Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity

Nucleic Acids Research

Volumn 31, Issue 17, 2003, Pages 5016-5024

  Mondal, Neelima ^a   Zhang, Ye ^a   Jonsson, Zophonias ^a   Dhar, Suman Kumar ^a   Kannapiran, Madhu ^a   Parvin, Jeffrey D ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); HISTONE; RNA POLYMERASE II;

ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; PRIORITY JOURNAL; RNA SYNTHESIS; RNA TRANSLATION; TRANSCRIPTION REGULATION; YEAST;

CAMPTOTHECIN; CHROMATIN; DNA; DNA TOPOISOMERASES; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; ETOPOSIDE; HELA CELLS; HUMANS; NUCLEIC ACID CONFORMATION; NUCLEIC ACID SYNTHESIS INHIBITORS; NUCLEOSOMES; RNA; RNA POLYMERASE II; TEMPLATES, GENETIC; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS);

EID: 0344875486     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg705     Document Type: Article

References (33)

1. Hampsey, M. (1998) Molecular genetics of the RNA polymerase II general transcriptional machinery. Microbiol. Mol. Biol. Rev., 62, 465-503.
2. LeRoy, G., Orphanides, G., Lane, W.S. and Reinberg, D. (1998) Requirement of RSF and FACT for transcription of chromatin templates in vitro. Science, 282, 1900-1904.
3. Mondal, N. and Parvin, J.D. (2001) DNA topoisomerase IIalpha is required for RNA polymerase II transcription on chromatin templates. Nature, 413, 435-438.
4. Owen-Hughes, T. and Workman, J.L. (1994) Experimental analysis of chromatin function in transcription control. Crit. Rev. Eukaryot. Gene Expr., 4, 403-441.
5. Liu, L.F. and Wang, J.C. (1987) Supercoiling of the DNA template during transcription. Proc. Natl Acad. Sci. USA, 84, 7024-7027.
6. Wang, J.C. (1996) DNA topoisomerases. Annu. Rev. Biochem., 65, 635-692.
7. Brill, S.J., DiNardo, S., Voelkel-Meiman, K. and Sternglanz, R. (1987) Need for DNA topoisomerase activity as a swivel for DNA replication for transcription of ribosomal RNA. Nature, 326, 414-416.
8. Yamagishi, M. and Nomura, M. (1988) Deficiency in both type I and type II DNA topoisomerase activities differentially affect rRNA and ribosomal protein synthesis in Schizosaccharomyces pombe. Curr. Genet., 13, 305-314.
9. Gartenberg, M.R. and Wang, J.C. (1992) Positive supercoiling of DNA greatly diminishes mRNA synthesis in yeast. Proc. Natl Acad. Sci. USA, 89, 11461-11465.
10. Schultz, M.C., Brill, S.J., Ju, Q., Sternglanz, R. and Reeder, R.H. (1992) Topoisomerases and yeast rRNA transcription: negative supercoiling stimulates initiation and topoisomerase activity is required for elongation. Genes Dev., 6, 1332-1341.
11. Collins, I., Weber, A. and Levens, D. (2001) Transcriptional consequences of topoisomerase inhibition. Mol. Cell. Biol., 21, 8437-8451.
12. Manley, J.L., Fire, A., Samuels, M. and Sharp, P.A. (1983) In vitro transcription: whole-cell extract. Methods Enzymol., 101, 568-582.
13. Workman, J.L., Taylor, I.C., Kingston, R.E. and Roeder, R.G. (1991) Control of class II gene transcription during in vitro nucleosome assembly. Methods Cell Biol., 35, 419-447.
14. Ito, T., Levenstein, M.E., Fyodorov, D.V., Kutach, A.K., Kobayashi, R. and Kadonaga, J.T. (1999) ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly. Genes Dev., 13, 1529-1539.
