Heterogeneous expression of Galα1-3Gal xenoantigen in pig kidney: A lectin and immunogold electron microscopic study

Transplantation

Volumn 66, Issue 11, 1998, Pages 1495-1503

  Strokan, Valeri ^a   Mölne, Johan ^a   Svalander, Christian T ^a   Breimer, Michael E ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GALACTOSE ALPHA1 3 GALACTOSE ANTIGEN; GALACTOSE ANTIGEN; ISOLECTIN B4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY AFFINITY; ANTIGEN EXPRESSION; ARTICLE; CELLULAR DISTRIBUTION; ELECTRON MICROSCOPY; ENDOTHELIUM CELL; EPITOPE MAPPING; IMMUNOGOLD STAINING; IMMUNOHISTOCHEMISTRY; KIDNEY TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; SWINE;

ANIMALS; ANTIGENS, HETEROPHILE; BLOOD VESSELS; ENDOTHELIUM, VASCULAR; EPITOPES; GALACTOSE; IMMUNOHISTOCHEMISTRY; KIDNEY; LECTINS; MICROSCOPY, ELECTRON; NEPHRONS; PARAFFIN EMBEDDING; SUBCELLULAR FRACTIONS; SWINE; TISSUE FIXATION;

EID: 0345004079     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199812150-00013     Document Type: Article

References (40)

