Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes

Toxicology in Vitro

Volumn 18, Issue 1, 2004, Pages 63-70

  Coyle, Barry ^a   Kinsella, Paula ^b   McCann, Malachy ^a   Devereux, Michael ^c   O'Connor, Robert ^b   Clynes, Martin ^b   Kavanagh, Kevin ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b DUBLIN CITY UNIVERSITY   (Ireland)

^c DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

Author keywords

Apoptosis; Candida; Fungicidal; Fungistatic; Metal based drug

Indexed keywords

1,10 PHENANTHROLINE; CELL DNA; DNA FRAGMENT; MALONIC ACID; METAL COMPLEX;

APOPTOSIS; ARTICLE; CANDIDA ALBICANS; CELL MEMBRANE; CELL ORGANELLE; CELL STRUCTURE; CONTROLLED STUDY; CYTOPLASM; DNA DEGRADATION; ELECTROPHORESIS; EVIDENCE BASED MEDICINE; EXPOSURE; HUMAN; HUMAN CELL; MAMMAL CELL; YEAST; YEAST CELL;

CANDIDA; CANDIDA ALBICANS; MAMMALIA;

EID: 0344549617     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2003.08.011     Document Type: Article

References (31)

1. Abu-Salah K.M. Amphotericin B. an update British Journal of Biomedical Science. 53:1996;122-133.
2. Butler H.M., Hurse A., Thursky E., Shulman A. Bactericidal action of selected phenanthroline chelates and related compounds. Australian Journal of Experimental Biological and Medical Science. 47:1969;541-552.
3. Chen C.H., Sigman D.S. Nuclease activity of 1,10 phenanthroline-copper: sequence specific targeting. Proceedings of the National Academy of Science. 83:1986;7147-7151.
4. Cohen J.J. Overview. mechanisms of apoptosis Immunology Today. 14:1993;126-130.
5. Cotter T.G., Al-Rubeai M. Cell death (apoptosis) in cell culture systems. Trends in Biotechnology. 13:1995;150-155.
6. Coyle B., Kavanagh K., McCann M., Devereux M., Geraghty M. Mode of anti-fungal activity of 1,10-phenanthroline and its Cu(II), Mn(II) and Ag(I) complexes. BioMetals. 16:2003;321-329.
7. De Pauw B.E. Practical modalities for prevention of fungal infections in cancer patients. European Journal of Clinical Microbiology and Infectious Disease. 16:1997;32-41.
8. De Vizcaya-Ruiz A., Riverro-Muller A., Ruiz-Ramirez L., Kass G.N., Kelland L.R., Orr R.M., Dobrota M. Induction of apoptosis by a novel copper-based anticancer compound, Casiopenia II, in L1210 murine leukaemia and CH1 human ovarian carcinoma cell. Toxicology in Vitro. 14:2000;1-5.
9. 2=fumaric acid; bipy=2,2′-bipyridine; phen=1,10-phenanthroline) . Polyhedron. 19:2000;1205-1211.
10. 2= phthalic acid; Isoph=isophthalic acid; Phen=1,10- phenanthroline; bipy=2,2-bipyridine). Metal-Based Drugs. 7:2000;275-288.
11. Dwyer F.P., Reid I.K., Shulman A., Laycock G.M., Dixon S. The biological actions of 1,10-phenanthroline and 2,2′-bipyridine hydrochlorides, quaternary salts and metal chelates and related compounds. 1. Bacteriostatic action on selected gram-positive, gram-negative and acid-fast bacteria. Australian Journal of Experimental and Biological Medical Science. 47:1969;203-218.
12. Feeney R.E., Petersen I.M., Sahinkaya H. "Liesegang-like" rings of growth and inhibition of bacteria in agar caused by metal ions and chelating agents. Journal of Bacteriology. 73:1957;284-290.
13. 2O (phen=1,10-phenanthroline). Metal-Based Drugs. 6:1999;41-48.
14. 2=cis-5- norbornene-endo-2,3-dicarboxylic acid; bipy =2,2′-bipyridine; phen=1,10-phenanthroline). Polyhedron. 18:1999;2931-2939.
15. 2O (phen=1,10-phenanthroline). Inorganic Chimica Acta. 293:1999;160-166.
16. Geraghty M., Cronin J.F., Devereux M., McCann M. Synthesis and anti-microbial activity of copper(II) and manganese(II) α,ω- dicarboxylate complexes. BioMetals. 13:2000;1-8.
17. 2=cis-5-norbornene-endo-2,3-dicarboxylic acid; bipy=2,2′-bipyridine; phen=1,10-phenanthroline). Polyhedron. 18:1998;2931-2939.
18. Green D., Kroemer G. The central executioners of apoptosis. caspases or mitochondria? Trends in Cell Biology. 8:1998;267-271.
19. Jessee B., Gargiulo G., Razvi F., Worcel A. Analogous cleavage of DNA by micrococcal nuclease and a 1,10-phenanthroline-cuprous complex. Nucleic Acid Research. 10:1982;5823-5833.
20. Lunel F.M., Meis F.G., Voss A. Nosocomial fungal infections. Candidemia Diagnostic Microbiology and Infectious Diseases. 34:1999;213-220.
21. Kontoyiannis D.P., Lewis R.E. Antifungal drug resistance in pathogenic fungi. Lancet. 359:2002;1135-1143.
22. Martin A., Clynes M. Comparison of 5 microtitre colormetric assays for in vitro cytotoxicity testing and cell proliferation assays. Cytotechnology. 11:1993;49-58.
23. McCann M., Geraghty M., Devereux M., O'Shea D., Mason J., O'Sullivan L. Insights into the mode of action of the anti-Candida activity of 1,10-phenanthroline and its metal chelates. Metal-Based Drugs. 7:2000;185-193.
24. MacLeod R.A. The toxicity of o-phenanthroline for lactic acid bacteria. Journal of Biological Chemistry. 197:1952;751-761.
25. Nobel C., Kimland M., Lind B., Orrenius S., Slater A.F. Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper. Journal of Biological Chemistry. 270:1995;26202-26208.
26. Pfaller M.A., Jones R.N., Messer S.A., Edmond M.B., Wenzel R.P. National surveillance of nosocomial blood stream infection due to Candida albicans. frequency of occurrence and anti-fungal susceptibility in the SCOPE programme Diagnostic Microbial Infectious Disease. 31:1998;327-332.
27. Roze L.V., Linz J.E. Lovastatin triggers an apoptosis-like death process in the fungus Mucor recemosus. Fungal Genetics Biology. 25:1998;119-133.
28. Van den Bossche H., Dromer F., Improvissi I., Lozane-Chiu M., Rex J.H., Sanglard D. Anti-fungal drug resistance in pathogenic fungi. Medical Mycology. 36(Supp. 1):1998;119-128.
29. Verhaegen S. Microscopical study of cell death via apoptosis. Microscopy Analysis. 1:1998;5-7.
30. Zhou H., Zheng C., Zou G., Tao D., Gong J. G1-phase specific apoptosis in liver carcinoma cell line induced by copper-1,10-phenanthroline. International Journal of Biochemistry and Cell Biology. 34:2002;678-684.
31. Zhou H., Liu Y., Zheng C., Gong J., Liang Y., Wang C., Zou G. Microcalorimetric studies of the synergistic effects of copper-1,10- phenanthroline combined with hyperthermia on a liver hepatoma cell line Bel-7402. Thermochimica Acta. 7149:2002;1-9.