Identification of genes regulated during osteoblastic differentiation by genome-wide expression analysis of mouse calvaria primary osteoblasts in vitro

Bone

Volumn 32, Issue 5, 2003, Pages 474-482

  Roman Roman, S ^a,d   Garcia, T ^a   Jackson, A ^a   Theilhaber, J ^b   Rawadi, G ^a   Connolly, T ^b   Spinella Jaegle, S ^c   Kawai, S ^a   Courtois, B ^c   Bushnell, S ^b   Auberval, M ^a   Call, K ^b   Baron, R ^a  

^a ProSkelia Pharmaceuticals   (France)

^b Cambridge Genomics Center   (United States)

^c SANOFI   (France)

^d Proskelia Pharmaceuticals   (France)

Author keywords

Calvaria; Gene expression; Osteoblast differentiation; Probe arrays

Indexed keywords

ANIMAL CELL; ARTICLE; CALVARIA; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL MATURATION; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GENOME; MOUSE; MULTIGENE FAMILY; NEWBORN; NONHUMAN; OSTEOBLAST;

EID: 0344438114     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(03)00052-8     Document Type: Article

References (48)

1. Aubin JE, Liu F. The osteoblast lineage. In: Bilezikian JP, Raisz LG, Rodan GA, editors. Principles of bone biology. San Diego, CA: Academic Press; 1996, p. 51-68.
2. Rodan GA, Noda M. Gene expression in osteoblastic cells. Crit Rev Eukaryot Gene Expr 1991;1:85-98.
3. Aubin JE, Liu F, Malaval L, Gupta AK. Osteoblast and chondroblast differentiation. Bone 1995;17:77S-83S.
4. Beck GR Jr, Zerler B, Moran E. Gene array analysis of osteoblast differentiation. Cell Growth Differ 2001;12:61-83.
5. Seth A, Lee BK, Qi S, Vary CP. Coordinate expression of novel genes during osteoblast differentiation. J Bone Miner Res 2000;15: 1683-96.
6. Garcia T, Roman-Roman S, Jackson A, Theilhaber J, Connolly T, Spinella-Jaegle S, Kawai S, Courtois B, Bushnell S, Auberval M, Call K, Baron R. Behavior of osteoblast, adipocyte, and myoblast markers in genome-wide expression analysis of mouse calvaria primary osteoblasts in vitro. Bone 2002;31:205-11.
7. Theilhaber J, Bushnell S, Jackson A, Fuchs R. Bayesian estimation of fold-changes in the analysis of gene expression: the PFOLD algorithm. J Comput Biol 2001;8:585-614.
8. Murray SS, Glackin CA, Winters KA, Gazit D, Kahn AJ, Murray EJ. Expression of helix-loop-helix regulatory genes during differentiation of mouse osteoblastic cells. J Bone Miner Res 1992;7:1131-8.
9. Lee MS, Lowe G, Flanagan S, Kuchler K, Glackin CA. Human Dermo-1 has attributes similar to twist in early bone development. Bone 2000;27:591-602.
10. Mortlock DP, Innis JW. Mutation of HOXA13 in hand-foot-genital syndrome. Nature Genet 1997;15:179-80.
11. Post LC, Innis JW. Infertility in adult hypodactyly mice is associated with hypoplasia of distal reproductive structures. Biol Reprod 1999; 61:1402-8.
12. Towler DA, Rutledge SJ, Rodan GA. Msx-2/Hox 8.1: a transcriptional regulator of the rat osteocalcin promoter. Mol Endocrinol 1994;8:1484-93.
13. Hu Y, Flanagan J, Brennan DP, Zhou H, Ng KW, Eisman JA, Morrison NA. rHox: a homeobox gene expressed in osteoblastic cells. J Cell Biochem 1995;59:486-97.
14. Lu MF, Cheng HT, Kern MJ, Potter SS, Tran B, Diekwisch TG, Martin JF. prx-1 functions cooperatively with another paired-related homeobox gene, prx-2, to maintain cell fates within the craniofacial mesenchyme. Development 1999;126:495-504.
