The contractile response of the mesenteric resistance arteries to prostaglandin F2α; effects of simultaneous hyperlipemia- diabetes

Fundamental and Clinical Pharmacology

Volumn 17, Issue 6, 2003, Pages 683-689

  Georgescu, Adriana ^a   Popov, Doina ^a  

^a INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY NICOLAE SIMIONESCU   (Romania)

Author keywords

Diabetes; Hyperlipemia; Mesenteric resistance arteries; Prostaglandin f 2

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; CHOLESTEROL; GLUCOSE; INDOMETACIN; PHORBOL 13 ACETATE 12 MYRISTATE; POTASSIUM CHANNEL BLOCKING AGENT; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; TETRYLAMMONIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVATION; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; HAMSTER; HYPERGLYCEMIA; HYPERLIPIDEMIA; MALE; MESENTERIC ARTERY; MUSCLE FORCE; MUSCLE ISOMETRIC CONTRACTION; MYOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RESISTANCE BLOOD VESSEL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY;

AGING; ANIMALS; BLOOD GLUCOSE; CRICETINAE; DIABETES MELLITUS, EXPERIMENTAL; DINOPROST; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYPERLIPIDEMIAS; INDOMETHACIN; MALE; MESENTERIC ARTERIES; MESOCRICETUS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; PROTEIN KINASE C; TETRAETHYLAMMONIUM; TIME FACTORS; VASOCONSTRICTION;

EID: 0344513995     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1472-8206.2003.00196.x     Document Type: Article

References (33)

