Estrogen and NMDA receptor antagonism: Effects upon reference and working memory

European Journal of Pharmacology

Volumn 381, Issue 2-3, 1999, Pages 93-99

  Wilson, Iain A ^a   Puoliväli, Jukka ^a   Heikkinen, Taneli ^a   Riekkinen Jr , Paavo ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Estrogen; NMDA receptor antagonism; Ovariectomy; Spatial reference memory; Spatial working memory

Indexed keywords

4 (3 PHOSPHONOPROPYL) 2 PIPERAZINECARBOXYLIC ACID; ESTROGEN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; ESTROGEN ACTIVITY; FEMALE; HIPPOCAMPUS; HORMONAL REGULATION; MAZE TEST; MOUSE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; SPATIAL MEMORY; TASK PERFORMANCE; WORKING MEMORY;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGENS; EXCITATORY AMINO ACID ANTAGONISTS; FEMALE; HIPPOCAMPUS; MAZE LEARNING; MEMORY; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; OVARIECTOMY; PIPERAZINES; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES;

EID: 0344631082     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00583-X     Document Type: Article

References (41)

1. Asthana S., Craft S., Baker L.D., Raskind M.A., Avery E., Lofgren C., Wilkinson C.W., Falzgraf S., Veith S.R., Plymate S.R. Transdermal estrogen improves memory in women with Alzheimer's Disease. Soc. Neurosci. Abstr. 22:1996.
2. Birge S.J. The role of estrogen in the treatment of Alzheimer's disease. Neurology. 48:1997;S36-S41.
3. Bliss T.V., Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature. 361:1993;31-39.
4. Caramanos Z., Shapiro M.L. Spatial memory and N-methyl-D-aspartate receptor antagonists APV and MK-801: memory impairments depend on familiarity with the environment, drug dose, and training duration. Behav. Neurosci. 108:1994;30-43.
5. Cole B.J., Klewer M., Jones G.H., Stephens D.N. Contrasting effects of the competitive NMDA antagonist CPP and the non-competitive NMDA antagonist MK-801 on performance of an operant delayed matching to position task in rats. Psychopharmacology (Berlin). 111:1993;465-471.
6. Crusio W.E., Schwegler H., Lipp H.P. Radial-maze performance and structural variation of the hippocampus in mice: a correlation with mossy fibre distribution. Brain Res. 425:1987;182-185.
7. Daniel J.M., Fader A.J., Spencer A.L., Dohanich G.P. Estrogen enhances performances of female rats during acquisition of a radial arm maze. Horm. Behav. 32:1997;217-225.
8. Gazzaley A.H., Weiland N.G., McEwen B.S., Morrison J.H. Differential regulation of NMDAR1 mRNA and protein by estradiol in the rat hippocampus. J. Neurosci. 16:1996;6830-6838.
9. Gibbs R.B. Effects of estrogen on basal forebrain cholinergic neurons vary as a function of dose and duration of treatment. Brain Res. 757:1997;10-16.
10. Gibbs R.B. Impairment of basal forebrain cholinergic neurons associated with aging and long-term loss of ovarian function. Exp. Neurol. 151:1998;289-302.
11. Gibbs R.B., Aggarwal P. Estrogen and basal forebrain cholinergic neurons: implications for brain aging and Alzheimer's disease related cognitive decline. Horm. Behav. 34:1998;98-111.
12. Gould E., Woolley C.S., Frankfurt M., McEwen B.S. Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood. J. Neurosci. 10:1990;1286-1291.
13. Hampson E. Estrogen-related variations in human spatial and articulatory-motor skills. Psychoneuroendocrinology. 15:1990;97-111.
14. Hampson E., Kimura D. Reciprocal effects of hormonal fluctuations on human motor and perceptual-spatial skills. Behav. Neurosci. 102:1988;456-459.
15. Kampen D.L., Sherwin B.B. Estrogen use and verbal memory in healthy postmenopausal women. Obstet. Gynecol. 83:1994;979-983.
16. Lyford G.L., Jarrard L.E. Effects of the competitive NMDA antagonist CPP on performance of a place and cue radial arm maze task. Psychobiology. 19:1991;157-160.
17. Morris R.G., Anderson E., Lynch G.S., Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature. 319:1986;774-776.
18. Murphy D.D., Segal M. Regulation of dendritic spine density in cultured rat hippocampal neurons by steroid hormones. J. Neurosci. 16:1996;4059-4068.
