An essential saccharide binding domain for the mAb 2C7 established for Neisseria gonorrhoeae LOS by ES-MS and MS(n)

Glycobiology

Volumn 9, Issue 2, 1999, Pages 157-171

  Mühlecker, Walter ^a   Gulati, Sunita ^b   McQuillen, Daniel P ^b   Ram, Sanjay ^b   Rice, Peter A ^a,b   Reinhold, Vernon N ^a,c  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON MEDICAL CENTER   (United States)

^c Univ of New Hampshire   (United States)

Author keywords

ES MS(n); Gonorrhoeae; MAb 2C7; Oligosaccharide

Indexed keywords

ACID; ANTIGEN; BACTERIAL POLYSACCHARIDE; EPITOPE; GLYCOSIDE; HYDRAZINE; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; OLIGOSACCHARIDE; VACCINE;

ANTIGEN BINDING; ARTICLE; GENE EXPRESSION; GONORRHEA; HYDROLYSIS; MASS SPECTROMETRY; MEMBRANE COMPONENT; NEISSERIA GONORRHOEAE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN BINDING; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; ANTIGENS, BACTERIAL; BINDING SITES; CARBOHYDRATE SEQUENCE; EPITOPES; LIPOPOLYSACCHARIDES; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; NEISSERIA GONORRHOEAE; SPECIES SPECIFICITY;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; NEISSERIA GONORRHOEAE;

EID: 0344959649     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/9.2.157     Document Type: Article

References (36)