15. Zhelkovsky, A.M. and Moore, C.L. (1994) Overexpression of human DNA topoisomerase I in insect cells using a baculovirus vector. Protein Expr. Purif., 5, 364-370.
16. Haile, D.T. and Parvin, J.D. (1999) Activation of transcription in vitro by the BRCA1 carboxyl-terminal domain. J. Biol. Chem., 274, 2113-2117.
17. Chiang, C.M. and Roeder, R.G. (1993) Expression and purification of general transcription factors by FLAG epitope-tagging and peptide elution. Pept. Res., 6, 62-64.
18. Kretzschmar, M., Kaiser, K., Lottspeich, F. and Meisterernst, M. (1994) A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators. Cell, 78, 525-534.
19. Jonsson, Z.O., Dhar, S.K., Narlikar, G.J., Auty, R., Wagle, N., Pellman, D., Pratt, R.E., Kingston, R. and Dutta, A. (2001) Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J. Biol. Chem., 276, 16279-16288.
20. Kretzschmar, M., Meisterernst, M. and Roeder, R.G. (1993) Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. Proc. Natl Acad. Sci. USA, 90, 11508-11512.
21. Merino, A., Madden, K.R., Lane, W.S., Champoux, J.J. and Reinberg, D. (1993) DNA topoisomerase I is involved in both repression and activation of transcription. Nature, 365, 227-232.
22. Lin, Y.S., Ha, I., Maldonado, E., Reinberg, D. and Green, M.R. (1991) Binding of general transcription factor TFIIB to an acidic activating region. Nature, 353, 569-571.
23. Shykind, B.M., Kim, J., Stewart, L., Champoux, J.J. and Sharp, P.A. (1997) Topoisomerase I enhances TFIID-TFIIA complex assembly during activation of transcription. Genes Dev., 11, 397-407.
24. Wang, J.C. and Lynch, A.S. (1993) Transcription and DNA supercoiling. Curr. Opin. Genet. Dev., 3, 764-768.
25. Fleischmann, G., Pflugfelder, G., Steiner, E.K., Javaherian, K., Howard, G.C., Wang, J.C. and Elgin, S.C. (1984) Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome. Proc. Natl Acad. Sci. USA, 81, 6958-6962.
26. Egyhazi, E. and Durban, E. (1987) Microinjection of anti-topoisomerase I immunoglobulin G into nuclei of Chironomus tentans salivary gland cells leads to blockage of transcription elongation. Mol. Cell. Biol., 7, 4308-4316.
27. Zhang, H., Wang, J.C. and Liu, L.F. (1988) Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes. Proc. Natl Acad. Sci. USA, 85, 1060-1064,
28. Lorch, Y., LaPointe, J.W. and Kornberg, R.D. (1987) Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones. Cell, 49, 203-210.
29. Izban, M.G. and Luse, D.S. (1992) Factor-stimulated RNA polymerase II transcribes at physiological elongation rates on naked DNA but very poorly on chromatin templates. J. Biol. Chem., 267, 13647-13655.
30. Havas, K., Flaus, A., Phelan, M., Kingston, R., Wade, P.A., Lilley, D.M. and Owen-Hughes, T. (2000) Generation of superhelical torsion by ATP-dependent chromatin remodeling activities. Cell, 103, 1133-1142.
31. Jensen, L.H., Nitiss, K.C., Rose, A., Dong, J., Zhou, J., Hu, T., Osheroff, N., Jensen, P.B., Sehested, M. and Nitiss, J.L. (2000) A novel mechanism of cell killing by anti-topoisomerase II bisdioxopiperazines. J. Biol, Chem., 275, 2137-2146.
32. Liu, L.F. (1989) DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem., 58, 351-375.
33. Sullivan, D.M., Glisson, B.S., Hodges, P.K., Smallwood-Kentro, S. and Ross, W.E. (1986) Proliferation dependence of topoisomerase II mediated drug action. Biochemistry, 25, 2248-2256.