Site specific predictors of positive margins at radical prostatectomy: An argument for risk based modification of technique

Journal of Urology

Volumn 160, Issue 5, 1998, Pages 1727-1733

  Rabbani, Farhang ^a   Bastar, Andrew ^a   Fair, William R ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Multivariate analysis; Prostatectomy; Prostatic neoplasms

Indexed keywords

ANDROGEN; PROSTATE SPECIFIC ANTIGEN;

ADJUVANT CHEMOTHERAPY; ADULT; ARTICLE; BLADDER OBSTRUCTION; CANCER LOCALIZATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSTATE BIOPSY; PROSTATECTOMY; REGRESSION ANALYSIS; SURGICAL TECHNIQUE;

EID: 0344549180     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)62394-2     Document Type: Article

References (35)

1. Walsh, P. C.: Radical retropubic prostatectomy. In: Campbell's Urology, 6th ed. Edited by P. C. Walsh, A. B. Retik, T. A. Stamey and E. D. Vaughan, Jr. Philadelphia: W. B. Saunders Co., vol. 3, chapt. 78, pp. 2865-2886, 1992.
2. Quinlan, D. M., Epstein, J. I., Carter, B. S. and Walsh, P. C.: Sexual function following radical prostatectomy: influence of preservation of neurovascular bundles. J. Urol., 145: 998, 1991.
3. Licht, M. R., Klein, E. A., Tuason, L. and Levin, H.: Impact of bladder neck preservation during radical prostatectomy on continence and cancer control. Urology, 44: 883, 1994.
4. Braslis, K. G., Petsch, M., Lim, A., Civantos, F. and Soloway, M. S.: Bladder neck preservation following radical prostatectomy: continence and margins. Eur. Urol., 28: 202, 1995.
5. Gomez, C. A., Soloway, M. S., Civantos, F. and Hachiya, T.: Bladder neck preservation and its impact on positive surgical margins during radical prostatectomy. Urology, 42: 689, 1993.
6. Lowe, B. A.: Comparison of bladder neck preservation to bladder neck resection in maintaining postprostatectomy urinary continence. Urology, 48: 889, 1996.
7. Gaker, D. L., Gaker, L. B., Stewart, J. F. and Gillenwater, J. Y.: Radical prostatectomy with preservation of urinary continence. J. Urol., 156: 445, 1996.
8. Epstein, J. I., Partin, A. W., Sauvageot, J. and Walsh, P. C.: Prediction of progression following radical prostatectomy. A multivariate analysis of 721 men with long-term follow-up. Amer. J. Surg. Path., 20: 286, 1996.
9. D'Amico, A. V., Whittington, R., Malkowicz, B., Schultz, D., Schnall, M., Tomaszewski, J. E. and Wein, A.: A multivariate analysis of clinical and pathological factors that predict for prostate specific antigen failure after radical prostatectomy for prostate cancer. J. Urol., 154: 131, 1995.
10. Van den Ouden, D., Bentvelsen, F. M., Boevé, E. R. and Schröder, F. H.: Positive margins after radical prostatectomy: correlation with local recurrence and distant progression. Brit. J. Urol., 72: 489, 1993.
11. Epstein, J. I.: Incidence and significance of positive margins in radical prostatectomy specimens. Urol. Clin. N. Amer., 23: 651, 1996.
12. Stamey, T. A., Villers, A. A., McNeal, J. E., Link, P. C. and Freiha, F. S.: Positive surgical margins at radical prostatectomy: importance of the apical dissection. J. Urol., 143: 1166, 1990.
13. Ackerman, D. A., Barry, J. M., Wicklund, R. A., Olson, N. and Lowe, B. A.: Analysis of risk factors associated with prostate cancer extension to the surgical margin and pelvic node metastasis at radical prostatectomy. J. Urol., 150: 1845, 1993.
14. Rabbani, F., Sullivan, L. D., Goldenberg, S. L. and Stothers, L.: Neoadjuvant androgen deprivation therapy before radical prostatectomy: who is unlikely to benefit? Brit. J. Urol., 79: 221, 1997.
15. Beahrs, O. H., Henson, D. E., Hutter, R. V. P. and Kennedy, B. J.: Handbook for Staging of Cancer. Philadelphia: J. B. Lippincott, chapt. 31, pp. 189-193, 1993.
16. Blute, M. L., Bostwick, D. G., Bergstralh, E. J., Slezak, J. M., Martin, S. K., Amling, C. L. and Zincke, H.: Anatomic site-specific positive margins in organ-confined prostate cancer and its impact on outcome after radical prostatectomy. Urology, 50: 733, 1997.
17. Fesseha, T., Sakr, W., Grignon, D., Banerjee, M., Wood, D. P., Jr. and Pontes, J. E.: Prognostic implications of a positive apical margin in radical prostatectomy specimens. J. Urol., 158: 2176, 1997.
18. Weldon, V. E., Tavel, F. R., Neuwirth, H. and Cohen, R.: Patterns of positive specimen margins and detectable prostate specific antigen after radical perineal prostatectomy. J. Urol., 153: 1565, 1995.