1. Niekrasz YYM, Kosanke S, Welsh R, et al. The pig as a potential organ donor for man. Transplantation 1994; 57: 694.
2. Good AH, Cooper DKC, Malcolm AJ, et al. Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans. Transplant Proc 1992; 24: 559.
3. Koren E, Kujundzic M, Koscec M, et al. Cytotoxic effects of human preformed anti-GAL IgG and complement on cultured pig cells. Transplant Proc 1994; 26: 1336.
4. Dalmasso AP. Role of complement in xenograft rejection. In: Cooper DKC, Kemp E, Platt JL, White DJG, eds. Xenotransplantation. New York: Springer Verlag, 1997: 38.
5. Rydberg L, Hallberg E, Björck S, et al. Studies on the removal of anti-pig xenoantibodies in the human by plasmapheresis/immunoadsorption. Xenotransplantation 1995; 2: 253.
6. McCurry KR, Kooyman DL, Alvarado CG, et al. Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury. Nat Med 1995; 1: 423.
7. Cozzi E, White DJG. The generation of transgenic pigs as potential organ donors for humans. Nat Med 1995; 1: 964.
8. Shinkel TA, Chen C-G, Salavaris E, et al. Changes in cell surface glycosylation in α1,3-galactosyltransferase knockout and α1,2-fucosyltransferase transgenic mice. Transplantation 1997; 64: 197.
9. Cohney S, McKenzie JFC, Patton K, et al. Down-regulation of Galα(1,3)Gal expression by α1,2-fucosyltransferase: further characterization of α1,2-fucosyltransferase transgenic mice. Transplantation 1997; 64: 495.
10. Oriol R, Ye Y, Koren E, Cooper DKC. Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation. Transplantation 1993; 56: 1433.
11. McKenzie IFC, Xing P-X, Vaughan HA, Prenzoska J, Dabkowski PL, Sandrin MS. Distribution of the major xenoantigen (Gal(α1-3)Gal) for pig to human xenografts. Transplant Immunol 1994; 2: 81.
12. Rydberg L, Björck S, Hallberg E, et al. Extra corporeal ("ex vivo") connection of pig kidneys to humans. II. The anti-pig antibody response. Xenotransplantation 1996; 3: 340.
13. Hallberg EC, Strokan V, Cairns TDH, Breimer ME, Samuelsson BE. Chemical and immunelectron microscopical studies of the expression of the Galα1-determinant in pig aorta. Xenotransplantation 1998; in press.
14. Tokuyasu KT. Application of cryoultramicrotomy to immunocytochemistry. J Microsc 1986; 143: 139.
15. Liou W, Geuze HJ, Slot JW. Improving structural integrity of cryosections for immunogold labeling. Histochem Cell Biol. 1996; 106: 41.
16. Boonstra J, van Bergen en Henegouwen PMP, van Belzen N, Rijken PJ, Verklej AJ. Immunogold labelling in combination with cryoultramicrotomy, freeze-etching, and label-fracture. J Microsc 1991; 161 (1): 135.
17. Roth J, Zuber C, Komminoth P, Sata T, Li W-P, Hetz PU. Applications of immunogold and lectin-gold labeling in tumor research and diagnosis. Histochem Cell Biol 1996; 106: 131.
18. Kriz W, Bankir L. A standard nomenclature for structures of the kidney: the Renal Commission of the International Union of Physiological Sciences (IUPS). Kidney Int 1988; 33: 1.
19. Kriz W, Kaissling B. Structural organization of the mammalian kidney. In: Seldin DW, Giebisch G, eds. The kidney: physiology and pathophysiology. New York: Raven Press, 1992: 707.
20. Lemley KV, Kriz W. Anatomy of the renal interstitium. Kidney Int 1991; 39: 370.
21. Moffat DB. The mammalian kidney. Cambridge: Cambridge University Press, 1975.
22. Bergelin ISS, Karlsson BW. Functional structure of the glomerular filtration barrier and the proximal tubuli in the developing foetal and neonatal pig kidney. Anat Embryol (Berl) 1975; 148: 223.
23. Elling F, Hasselager E, Friis C. Perfusion fixation of kidneys in adult pigs for electron microscopy. Acta Anat (Basel) 1977; 98: 340.
24. Friis C. Postnatal development of the pig kidney: ultrastructure of the glomerulus and the proximal tubule. J Anat 1980; 130: 513.
25. Dobyan DC, Bulger RE. The mammalian kidney. JAMA 1980; 244: 704.
26. Tiedemann K, Zaar K. The pig mesonephros. II. The proximal tubule: SEM, TEM and freeze-fracture images. Anat Embryol (Berl) 1983; 168: 241.
27. Cuttino JT, Jennette JC, Clark RL, Kwock L. Renal medullary lymphatics: microradiographic, light, and electron microscopic studies in pigs. Lymphology 1985; 18: 24.
28. Dobyan DC, Bulger RE. Morphology of the minipig kidney. J Electron Microsc Tech 1988; 9: 213.
29. Galili U, Shohet SB, Kobrin E, Stults CLM, Macher BA. Man, apes, and old world monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells. J Biol Chem 1988; 263: 17755.
30. Strokan V, Rydberg L, Hallberg EC, Mölne J, Breimer ME. Characterisation of human anti-sheep xenoantibodies. Xenotransplantation 1998; 5: 111.
31. Weibull C, Christiansson A, Carlemalm E. Extraction of membrane lipids during fixation, dehydration and embedding of Acholeplasma laidlawii cells for electron microscopy. J Microsc 1983; 129 (2): 201.
32. Oprins AD, Geuze HJ, Slot JW. Cryosubstitution dehydration of aldehyde-fixed tissue: a favorable approach to quantitative immunochemistry. J Histochem Cytochem 1994; 42: 497.
33. Kriz W, Elger M, Lemley K, Sakai T. Structure of the glomerular mesangium: a biomechanical interpretation. Kidney Int 1990; 38 (Suppl. 30): S2.
34. Roth J Subcellular organisation of glycosylation in mammalian cells. Biochim Biophys Acta 1987; 906: 405.
35. Holzknecht ZE, Platt JL. Identification of porcine endothelial cell membrane antigens recognized by human xenoreactive natural antibodies. J Immunol 1995; 154: 4565.
36. Gebrane-Younès J, Drouet L, Caen JP, Orcel L. Heterogeneous distribution of Weibel-Palade bodies and von Willebrand factor along the porcine vascular tree. Am J Pathol 1991; 139: 1471.
37. Gall JAM, Alcorn D, Butkus A, Coghlan JP, Ryan GB. Distribution of glomerular peripolar cells in different mammalian species. Cell Tissue Res 1986; 244: 203.
38. Zuber C, Sata T, Paulson JC, Roth J. Regional and cell-type specific expression of sialoglycoconjugates. Glycoconj J 1997; 14 (Suppl.1): S27.
39. Hamadeh RM, Galili U, Zhou P, Griffiss JM. Anti-α-galactosyl immunoglobulin A (IgA), IgG, and IgM in human secretions. Clin Diagn Lab Immunol 1995; 2: 125.
40. Oriol R, Barthod F, Bergemer A-M, Ye Y, Koren E, Cooper DKC. Monomorphic and polymorphic carbohydrate antigens on pig tissues: implications for organ xenotransplantation in the pig-to-human model. Transplant Int 1994; 7: 405.