Synthetic lethal interactions with conditional poly(A) polymerase alleles identify LCP5, a gene involved in 18S rRNA maturation

RNA

Volumn 4, Issue 11, 1998, Pages 1357-1372

  Wiederkehr, Thomas ^a   Prétôt, René F ^a   Minvielle Sebastia, Lionel ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Ribosome biogenesis; Translation; U3 snoRNP

Indexed keywords

MESSENGER RNA; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; RIBONUCLEOPROTEIN; RNA 18S;

ARTICLE; GENE ISOLATION; GENE MUTATION; LETHAL MUTANT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RNA CLEAVAGE; RNA PROCESSING; SACCHAROMYCES CEREVISIAE;

ALLELES; AMINO ACID SEQUENCE; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; DNA-BINDING PROTEINS; FUNGAL PROTEINS; GENES, ESSENTIAL; GENES, FUNGAL; GENES, LETHAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEAR PROTEINS; PHENOTYPE; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; POLYRIBOSOMES; PROTEIN BIOSYNTHESIS; RIBOSOMES; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, FUNGAL; RNA, RIBOSOMAL, 18S; RNA, SMALL NUCLEAR; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES POMBE PROTEINS;

FUNGI; MYXOGASTRIA; SACCHAROMYCES CEREVISIAE;

EID: 0344765459     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838298980955     Document Type: Article

References (70)

