A Novel Antioxidant, EPC-K1, Stimulates Endothelial Nitric Oxide Production and Scavenges Hydroxyl Radicals

Circulation Journal

Volumn 67, Issue 12, 2003, Pages 1046-1052

  Takayama, Hiroo ^b   Hamner, Chad E ^a   Caccitolo, James A ^a   Hisamochi, Kunikazu ^a   Pearson, Paul J ^a   Schaff, Hartzell V ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Endothelium; Free radicals; Ischemia; Nitric oxide; Reperfusion

Indexed keywords

ACETYLCHOLINE; ANTIOXIDANT; ARGININE; ASCORBIC ACID; ASCORBIC ACID 2 [3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2 (4,8,12 TRIMETHYLTRIDECYL) 2H 1 BENZOPYRAN 6 YL HYDROGEN PHOSPHATE] POTASSIUM; DEXTRO ARGININE; FREE RADICAL; HYDROXYL RADICAL; INDOMETACIN; N(G) METHYLARGININE; NITRIC OXIDE; PROSTAGLANDIN F2 ALPHA; SUPEROXIDE DISMUTASE; TETRYLAMMONIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY DISEASE; DOG; DRUG EFFECT; FEMALE; ISCHEMIC HEART DISEASE; MALE; NONHUMAN; REPERFUSION INJURY; VASCULAR ENDOTHELIUM;

ANIMALS; ANTIOXIDANTS; ARGININE; ASCORBIC ACID; CORONARY VESSELS; DINOPROST; DOGS; ENDOTHELIUM, VASCULAR; FEMALE; FREE RADICAL SCAVENGERS; HYDROXYL RADICAL; MALE; MODELS, ANIMAL; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; OMEGA-N-METHYLARGININE; VASODILATION; VITAMIN E;

EID: 0344738766     PISSN: 13469843     EISSN: None     Source Type: Journal    
DOI: 10.1253/circj.67.1046     Document Type: Article

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