1. Asam, M.R. and Glish, G.L. (1997) Tandem mass spectrometry of alkali cationized oligosaccharides in a quadrupole ion trap. J. Amer. Soc. Mass Spectrom., 8, 987-995.
2. Ashford, W.A., Golash, R.G. and Hemming, V.G. (1976) Penicillinase-producing Neisseria gonorrhoeae. Lancet, 2, 657-658.
3. Burch, C.L., Danaher, R.J. and Stein, D.C. (1997) Antigenic variation in Neisseria gonorrhoeae: production of multiple lipooligosaccharides J. Bacteriol., 179, 982-986.
4. Carbillo, M., Pause, M. and Dillon, J.R. (1990) Increase of Neisseria gonorrhoeae isolates with combined plasmid-mediated resistance to tetracycline and penicillin. Can. Dis. Wkly. Rep., 16, 219-222.
5. Ciucanu, I. and Kerek, F. (1984) A Simple and rapid method for the permethylation of carbohydrates. Carbohydr. Res., 131, 209-217.
6. Densen, P., Gulati, S. and Rice, P. (1987) Specificity of antibodies against Neisseria gonorrhoeae lipopolysaccharide antigens that stimulate neutrophil chemotaxis. J. Clin. Invest., 80, 78-87.
7. Erwin, A.L., Haynes, P.A., Rice, P.A. and Gotschlich, E.C. (1996) Conservation of the lipopolysaccharide synthesis locus lgt among strains of Neisseria gonorrhoeae: requirement for lgtE in synthesis of the 2C7 epitope and of the beta chain of strain 15253. J. Exp. Med., 184, 1233-1241.
8. Gascoyne-Binzi, D.M., Hawkey, P.M., Heritage, J., Turner, A. and Nadarajah, M. (1992) Worldwide distribution of high level tetracycline-resistant Neisseria gonorrhoeae. Genitourin Med., 68, 277-278.
9. Gibson, B.W., Webb, J.W., Yamasaki, R., Fisher, S.J., Burlingame, A.L., Mandrell, R.E., Schneider, H. and Griffiss, J.M. (1989) Structure and heterogeneity of the oligosaccharides from the lipopolysaccharides of a pyocin-resistant Neisseria gonorrhoeae. Proc. Natl. Acad. Sci. USA, 86, 17-21.
10. Gibson, B.W., Melaugh, W., Phillips, N.J., Apicella, M.A., Campagnari, A.A. and Griffiss, J.M. (1993) Investigation of the structural heterogeneity of lipooligosaccharides from pathogenic Haemophilus and Neisseria species and of R-type lipopolysaccharides from Salmonella typhimurium by electrospray mass spectrometry. J. Bacteriol., 175, 2702-2712.
11. Griffiss, J.M., O'Brien, J.P., Yamasaki, R. and Williams, G.D. (1987) Physical heterogeneity of neisserial lipopolysaccharides reflects oligosaccharides that differ in apparent molecular weight, chemical composition, and antigenic expression. Infect. Immun., 55, 1792-1800.
12. Gulati, S., Mcquillen, D.P., Sharon, J. and Rice, P.A. (1996) Experimental immunization with a monoclonal anti-idiotope antibody that mimics the Neisseria gonorrhoeae lipooligosaccharide epitope 2C7. J. Infect. Dis., 174, 1238-1248.
13. Gulati, S., McQuillen, D.P., Mandrell, R.E., Jani, D.B. and Rice, P.A. (1997) Immunogenicity of Neisseria gonorrhoeae lipooligosaccharide epitope 2C7, widely expressed in vivo with no immunochemical similarity to human glycosphingolipids. J. Infect. Dis., 175, 1027-1027.
14. Hamett, N., Brown, S., Terro, R., Krishnan, C., Pauze, R. and Yeung, K.H. (1997) High-level tetracycline-resistant Neisseria gonorrhoeae in Ontario, Canada -investigation of a cluster of isolates, showing chromosomally mediated resistance to penicillin combined with plasmid-mediated resistance to tetracycline. J. Infect. Dis., 176, 1269-1276.
15. James, J.F. and Swanson, J. (1978) Studies on gonococcus infection. 12. Occurrence of color/opacity colonial variants in clinical cultures. Infect. Immun., 19, 332-340.
16. John, C.M., Griffiss, J.M., Apicella, M.A., Mandrell, R.E. and Gibson, B.W. (1991) The structural basis for pyocin resistance in Neisseria gonorrhoeae lipooligosaccharides. J. Biol. Chem., 266, 19303-19311.
17. Jonscher, K.R. and Yates, J.R. (1997) The quadrupole ion trap mass spectrometer - a small solution to a big challenge. Anal. Biochem., 244, 1-15.
18. Mandrell, R.E., Schneider, H., Apicella, M., Zollinger, W., Rice, P.A. and Griffiss, J.M. (1986) Antigenic and physical diversity of Neisseria gonorrhoeae lipopolysaccharides. Infect. Immunol., 54, 63-69.
19. Mandrell, R.E., Griffiss, J.M. and Macher, B.A. (1988) Lipooligosaccharides (LOS) of Neisseria gonorrhoeoe and Neisseria meningitidis have components that are immunochemically similar to precursors of human blood group antigens. Carbohydrate sequence specificity of the mouse monoclonal antibodies that recognize crossreacting antigens on LOS and human erythrocytes. J. Exp. Med., 168, 107-126.
20. March, R.E. (1997) An introduction to quadrupole ion trap mass spectrometry. J. Mass Spectrom., 32, 351-369.
21. Mason, P.R., Gwanzura, L., Latif, A.S., Marowa, E., Ray, S. and Katzenstein, D.A. (1998) Antimicrobial resistance in gonococci isolated from patients and from commercial sex workers in Harare, Zimbabwe. Int. J. Antimicrob. Agents, 9, 175-179.
22. McQuillen, D.P., Gulati, S. and Rice, P.A. (1994) Complement-mediated baterial killing assays. Methods Enzymol., 236, 137-147.
23. Morse, S.A., Johnson, S.R., Biddle, J.W. and Roberts, M.C. (1986) High level tetracycline resistance in Neisseeria gonorrhoeae is the result of acquisition of streptococcal tetM determinant. Antimicrob. Agents Chemother., 30, 664-670.
24. Nissinen, A., Jarvinen, H., Liimatainen, O., Jahkola, M., Huovinen, P., Eerola, E., Eskola, J., Hiekkaniemi, H., Jagerroos, H., Katila, M.L., Kauppinen, M., Klossner, M.L., Kontiainen, S., Korpela, J., Koskela, M., KostialaThompson, A., Karkkainen, P., Lantto, K., Larinkari, U., Lehtonen, O.P., Meurman, O., Oinonen, S., Pietarinen, I., Ratia, V., Ruuska, P., Sarkkinen, H., Schauman, K., Sivonen, A., Vaara, M. and Vuento, R. (1997) Antimicrobial resistance in Neisseria gonorrhoeae in Finland, 1976 to 1995. Sex Transm. Dis., 24, 576-581.
25. Reinhold, V.N. (1972) Gas-liquid Chromatographic analysis of constituent carbohydrates in glycoproteins. Method Enzymol., 25, 244-249.
26. Reinhold, B.B. and Reinhold, V.N. (1992) Electrospray ionization mass spectrometry: deconvolution by an entropy based algorithm. J. Am. Soc. Mass Spectrom., 3, 207-215.
27. Reinhold, V.N. and Sheeley, D.M. (1998) Detailed characterization of carbohydrate linkage and sequence in an ion trap mass spectrometer: glycosphingolipids. Anal. Biochem., 259, 28-33.
28. Reinhold, V.N., Reinhold, B.B. and Costello, C.E. (1995) carbohydrate molecular weight profiling, sequence, linkage, and branching data: ES-MS and CID. Anal. Chem., 67, 1772-1784.
29. Reinhold, V.N., Reinhold, B.B. and Chan, S. (1996) Carbohydrate sequence analysis (ES-MS-CID-MS). Methods Enzymol., 270, 377-102.
30. Schwartz, J.C. and Jardine, I. (1996) Quadrupole ion trap mass spectrometry. Methods Enzymol, 270, 522-586.
31. Sheeley, D.M. and Reinhold, V.N. (1998) Detailed structural characterization of carbohydrate sequence, linkage, and branching in a quadrupole ion-trap mass spectrometer: neutral oligosaccharides and N-linked glycans. Anal. Chem 70. in press.
32. Schmidt, G., Jann, B. and Jann, K. (1969) Immunochemistry of R lipopolysaccharides of Escherichia coli. Different core regions in the lipopolysaccharides of O group 8. Eur J. Biochem., 10, 501-510.
33. West, S.E.H. and Clark, V.L. (1989) Genetic loci and linkage associations in Neisseria gonorrhoeae and Neisseria meningitidis. Clin. Microbiol. Rev., 2, S92-S103.
34. Westphal, O., Luderitz, O. and Bister, F. (1952) Uber die Extraktion von Bacterien mit phenol/Wasser. Z. Naturforsch. B. 7, 148-155.
35. Yamasaki, R., Bacon, B.E., Nasholds, W., Schneider, H. and Griffiss, J.M. (1991) Structural determination of oligosaccharides derived from lipooligosaccharide of Neisseria gonorrhoeae F62 by chemical, enzymatic, and two-dimensional NMR methods [published erratum appears in Biochemistry: 1992, 31, 316]. Biochemistry, 30, 10566-10575.
36. Yang, Q.L. and Gotschlich, E.C. (1996) Variation of gonococcal lipooligosaccharide structure is due to alterations in poly-G tracts in lgt genes encoding glycosyl transferases. J. Exp. Med., 183, 323-327.