1. 3 is linked. RNA 2:63-73.
2. Baudin-Baillieu A, Guillemet E, Cullin C, Lacroute F. 1997. Construction of a yeast strain deleted for the TRP1 promoter and coding region that enhances the efficiency of the polymerase chain reaction-disruption method. Yeast 13:353-356.
3. Beltrame M, Tollervey D. 1995. Base pairing between U3 and the pre-ribosomal RNA is required for 18S rRNA synthesis. EMBO J 14:4350-4356.
4. Caponigro G, Parker R. 1995. Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast. Genes & Dev 9:2421-2432.
5. Colgan DF, Manley JL. 1997. Mechanism and regulation of mRNA polyadenylation. Genes & Dev 11:2755-2766.
6. Collart MA, Oliviero S. 1994. Preparation of Yeast RNA. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, eds. Current Protocols in Molecular Biology. New York: Current Protocols, pp 13.12.1-13.12.2.
7. Dingwall C, Laskey RA. 1991. Nuclear targeting sequences - a consensus? Trends Biochem Sci 16:478-481.
8. Doye V, Hurt E. 1997. From nucleoporins to nuclear pore complexes. Curr Opin Cell Biol 9:401-411.
9. Dunbar DA, Wormsley S, Agentis TM, Baserga SJ. 1997. Mpp10p, a U3 small nucleolar ribonucleoprotein component required for pre-18S rRNA processing in yeast. Mol Cell Biol 17:5803-5812.
10. Elela SA, Igel H, Ares M. 1996. RNase III cleaves eukaryotic preribosomal RNA at a U3 snoRNP-dependent site. Cell 85:115-124.
11. Eustice DC, Wilhelm JM. 1984a. Fidelity of the eucaryotic codon-anticodon interaction: Interference by aminoglycoside antibiotics. Biochemistry 23:1462-1467.
12. Eustice DC, Wilhelm JM. 1984b. Mechanisms of action of aminoglycoside antibiotics in eucaryotic protein synthesis. Antimicrob Agents Chemother 26:53-60.
13. Frank D, Patterson B, Guthrie C. 1992. Synthetic lethal mutations suggest interactions between U5 small nuclear RNA and four proteins required for the second step of splicing. Mol Cell Biol 12:5197-5205.
14. Gallie DR. 1991. The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency. Genes & Dev 5:2108-2116.
15. Gallie DR, Tanguay R. 1994. Poly(A) binds to initiation factors and increases cap-dependent translation in vitro. J Biol Chem 269: 17166-17173.
16. Ganot P, Caizergues-Ferrer M, Kiss T. 1997. The family of box ACA small nucleolar RNAs is defined by an evolutionary conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation. Genes & Dev 11:941-956.
17. Gietz D, St Jean A, Woods RA, Schiestl RH. 1992. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res 20:1425.
18. Guarente L. 1993. Synthetic enhancement in gene interaction: A genetic tool come of age. Trends Genet 9:362-366.
19. Guthrie C, Fink GR. 1991. Guide to Yeast Genetics and Molecular Biology. San Diego, California: Academic Press.
20. Haghighat A, Sonenberg N. 1997. elF4G dramatically enhances the binding of elF4E to the mRNA 5′-cap structure. J Biol Chem 272:21677-21680.
21. Hampsey M. 1997. A review of phenotypes in Saccharomyces cerevisiae. Yeast 13:1099-1133.
22. Harlow E, Lane D. 1988. Antibodies: A laboratory manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
23. Huffacker TC, Hoyt MA, Botstein D. 1987. Genetic analysis of the yeast cytoskeleton. Annu Rev Genet 21:259-284.
24. Hughes JMX, Ares M. 1991. Depletion of U3 small nucleolar RNA inhibits cleavage in the 5′ external transcribed spacer of yeast pre-ribosomal RNA and impairs formation of 18S ribosomal RNA. EMBO J 10:4231-4239.
25. Jacobson A, Peltz SW. 1996. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. Annu Rev Biochem 65:693-739.
26. Jansen R, Tollervey D, Hurt EC. 1993. A U3 snoRNP protein with homology to splicing factor PRP4 and Gβ domains is required for ribosomal RNA processing. EMBO J 12:2549-2558.
27. Jenny A, Minvielle-Sebastia L, Preker PJ, Keller W. 1996. Sequence similarity between the 73-kilodalton protein of mammalian CPSF and a subunit of yeast polyadenylation factor I. Science 274:1514-1517.
28. Keller W. 1995. No end yet to messenger RNA 3′ processing! Cell 81:829-832.
29. Keller W, Minvielle-Sebastia L. 1997. A comparison of mammalian and yeast pre-mRNA3′-end processing. Curr Opin Cell Biol 9:329-336.
30. Kessler MM, Henry MF, Shen E, Zhao J, Gross S, Silver PA, Moore CL. 1997. Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3′-end formation in yeast. Genes & Dev 11:2545-2556.
31. Kessler MM, Zhao J, Moore CL. 1996. Purification of the Saccharomyces cerevisiae cleavage/polyadenylation factor I. J Biol Chem 271:27167-27175.
32. Kressler D, de la Cruz J, Rojo M, Linder P. 1997. Fal1p is an essential DEAD-box protein involved in 40S-ribosomal-subunit biogenesis in Saccharomyces cerevisiae. Mol Cell Biol 17:7283-7294.
33. Lee W-C, Zabetakis D, Mélèse T. 1992. NSR1 is required for pre-rRNA processing and for the proper maintenance of steady-state levels of ribosomal subunits. Mol Cell Biol 12:3865-3871.
34. Li HV, Zagorski J, Fournier MJ. 1990. Depletion of U14 small nuclear RNA (snR128) disrupts production of 18S rRNA in Saccharomyces cerevisiae. Mol Cell Biol 10:1145-1152.
35. Lingner J. 1992. Biochemical and genetic analysis of poly(A) polymerase from Saccharomyces cerevisiae. Doctoral thesis. University of Basel, Basel, Switzerland.
36. Lupas A, Van Dyke M, Stock J. 1991. Predicting coiled coils from protein sequences. Science 252:1162-1164.
37. Lygerou Z, Allmang C, Tollervey D, Séraphin B. 1996. Accurate processing of a eukaryotic precursor ribosomal RNA by ribonuclease MRP in vitro. Science 272:268-270.
