Synthesis of NCA [carbonyl-11C]amides by direct reaction of in situ generated [11C]carboxymagnesium halides with amines under microwave-enhanced conditions

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 46, Issue 13, 2003, Pages 1249-1259

  Lu, Shui Yu ^a   Hong, Jinsoo ^a   Pike, Victor W ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Amide; Carbon 11; Grignard reagent; Microwave; 11C carbon dioxide

Indexed keywords

AMIDES; AMINES; CHLORINE COMPOUNDS;

CARBON-11; CONDITION; DIRECT REACTIONS; GRIGNARD REAGENT; ONE POT; PRIMARY AMINES; RADIOCHEMICAL YIELD; SYNTHESISED; [11C]CARBON DIOXIDE; [CARBONYL;

CARBON DIOXIDE;

2 (METHYLAMINO)PYRIDINE; 4 FLUOROPHENYLCARBOXYMAGNESIUM BROMIDE; AMIDE; AMINE; AMINOPYRIDINE DERIVATIVE; ANILINE DERIVATIVE; CARBON 11; CARBON DIOXIDE; CARBOXYMAGNESIUM HALIDE C 11; CYCLOHEXYLCARBOXYMAGNESIUM CHLORIDE; HALIDE; PYRIDINE DERIVATIVE; REAGENT; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CYCLOTRON; MICROWAVE RADIATION; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; SYNTHESIS; TEMPERATURE DEPENDENCE;

EID: 0344551275     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlcr.786     Document Type: Article

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