1. Perez-Martinez S., Franchi A.M., Viggiano J.M., Herrero M.B., Gimeno M. Effect of prostaglandin F2 alpha (PGF2alpha) on oviductal nitric oxide synthase (NOS) activity: possible role of endogenous NO on PGF2 alpha-induced contractions in rat oviduct. Prostaglandins other Lipid. Mediat. (1998) 56 155-166.
2. Al-Matubsi H.Y., Eis A.L., Brodt-Eppley J., MacPhee D.J., Lye S., Myatt T. Expression and localization of the contractile prostaglandin F receptor in pregnant rat myometrium in late gestation, labor, and postpartum. Biol. Reprod. (2001) 65 1029-1037.
3. Park S.J., Nakashima M., Nagao T., Vanhoutte P.M. Hyperpolarization caused by serotonin contributes to endothelium-dependent relaxations in the porcine coronary artery. Zhongguo Yao Li Xue Bao (1999) 20 1093-1097.
4. Ray E.C., Landis M.E., Miller V.M. Effects of dietary L-arginine on the reactivity of canine coronary arteries. Vasc. Med. (1999) 4 211-217.
5. Komuro T., Borsody M.K., Ono S. et al. The vasorelaxation of cerebral arteries by carbon monoxide. Exp. Biol. Med. (2001) 226 860-865.
6. Chen S., Wu C.C., Yen M.H. Exercise training activates large-conductance calcium-activated K(+) channels and enhances nitric oxide production in rat mesenteric artery and thoracic aorta. J. Biomed. Sci. (2001) 8 248-255.
7. Jones R.D., Morice A.H. The effect of the nitric oxide synthase inhibitor N-gamma-nitro-L-arginine methyl ester on hypoxic pulmonary vasoconstriction. Eur. J. Pharmacol. (2000) 402 111-117.
8. Okatani Y., Wakatsuki A., Watanabe K., Taniguchi K., Fukaya T. Weak vasoconstrictor activity of melatonin in human umbilical artery: relation to nitric oxide-scavenging action. Eur. J. Pharmacol. (2001) 417 125-129.
9. Delaey C. Retinal tissue modulates retinal arterial tone through the release of a potent vasodilating factor. Verh K Acad. Geneeskd. Belg. (2001) 63 335-357.
10. 2α-responses is inhibited by hipoxygenase-but not cyclooxygenase inhibitors in mesenteric veins and arteries of mouse and rat. Jpn. J. Pharmacol. (1994) 64 60-65.
11. Hata Y., Pancho L.R., Nojima H., Kimura I., Endothelium-dependent potentiation of prostaglandin F2alpha-induced contractions by (±)-[6]-gingerol is inhibited by cyclooxygenase - but not lipoxygenase-inhibitors in mouse mesenteric veins. Biol. Pharm. Bull. (1998) 21 792-794.
12. Michoud E., Lecomte M., Lagarde M., Wiernsperger N. In vivo effect of 8-epi-PGF2alpha on retinal circulation in diabetic and non-diabetic rats. Prostaglandins Leukot. Essent. Fatty Acids. (1998) 59 349-355.
13. Wentzel P., Welsh N., Eriksson U.J. Developmental damage, increased lipid peroxidation, diminished cyclooxygenase-2 gene expression, and lowered prostaglandin E2 levels in rat embryos exposed to a diabetic environment. Diabetes (1999) 48 813-820.
14. Oguogho A., Mehrabi M., Sinzinger H. Increased plasma, serum and urinary 8-epi-prostaglandin F2alpha in heterozygous hypercholesterolemia. Wien Klin Wochenschr (1999) 111 113-118.
15. Oguogho A., Kritz H., Wagner O., Sinzinger H. 6-oxo-PGF (1 alpha) and 8-epi-PGF (2 alpha) in the arterial wall layers of various species: a comparison between intact and atherosclerosis areas. Prostaglandins Leukot. Essent. Fatty Acids. (2001) 64 167-171.
16. Simionescu M., Popov D., Sima A. et al. Pathobiochemistry of combined diabetes and atherosclerosis studied an a novel animal model. The hyperlipemic-hyperglycemic hamster. Am. J. Pathol. (1996) 148 997-1014.
17. Mulvany M., Halpern W. Contractile properties of small arteriolar resistance vessels in spontaneously hypertensive and normotensive rats. Circ. Res. (1977) 41 19-26.
18. Chulia T., Gonzales P., Del Rio M., Tejerina T. Comparative study of elgodipine and nisoldipine an the contractile responses of various isolated blood vessels. Eur. J. Pharmacol. (1995) 285 115-122.
19. Mulvany M.J., Aalkjer C. Structure and function of small arteries. Physiol. Rew. (1990) 70 921-961.
20. Ohtani H. Effects of dietary cholesterol and fatty acids on plasma cholesterol and hepatic lipoprotein metabolism. J. Lipid Res. (1990) 31 1413-1422.
21. Sullivan M.P., Cerda J.J., Robbins F.L., Burgin C.W., Beatty R.J. The gerbil, hamster and guinea pig as rodent models for hyperlipidemia. Lab. Anim. Sci. (1993) 43 575-578.
22. Nistor A., Bulla A.A., Filip D.A., Radu A. The hyperlipidemic hamster as a model of experimental atherosclerosis. Atherosclerosis (1987) 68 159-173.
23. Lithell H., Berne C. In: Pharmacology of Diabetes: present practice and future perspectives. Mogensen C.E., Standl E. (Eds). Walter de Gruyter 1991, pp. 57-74.
24. Popov D., Simionescu M. Alterations of lung structure in experimental diabetes, and diabetes associated with hyperlipidaemia in hamsters. Eur. Respir. J. (1997) 10 1850-1858.
25. Costache G., Popov D., Georgescu A., Cenuse M., Jinga V.V., Simionescu M. The effect of simultaneous hyperlipemia-hyperglycemia on the mesenteric resistance arteries, myocardium and kidney glomeruli. J. Submicroscop. Cytol. Pathol. (2000) 32 47-58.
26. + channels. Fund. Clin. Pharmacol. (2001) 15 335-342.
27. Georgescu A., Popov D. AGE-dependent accumulation of advanced glycation endproducts is accelerated in combined hyperlipidemia and hyperglycemia, a process attenuated by L-arginine. J. Amer. Aging Assoc. (2000) 23 33-40.
28. Popov D., Costache G., Georgescu A., Enache M. Beneficial effects of L-arginine supplementation in experimental hyperlipemia - hyperglycemia in the hamster. Cell Tissue Res. (2002) 308 109-120.
29. Georgescu A., Popov D. Vascular reactivity of the resistance arteries to potassium in combined hyperlipemia-hyperglycemia. Proc. Rom. Acad. Series B (2001) 2 111-115.
30. Sirikci O., Ozer N.K., Azzi A. Dietary cholesterol-induced changes of protein kinase C and the effect of vitamin E in rabbit aortic smooth muscle cells. Atheriosclerosis (1996) 126 253-263.
31. 2. Am. J. Physiol. (1989) 257 H1327-H1333.
32. Cox R.H., Rusch N.J. New expression profiles of voltage-gated ion channels in arteries exposed to high blood pressure. Microcirculation. (2002) 9 243-257.
33. Griffin B.W., Magnino P.E., Pang I.H., Sharif N.A. Pharmacological characterization of an FP prostaglandin receptor on rat vascular smooth muscle cells (A7r5) coupled to phosphoinositide turnover and intracellular calcium mobilization. J. Pharmacol. Exp. Ther. (1998) 286 411-418.