19. Olton D.S., Walker J.A., Gage F.H. Hippocampal connections and spatial discrimination. Brain Res. 139:1978;295-308.
20. O'Malley C., Hautamaki R.D., Kelley M., Meyer E.M. Effects of ovariectomy and estradiol benzoate on high affinity choline uptake, ACh synthesis, and release from rat cerebral cortical synaptosomes. Brain Res. 403:1987;389-392.
21. O'Neal M., Means L.W., Poole M.C., Hamm R.J. Estrogen affects performance of ovariectomized rats in a two-choice water-escape working memory task. Psychoneuroendocrinology. 21:1996;51-65.
22. Packard M.G., Teather L.A. Posttraining estradiol injections enhance memory in ovariectomized rats: cholinergic blockade and synergism. Neurobiol. Learn. Mem. 68:1997;172-188.
23. Paganini-Hill A., Henderson V.W. Estrogen deficiency and risk of Alzheimer's disease in women. Am. J. Epidemiol. 140:1994;256-261.
24. Phillips S.M., Sherwin B.B. Effects of estrogen on memory function in surgically menopausal women. Psychoneuroendocrinology. 17:1992;485-495.
25. Pontecorvo M.J., Clissold D.B., White M.F., Ferkany J.W. N-methyl-D-aspartate antagonists and working memory performance: comparison with the effects of scopolamine, propranolol, diazepam, and phenylisopropyladenosine. Behav. Neurosci. 105:1991;521-535.
26. Riekkinen M., Riekkinen P. Jr. Dorsal hippocampal muscarinic acetylcholine and NMDA receptors disrupt water maze navigation. NeuroReport. 8:1997;645-648.
27. Riekkinen M., Stefanski R., Kuitunen J., Riekkinen P. Jr. Effects of combined block of alpha 1-adrenoceptors and NMDA receptors on spatial and passive avoidance behavior in rats. Eur. J. Pharmacol. 300:1996;9-16.
28. Schneider L.S., Finch C.E. Can estrogens prevent neurodegeneration? Drugs Aging. 11:1997;87-95.
29. Shen J., Barnes C.A., Wenk G.L., McNaughton B.L. Differential effects of selective immunotoxic lesions of medial septal cholinergic cells on spatial working and reference memory. Behav. Neurosci. 110:1996;1181-1186.
30. Sherwin B.B. Estrogenic effects on memory in women. Ann. N. Y. Acad. Sci. 743:1994;213-230. discussion 230-211.
31. Sherwin B.B. Estrogen effects on cognition in menopausal women. Neurology. 48:1997;S21-S26.
32. Simpkins J.W., Green P.S., Gridley K.E., Singh M., de Fiebre N.C., Rajakumar G. Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease. Am. J. Med. 103:1997;19s-25s.
33. Singh M., Meyer E.M., Millard W.J., Simpkins J.W. Ovarian steroid deprivation results in a reversible learning impairment and compromised cholinergic function in female Sprague-Dawley rats. Brain Res. 644:1994;305-312.
34. Walsh T.J., Herzog C.D., Gandhi C., Stackman R.W., Wiley R.G. Injection of IgG 192-saporin into the medial septum produces cholinergic hypofunction and dose-dependent working memory deficits. Brain Res. 726:1996;69-79.
35. Ward L., Mason S.E., Abraham W.C. Effects of the NMDA antagonists CPP and MK-801 on radial arm maze performance in rats. Pharmacol. Biochem. Behav. 35:1990;785-790.
36. Weiland N.G. Estradiol selectively regulates agonist binding sites on the N-methyl-D-aspartate receptor complex in the CA1 region of the hippocampus. Endocrinology. 131:1992;662-668.
37. Woolley C.S., McEwen B.S. Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat. J. Neurosci. 12:1992;2549-2554. [published erratum appears in J. Neurosci. 1992 Oct; 12(10): following table of contents].
38. Woolley C.S., McEwen B.S. Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat. J. Comp. Neurol. 336:1993;293-306.
39. Woolley C.S., McEwen B.S. Estradiol regulates hippocampal dendritic spine density via an N-methyl-D-aspartate receptor-dependent mechanism. J. Neurosci. 14:1994;7680-7687.
40. Woolley C.S., Gould E., Frankfurt M., McEwen B.S. Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons. J. Neurosci. 10:1990;4035-4039.
41. Woolley C.S., Weiland N.G., McEwen B.S., Schwartzkroin P.A. Estradiol increases the sensitivity of hippocampal CA1 pyramidal cells to NMDA receptor-mediated synaptic input: correlation with dendritic spine density. J. Neurosci. 17:1997;1848-1859.