Genetic modification of T-cell clones for therapy of human viral and malignant diseases

Cancer Journal from Scientific American

Volumn 4, Issue SUPPL. 1, 1998, Pages

  Greenberg, Philip D ^a   Finch, Rosalynde J ^a   Gavin, Marc A ^a   Kalos, Michael ^a   Lewinsohn, Deborah A ^a   Lonergan, Matthew ^a   Lord, James D ^a   Nelson, Brad H ^a   Öhlén, Claes ^a   Sing, Amy P ^a   Warren, Edus H ^a   Yee, Cassian ^a   Riddell, Stanley R ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENE INDUCTION; GENE THERAPY; HUMAN; IMMUNOTHERAPY; LYMPHOCYTE CLONE; MALIGNANT NEOPLASTIC DISEASE; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS INFECTION;

ADOPTIVE TRANSFER; BONE MARROW TRANSPLANTATION; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CLONE CELLS; CYTOMEGALOVIRUS INFECTIONS; GENE TRANSFER TECHNIQUES; HIV INFECTIONS; HUMANS; LEUKEMIA; MODELS, BIOLOGICAL; NEOPLASMS; T-LYMPHOCYTES; VIRUS DISEASES;

EID: 0344972951     PISSN: 10814442     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Riddell SR, Greenberg PD. Principles for adoptive T cell therapy of human viral diseases. Ann Rev Immunol 1995;13:545-586
2. Gilbert MJ, Riddell SR, Plachter B et al. Cytomegalovirus prevents antigen processing and presentation of its immediate early gene product. Nature 1996;383:720-722.
3. Walter EA, Greenbert PD, Gilbert MJ et al. Reconstitution of cellular immunity against CMV in recipients of allogeneic bone marrow by adoptive transfer of T cell clones from the donor. N Engl J Med 1995;333:1038-1044.
4. Riddell SR, Elliot M, Lewinsohn DA et al. Administration of gene-modified CD8+ HIV-specific CTL clones to HIV+ patients: CD8+ T cell responses to the transgene product limit persistence of transferred genes. Nat Med 1996;2:216-223.
5. Sing AP, Ambinder RF, Hong DJ et al. Isolation of Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes that lyse Reed-Sternberg cells: implications for immune-mediated therapy of EBV+ Hodgkin's disease. Blood 1997;89:1978-1986.
6. Nelson B, Lord JD, Greenberg PD. Cytoplasmic domains of the IL-2 receptor β and γ chains mediate the signal for T-cell proliferation. Nature 1994;369:333-336.
7. Yee C, Gibert MJ, Riddell SR et al. Isolation of tyrosinase-specific CD8+ and CD4+ cell clones from the peripheral blood of melanoma patients following in vitro stimulation with recombinant vaccinia virus. J Immunol 1996;157:4079-4086.