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and references therein
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An alternative protocol for C-N bond formation is the amination of arylhalides catalyzed by Cu(I) salts developed by Buchwald. This highly efficient method tolerates a broad range of substrates, but reactions are performed at elevated temperatures, and in the presence of several equivalents of base. See: Kwong, F. Y.; Buchwald, S. L. Org. Lett. 2003, 5, 793-796 and references therein.
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Kwong, F.Y.1
Buchwald, S.L.2
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For a recent review on Cu(OAc)2-mediated arylation of heteroatomic nucleophiles using aryl-B, Bi, Pb, Si, and Sn and hypervalent iodonium reagents, see: Finet, J. P.; Fedorov, A. Y.; Combes, S.; Boyer, G. Curr. Org. Chem. 2002, 6, 597-626.
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2, and several are now commercially available. See: Vedejs, E.; Fields, S. C.; Schrimpf, M. R. J. Am. Chem. Soc. 1993, 115, 11612-11613.
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Vedejs, E.1
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16
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0344847471
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note
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2 for 24 h. The reaction mixture was then filtered through a plug of Celite and the product isolated by column chromatography (see the Supporting Information).
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