15. Clauss IM, Gravallese EM, Darling JM, Shapiro F, Glimcher MJ, Glimcher LH. In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis. Dev Dyn 1993;197:146-56.
16. Filanti C, Dickson GR, Di Martino D, Ulivi V, Sanguined C, Romano P, Palermo C, Manduca P. The expression of metalloproteinase-2, -9, and -14 and of tissue inhibitors-1 and -2 is developmentally modulated during osteogenesis in vitro, the mature osteoblastic phenotype expressing metalloproteinase-14. J Bone Miner Res 2000;15:2154-68.
17. Uchida M, Shima M, Shimoaka T, Fujieda A, Obara K, Suzuki H, Nagai Y, Ikeda T, Yamato H, Kawaguchi H. Regulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloprotein-ases (TIMPs) by bone resorptive factors in osteoblastic cells. J Cell Physiol 2000;185:207-14.
18. Winchester SK, Selvamurugan N, D'Alonzo RC, Partridge NC. Developmental regulation of collagenase-3 inRNA in normal, differentiating osteoblasts through the activator protein-1 and the runt domain binding sites. J Biol Chem 2000;275:23310-8.
19. Jimenez MJ, Balbin M, Lopez JM, Alvarez J, Komori T, Lopez-Otin C. Collagenase 3 is a target of Cbfal, a transcription factor of the runt gene family involved in bone formation. Mol Cell Biol 1999;19: 4431-42.
20. Kitten AM, Andrews CJ. Endothelin-1 expression in long-term cultures of fetal rat calvarial osteoblasts: regulation by BMP-7. J Cell Physiol 2001;187:218-25.
21. Chapman HA, Riese RJ, Shi GP. Emerging roles for cysteine proteases in human biology. Annu Rev Physiol 1997;59:63-88.
22. Soderstrom M, Salminen H, Glumoff V, Kirschke H, Aro H, Vuorio E. Cathepsin expression during skeletal development. Biochim Biophys Acta 1999;1446:35-46.
23. Graves DT, Jiang Y, Valente AJ. The expression of monocyte chemoattractant protein-1 and other chemokines by osteoblasts. Front Biosci 1999;4:D571-80.
24. Taichman RS, Reilly MJ, Matthews LS. Human osteoblast-like cells and osteosarcoma cell lines synthesize macrophage inhibitory protein 1 alpha in response to interleukin 1 beta and tumour necrosis factor alpha stimulation in vitro. Br J Haematol 2000;108:275-83.
25. Rosen H, Krichevsky A, Polakiewicz RD, Benzakine S, Bar-Shavit Z. Developmental regulation of proenkephalin gene expression in osteoblasts. Mol Endocrinol 1995;9:1621-31.
26. Bjurholm A. Neuroendocrine peptides in bone. Int Orthop 1991;15: 325-9.
27. Svensson J, Lall S, Dickson SL, Bengtsson BA, Romer J, Ahnfelt-Ronne I, Ohlsson C, Jansson JO. Effects of growth hormone and its secretagogues on bone. Endocrine 2001;14:63-6.
28. Fainsod A, Deissler K, Yelin R, Marom K, Epstein M, Pillemer G, Steinbeisser H, Blum M. The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4. Mech Dev 1997;63:39-50.
29. Michel U, Farnworth P, Findlay JK. Follistatins: more than follicle-stimulating hormone suppressing proteins. Mol Cell Endocrinol 1993;91:1-11.
30. McCarthy TL, Ji C, Centrella M. Links among growth factors, hormones, and nuclear factors with essential roles in bone formation. Crit Rev Oral Biol Med 2000;11:409-22.
31. Conover CA. In vitro studies of insulin-like growth factor I and bone. Growth Horm IGF Res 2000;10:5107-10.
32. Mackie EJ, Ramsey S. Modulation of osteoblast behaviour by tenascin. J Cell Sci 1996;109:1597-604.
33. Heinemann DE, Lohmann C, Siggelkow H, Alves F, Engel I, Koster G. Human osteoblast-like cells phagocytose metal particles and express the macrophage marker CD68 in vitro. J Bone Joint Surg Br 2000;82:283-9.