19. Soloway, M. S., Sharifi, R., Wajsman, Z., McLeod, D., Wood, D. P., Jr. and Puras-Baez, A. for the Lupron Depot Neoadjuvant Prostate Cancer Study Group.: Randomized prospective study comparing radical prostatectomy alone versus radical prostatectomy preceded by androgen blockade in clinical stage B2 (T2bNxM0) prostate cancer. J. Urol., 154: 424, 1995.
20. Watson, R. B., Civantos, F. and Soloway, M. S.: Positive surgical margins with radical prostatectomy: detailed pathological analysis and prognosis. Urology, 48: 80, 1996.
21. Wood, D. P., Jr., Peretsman, S. J. and Seay, T. M.: Incidence of benign and malignant prostate tissue in biopsies of the bladder neck after a radical prostatectomy. J. Urol., 154: 1443, 1995.
22. Epstein, J. I., Pizov, G. and Walsh, P. C.: Correlation of pathologic findings with progression after radical retropubic prostatectomy. Cancer, 71: 3582, 1993.
23. Alsikafi, N. F. and Brendler, C. B.: Surgical modifications of radical retropubic prostatectomy to decrease incidence of positive surgical margins. J. Urol., 159: 1281, 1998.
24. Catalona, W. J. and Bigg, S. W.: Nerve-sparing radical prostatectomy: evaluation of results after 250 patients. J. Urol., 143: 538, 1990.
25. Rosen, M. A., Goldstone, L., Lapin, S., Wheeler, T. and Scardino, P. T.: Frequency and location of extracapsular extension and positive surgical margins in radical prostatectomy specimens. J. Urol., 148: 331, 1992.
26. Kava, B. R., Stroumbakis, N., Dalbagni, G., Cookson, M., Sogani, P. C., Russo, P., Herr, H., Sheinfeld, J., Reuter, V., Rosai, J., Begg, C. and Fair, W. R.: Prospective randomized clinical trial comparing primary therapy with Zoladex + flutamide and radical prostatectomy versus radical prostatectomy alone in patients with clinically localized prostate cancer. J. Urol., part 2, 157: 253, abstract 990, 1997.
27. Goldenberg, S. L., Klotz, L. H., Srigley, J., Jewett, M. A. S., Mador, D., Fradet, Y., Barkin, J., Chin, J., Faquin, J.-M., Bullock, M. J., LaPlante, S. and Canadian Urologic Oncology Group.: Randomized, prospective, controlled study comparing radical prostatectomy alone and neoadjuvant androgen withdrawal in the treatment of localized prostate cancer. J. Urol., 156: 873, 1996.
28. Van Poppel, H., De Ridder, D., Elgamal, A. A., Van de Voorde, W., Werbrouck, P., Ackaert, K., Oyen, R., Pittomvils, G., Baert, L. and members of the Belgian Uro-Oncological Study Group.: Neoadjuvant hormonal therapy before radical prostatectomy decreases the number of positive surgical margins in stage T2 prostate cancer: interim results of a prospective randomized trial. J. Urol., 154: 429, 1995.
29. Greene, D. R., Wheeler, T. M., Egawa, S., Dunn, J. K. and Scardino, P. T.: A comparison of the morphological features of cancer arising in the transition zone and in the peripheral zone of the prostate. J. Urol., 146: 1069, 1991.
30. Jones, E. C.: Resection margin status in radical retropubic prostatectomy specimens: relationship to type of operation, tumor size, tumor grade and local tumor extension. J. Urol., 144: 89, 1990.
31. Catalona, W. J. and Dresner, S. M.: Nerve-sparing radical prostatectomy: extraprostatic tumor extension and preservation of erectile function. J. Urol., 134: 1149, 1985.
32. Huland, H., Hübner, D. and Henke, R. P.: Systematic biopsies and digital rectal examination to identify the nerve-sparing side for radical prostatectomy without risk of positive margin in patients with clinical stage T2, N0 prostatic carcinoma. Urology, 44: 211, 1994.
33. Goldenberg, S. L., Klotz, L., Jewett, M., Barkin, J., Chetner, M., Fradet, Y., Chin, J. and the Canadian Uro-Oncology Group.: A randomized trial of neoadjuvant androgen withdrawal therapy prior to radical prostatectomy: 24 month post-treatment PSA results. J. Urol., part 2, 157: 92, abstract 357, 1997.
34. Soloway, M., Sharifi, R., Wajsman, Z., McLeod, M., Wood, D., Jr., Puras-Baez, A. and the Lupron Depot Neoadjuvant Study Group: Radical prostatectomy alone vs radical prostatectomy preceded by androgen blockade in cT2b prostate cancer - 24 month results. J. Urol., part 2, 157: 160, abstract 619, 1997.
35. Rabbani, F., Goldenberg, S. L., Klotz, L. H. and the Canadian Urologic Oncology Group: Predictors of pathologic stage before neoadjuvant androgen withdrawal therapy and radical prostatectomy. J. Urol., 159: 925, 1998.