38. Manley JL, Takagaki Y. 1996. The end of the message-another link between yeast and mammals. Science 274:1481-1482.
39. Martens JA, Genereaux J, Saleh A, Brandi CJ. 1996. Transcriptional activation by yeast PDR1p is inhibited by its association with NGG1p/ADA3p. J Biol Chem 271:15884-15890.
40. Martin G, Keller W. 1996. Mutational analysis of mammalian poly(A) polymerase identifies a region for primer binding and a catalytic domain, homologous to the family X polymerases, and to other nucleotidyltransferases. EMBO J 15:2593-2603.
41. Mewes HW, Albermann K, Heumann K, Liebl S, Pfeiffer F. 1997. MIPS: A database for protein sequences, homology data and yeast genome information. Nucleic Acids Res 25:28-30.
42. Minvielle-Sebastia L, Preker PJ, Keller W. 1994. RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3′-end processing factor. Science 266:1702-1705.
43. Minvielle-Sebastia L, Preker PJ, Wiederkehr T, Strahm Y, Keller W. 1997. The major yeast poly(A)-binding protein is associated with cleavage factor IA and functions in premessenger RNA 3′-end formation. Proc Natl Acad Sci USA 94:7897-7902.
44. Minvielle-Sebastia L, Windsor B, Bonneaud N, Lacroute F. 1991. Mutations in the yeast RNA14 and RNA15 genes result in an abnormal mRNA decay rate; sequence analysis reveals an RNA-binding domain in the RNA15 protein. Mol Cell Biol 11:3075-3087.
45. Mitchell P, Petfalski E, Tollervey D. 1996. The 3′ end of yeast 5.8S rRNA is generated by an exonuclease processing mechanism. Genes & Dev 10:502-513.
46. Morrissey JP, Tollervey D. 1993. Yeast snR30 is a small nucleolar RNA required for 18S rRNA synthesis. Mol Cell Biol 13:2469-2477.
47. Nakai K, Kanehisa M. 1992. A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics 14:897-911.
48. Palmer E, Wilhelm JM, Sherman F. 1979. Phenotypic suppression of nonsense mutants in yeast by aminoglycosidic antibiotics. Nature 277:148-150.
49. Pearson WR, Lipman DJ. 1988. Improved tools for biological sequence comparison. Proc Natl Acad Sci USA 85:2444-2448.
50. Preker PJ, Lingner J, Minvielle-Sebastia L, Keller W. 1995. The FIP1 gene encodes a component of a yeast pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase. Cell 81:379-389.
51. Preker PJ, Ohnacker M, Minvielle-Sebastia L, Keller W. 1997. A multi-subunit 3′ end processing factor from yeast containing poly(A) polymerase and homologues of the subunits of mammalian cleavage and polyadenylation specificity factor. EMBO J 16:4727-4737.
52. - mRNA during translation initiation in Saccharomyces cerevisiae. J Biol Chem 272:6004-6010.
53. Sachs AB, Davis RW. 1989. The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation. Cell 58:857-867.
54. Sachs AB, Sarnow P, Hentze MW. 1997. Starting at the beginning, middle, and end: Translation initiation in eukaryotes. Cell 89:831-838.
55. Sachs A, Wahle E. 1993. Poly(A) tail metabolism and function in eucaryotes. J Biol Chem 268:22955-22958.
56. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
57. Schimmang T, Tollervey D, Kern H, Frank R, Hurt EC. 1989. A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability. EMBO J 8:4015-4024.
58. Singh A, Ursic D, Davies J. 1979. Phenotypic suppression and misreading in Saccharomyces cerevisiae. Nature 277:146-148.
59. Smith V, Chou KN, Lashkari D, Botstein D, Brown PO. 1996. Functional analysis of the genes of yeast chromosome V by genetic footprinting. Science 274:2069-2074.
60. Studier FW. 1991. Use of bacteriophage T7 lysozyme to improve an inducible T7 expression system. J Mol Biol 219:37-44.
61. Tarun SZ, Sachs AB. 1995. A common function for mRNA 5′ and 3′ ends in translation initiation in yeast. Genes & Dev 9:2997-3007.
62. Tarun SZ, Sachs AB. 1996. Association of the yeast poly(A) tail binding protein with translation initiation factor elF-4G. EMBO J 15:7168-7177.
63. Tarun SZ, Wells SE, Deardorff JA, Sachs AB. 1997. Translation initiation factor elF4G mediates in vitro poly(A) tail-dependent translation. Proc Natl Acad Sci USA 94:9046-9051.
64. Tollervey D. 1987. A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA. EMBO J 6:4169-4175.
65. Varshavsky A. 1996. The N-end rule: Functions, mysteries, uses. Proc Natl Acad Sci USA 93:12142-12149.
66. Venema J, Tollervey D. 1995. Processing of pre-ribosomal RNA in Saccharomyces cerevisiae. Yeast 11:1629-1650.
67. Venema J, Tollervey D. 1996. RRP5 is required for formation of both 18S and 5.8S rRNA in yeast. EMBO J 15:5701-5714.
68. Wahle E, Keller W. 1996. The biochemistry of polyadenylation. Trends Biochem Sci 21:247-250.
69. Wilson R, Ainscough R, Anderson K, Baynes C, Berks M, Bonfield J, Burton J, Connell M, Copsey T, Cooper J, Coulson A, Craxton M, Dear S, Du Z, Durbin R, Favello A, Fulton L, Gardner A, Green P, Hawkins T, Hillier L, Jier M, Johnston L, Jones M, Kershaw J, Kirsten J, Laister N, Latreille P, Lightning J, Lloyd C, McMurray A, Mortimore B, O'Callaghan M, Parsons J, Percy C, Rifken L, Roopra A, Saunders D, Shownkeen R, Smaldon N, Smith A, Sonnhammer E, Staden R, Sulston J, Thierry-Mieg J, Thomas K, Vaudin M, Vaughan K, Waterston R, Watson A, Weinstock L, Wilkinson-Sproat J, Wohldman P. 1994. 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature 368:32-38.
70. Zhao J, Kessler MM, Moore CL. 1997. Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian cleavage/polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA. J Biol Chem 272:10831-10838.