin GG, Thompson WC, Gordon MW: Tyrosyltubulin ligase activity in brain, skeletal muscle, and liver of the developing chick. Dev Biol 57:230-233 (1977).
6. Dideberg O, Bertrand J: Tubulin tyrosine ligase: a shared fold with the glutathione synthetase ADP-forming family. Biochem Sci 23:57-58 (1998).
7. Dong JT: Chromosomal deletions and tumor suppressor genes in prostate cancer. Cancer Metastasis Rev 20:173-193 (2001).
8. Erck C, Frank R, Wehland J: Tubulin-tyrosine ligase, a long-lasting enigma. Neurochem Res 25:5-10 (2000).
9. Ersfeld K, Wehland J, Plessmann U, Dodemont H, Gerke V, Weber K: Characterization of the tubulin-tyrosine ligase. J Cell Biol 120:725-732 (1993).
10. Gayther SA, Barski P, Batley SJ, Li L, de Foy KA, Cohen SN, Ponder BA, Caldas C: Aberrant splicing of the TSG101 and FHIT genes occurs frequently in multiple malignancies and in normal tissues and mimics alterations previously described in tumours. Oncogene 15:2119-2126 (1997).
11. Kalisz HM, Erck C, Plessmann U, Wehland J: Incorporation of nitrotyrosine into alpha-tubulin by recombinant mammalian tubulin-tyrosine ligase. Biochim biophys Acta 1481:131-138 (2000).
12. Lafanechere L, Courtay-Cahen C, Kawakami T, Jacrot M, Rudiger M, Wehland J, Job D, Margolis RL: Suppression of tubulin tyrosine ligase during tumor growth. J Cell Sci 111:171-181 (1998).
13. MacLeod RAF, Drexler HG: Cytogenetic characterization of tumor cell lines, in Langdon S (ed): Cancer cell culture-methods and protocols, in press (Humana Press, Totowa 2003).
14. MacRae TH: Tubulin post-translational modifications - enzymes and their mechanisms of action. Eur J Biochem 244:265-278 (1997).
15. Mialhe A, Lafanechere L, Treilleux I, Peloux N, Dumontet C, Bremond A, Panh MH, Payan R, Wehland J, Margolis RL, Job D: Tubulin detyrosination is a frequent occurrence in breast cancers of poor prognosis. Cancer Res 61: 5024-5027 (2001).
16. Preston SF, Deanin GG, Hanson RK, Gordon MW: The phylogenetic distribution of tubulin:tyrosine ligase. J molec Evol 13:233-244 (1979).
17. Raybin D, Flavin M: An enzyme tyrosylating alpha-tubulin and its role in microtubule assembly. Biochem biophys Res Commun 65:1088-1095 (1975).
18. Rodriguez JA, Borisy GG: Modification of the C-terminus of brain tubulin during development. Biochem biophys Res Commun 83:579-586 (1978).
19. Smale ST: Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes. Biochim biophys Acta 1351:73-88 (1997).
20. Sumption ND, Barber JC: A transmitted deletion of 2q13 to 2q14.1 causes no phenotypic abnormalities. J med Genet 38:125-127 (2001).
21. Tate P, Lee M, Tweedie S, Skarnes WC, Bickmore WA: Capturing novel mouse genes encoding chromosomal and other nuclear proteins. J Cell Sci 111:2575-2585 (1998).
22. Trichet V, Ruault M, Roizes G, De Sario A: Characterization of the human tubulin tyrosine ligase-like 1 gene (TTLL1) mapping to 22q13.1. Gene 257: 109-117 (2000).
23. Turpin E, Dalle B, de Roquancourt A, Plassa LF, Marty M, Janin A, Beuzard Y, de The H: Stress-induced aberrant splicing of TSG101: association to high tumor grade and p53 status in breast cancers. Oncogene 18:7834-7837 (1999).