Structure-activity relationship of furosemide-derived compounds as antagonists of cerebellum-specific GABA(A) receptors

European Journal of Pharmacology

Volumn 344, Issue 2-3, 1998, Pages 269-277

  Lüddens, Hartmut ^a   Lang, Hans J ^b   Korpi, Esa R ^c  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b SANOFI   (France)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

35S TBPS( 35S t butylbicyclophosphorothionate); Cerebellum; Diuretic; Furosemide; GABA(A) receptor; Subtypes

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; AZOSEMIDE; BUMETANIDE; CHLORIDE ION; DIURETIC AGENT; FUROSEMIDE; FUROSEMIDE DERIVATIVE; HYDRAZINOSULFONYL FUROSEMIDE; INDACRINONE; PHOSPHONIC ACID DERIVATIVE; POTASSIUM ION; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT; SODIUM ION; SULFONAMIDE; SULFONIC ACID DERIVATIVE; TERT BUTYLBICYCLOPHOSPHOROTHIOATE; TIENILIC ACID; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CEREBELLUM; CHANNEL GATING; CHLORIDE CURRENT; CONTROLLED STUDY; DIURESIS; DRUG MECHANISM; DRUG POTENCY; GABAERGIC SYSTEM; GRANULE CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CEREBELLUM; CEREBRAL CORTEX; FUROSEMIDE; MALE; RATS; RATS, WISTAR; RECEPTORS, GABA-A; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0344936061     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01577-X     Document Type: Article

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