34. Reyes-Botella C, Montes MJ, Vallecillo-Capilla MF, Olivares EG, Ruiz C. Expression of molecules involved in antigen presentation and T cell activation (HLA-DR, CD80, CD86, CD44 and CD54) by cultured human osteoblasts. J Periodontol 2000;71:614-7.
35. Cheng SL, Lecanda F, Davidson MK, Warlow PM, Zhang SF, Zhang L, Suzuki S, St John T, Civitelli R. Human osteoblasts express a repertoire of cadherins, which are critical for BMP-2-induced osteogenic differentiation. J Bone Miner Res 1998;13:633-44.
36. Grzesik WJ, Robey PG. Bone matrix RGD glycoproteins: immunolocalization and interaction with human primary osteoblastic bone cells in vitro. J Bone Miner Res 1994;9:487-96.
37. Kawaguchi J, Ku I, Sugiyama Y, Takeshita S, Kudo A. The transition of cadherin expression in osteoblast differentiation from mesenchymal cells: consistent expression of cadherin-11 in osteoblast lineage. J Bone Miner Res 2001;16:260-9.
38. Boersma CJ, Bloemen M, Hendriks JM, van Berkel EA, Olijve W, van Zoelen EJ. Homeobox proteins as signal transduction intermediates in regulation of NCAM expression by recombinant human bone morphogenetic protein-2 in osteoblast-like cells. Mol Cell Biol Res Commun 1999;1:117-24.
39. Suter DM, Pollerberg GE, Buchstaller A, Giger RJ, Dreyer WJ, Sonderegger P. Binding between the neural cell adhesion molecules axonin-1 and Nr-CAM/Bravo is involved in neuron-glia interaction. J Cell Biol 1995;131:1067-81.
40. Horiuchi K, Amizuka N, Takeshita S, Takamatsu H, Katsuura M, Ozawa H, Toyama Y, Bonewald LF, Kudo A. Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta. J Bone Miner Res 1999;14: 1239-49.
41. Meazzini MC, Toma CD, Schaffer JL, Gray ML, Gerstenfeld LC. Osteoblast cytoskeletal modulation in response to mechanical strain in vitro. J Orthop Res 1998;16:170-80.
42. Lomri A, Marie PJ. Changes in cytoskeletal proteins in response to parathyroid hormone and 1,25-dihydroxyvitamin D in human osteoblastic cells. Bone Miner 1990;10:1-12.
43. Bachner D, Schroder D, Betat N, Ahrens M, Gross G. Apolipoprotein E (ApoE), a Bmp-2 (bone morphogenetic protein) upregulated gene in mesenchymal progenitors (C3H10T1/2), is highly expressed in murine embryonic development. Biofactors 1999;9:11-7.
44. Andrades JA, Nimni ME, Becerra J, Eisenstein R, Davis M, Sorgente N. Complement proteins are present in developing endochondral bone and may mediate cartilage cell death and vascularization. Exp Cell Res 1996;227:208-13.
45. Bradley K, North J, Saunders D, Schwaeble W, Jeziorska M, Woolley DE, Whaley K. Synthesis of classical pathway complement components by chondrocytes. Immunology 1996;88:648-56.
46. Sato T, Hong MH, Jin CH, Ishimi Y, Udagawa N, Shinki T, Abe E, Suda T. The specific production of the third component of complement by osteoblastic cells treated with 1 alpha,25-dihydroxyvitamin D3. FEBS Lett 1991;285:21-4.
47. Pobanz JM, Reinhardt RA, Koka S, Sanderson SD. C5a modulation of interleukin-1 beta-induced interleukin-6 production by human osteoblast-like cells. J Periodontal Res 2000;35:137-45.
48. Tsurukai T, Takahashi N, Jimi E, Nakamura I, Udagawa N, Nogimori K, Tamura M, Suda T. Isolation and characterization of osteoclast precursors that differentiate into osteoclasts on calvarial cells within a short period of time. J Cell Physiol 1998;177:26-35.