Altered responses of chondrocytes to nanophase PLGA/nanophase titania composites

Biomaterials

Volumn 25, Issue 7-8, 2004, Pages 1205-1213

  Savaiano, Jennifer K ^a   Webster, Thomas J ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

Cartilage; Chondrocytes; Nanophase; Poly lactic glycolic acid; Titania

Indexed keywords

BONE; CELLS; ENZYME KINETICS; INTERFACES (MATERIALS); PROTEINS; SURFACES; SYNTHESIS (CHEMICAL); TITANIUM DIOXIDE;

INTRACELLULAR SYNTHESIS;

COMPOSITE MATERIALS;

ALKALINE PHOSPHATASE; CELL PROTEIN; GLYCOLIC ACID; NANOPARTICLE; POLYLACTIC ACID; SODIUM HYDROXIDE; TITANIUM DERIVATIVE; TITANIUM DIOXIDE;

ARTICLE; BONE CELL; CARTILAGE CELL; CELL DENSITY; CELL FUNCTION; CERAMICS; CONTROLLED STUDY; FILM; GRAIN; HUMAN; HUMAN CELL; IN VITRO STUDY; NANOTECHNOLOGY; PRIORITY JOURNAL; STRUCTURE ANALYSIS; SURFACE PROPERTY; SYNTHESIS; TOPOGRAPHY;

EID: 0344825277     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2003.08.012     Document Type: Article

References (24)

1. Makin H.J., Mow V.C., Buckwalter J.A., Iannotti J.P., Ratcliffe A. Form and function of articular cartilage. Simon S.R. Orthopaedic basic science. 1994;127-143 Am. Acad. Orth. Surg. Columbus, OH.
2. Buckwalter J.A., Mankin H.J. Articular cartilage Part II. degeneration and oseoarthrosis, repair, regeneration, and transplantation J Bone Jt Surg. 79:1997;612.
3. Hutmacher D.A. Scaffolds in tissue engineering bone and cartilage. Biomaterials. 21:2000;2529.
4. Bostman O., Viljanen J., Salminen S., Pihlajamaki H. Response of articular cartilage and subchondral bone to internal fixation devices made of poly L-lactide. a histomorphometric and microradiographic study on rabbits Biomaterials. 21:2000;2553.
5. Suh F.J.K., Matthew W.T.H. Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering. a review Biomaterials. 21:2000;2589.
6. Scaefer D., Martin I., Shastri P., Padera R.F., Langer R., Freed L.E., Vunjak-Novakovic G. In vitro generation of osteochondral composites. Biomaterials. 21:2000;2599.
7. LeBaron R.G., Athanasiou K.A. Ex vivo synthesis of articular cartilage. Biomaterials. 21:2000;2575.
8. Rahfoth B., Weisser J., Sternkopf F., Aigner T., von der Mark K., Brauer R. Transplantation of allograft chondrocytes embedded in agarose gel into cartilage defects in rabbits. Osteoarthritis Cartilage. 6:1998;50.
9. Guidolin D.D., Ronchetti I.P., Lini E., Guerra D., Frizziero L. Morphological analysis of articular cartilage biopsies from a randomized, clinical study comparing the effects of 500-730. kDa sodium hyaluronate (Hyalgan) and methylprednisolone acetate on primary osteoarthritis of the knee Osteoarthritis Cartilage. 9:2001;371.
10. Mikos A., Thorsen A., Czerwonka L., Boa Y., Winslow D., Vancanti J., Langer R. Preparation and characterization of poly(L-lactic acid) foams for cell transplantation. Polymer. 35:1994;1068.
11. Gao J., Niklason L., Langer R. Surface hydrolysis of poly(glycolic acid) meshes increases the seeding density of vascular smooth muscle cells. J Biomed Mater Res. 42:1998;417.
12. Kay S., Thapa A., Haberstroh K.M., Webster T.J. Nanostructured polymer. nanophase ceramic composites enhance osteoblast and chondrocyte adhesion Tissue Eng. 8:2002;753.
13. Thapa A, Webster TJ, Haberstroh KM. An investigation of nano-structured polymers for use as bladder tissue replacement constructs. Mater Res Soc Symp Proc 2002;711:GG3.4.1.
14. Miller DM, Thapa A, Haberstroh KM, Webster TJ. An in vitro study of nano-fiber polymers for guided vascular regeneration. Mater Res Soc Symp Proc 2002; 711:GG3.2.1.
15. Kim H.M., Miyaji F., Kokubo T., Nishiguchi S., Nakamura T. Graded surface structure of bioactive titanium prepared by chemical treatment. J Biomed Mater Res. 45:1999;100.
16. Thapa A, Webster TJ, Haberstroh KM. Polymers with nanodimensional surface features enhance bladder smooth muscle cell adhesion. J Biomed Mater Res, in press.
17. Webster T.J., Siegel R.W., Bizios R. Osteoblast adhesion on nanophase ceramics. Biomaterials. 20:1999;1222.
18. Lowry O.H., Roberts N.R., Wu M., Hixton W.S., Crawford E.J. The quantitative histochemistry of the brain III. Enzyme measurements. J Bio Chem. 207:1954;19.
19. Steck E., Benz K., Lorenz H., Loew M., Gress T., Richter W. Chondrocyte expressed protein-68 (CEP-68), a novel human marker gene for cultured chondrocytes. Biochem J. 353:2001;169.
20. Ayad S, Boot-Handford R, Humphries MJ, Kadler KE, and Shuttleworth A. The extracellular matrix factsbook. San Diego, CA: Academic Press, Inc.; 1994. p. 29-149.
21. Webster T.J., Siegel R.W., Bizios R. Enhanced functions of osteoblasts on nanophase ceramics. Biomaterials. 21:2000;1803.
22. Webster T.J., Ergun C., Doremus R.H., Siegel R.W., Bizios R. Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics. J Biomed Mater Res. 51:2000;475.
23. Webster T.J., Schadler L.S., Siegel R.W., Bizios R. Mechanisms of enhanced osteoblast adhesion on nanophase alumina involve vitronectin. Tissue Eng. 7:2001;291.
24. Webster T.J., Ergun C., Doremus R.H., Siegel R.W., Bizios R. Enhanced functions of osteoclast-like cells on nanophase ceramics. Biomaterials. 22:2001;1327.