UV-Induced Signaling Pathways Associated with Corneal Epithelial Cell Apoptosis

Investigative Ophthalmology and Visual Science

Volumn 44, Issue 12, 2003, Pages 5102-5109

  Lu, Luo ^a   Wang, Ling ^a   Shell, Beth ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CASPASE 3; EGTAZIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; POTASSIUM CHANNEL BLOCKING AGENT; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CORNEA EPITHELIUM; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME PHOSPHORYLATION; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RABBIT; SIGNAL TRANSDUCTION; ULTRAVIOLET C RADIATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CALCIUM; CASPASE 3; CASPASES; EGTAZIC ACID; EPITHELIUM, CORNEAL; HUMANS; IMMUNOBLOTTING; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RABBITS; ULTRAVIOLET RAYS;

EID: 0344420064     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.03-0591     Document Type: Article

References (49)

1. Rosette C, Karin M. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science. 1996;274:1194-1197.
2. Kleiman NJ, Wang RR, Spector A. Ultraviolet light induced DNA damage and repair in bovine lens epithelial cells. Curr Eye Res. 1990;9:1185-1193.
3. Galcheva-Gargova Z, Derijard B, Wu IH, Davis RJ. An osmosensing signal transduction pathway in mammalian cells. Science. 1994;265:806-808.
4. Kallunki T, Su B, Tsigelny I, et al. JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation. Genes Dev. 1994;8:2996-3007.
5. Minden A, Lin A, Claret FX, Abo A, Karin M. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell. 1995;81:1147-1157.
6. Wang L, Xu D, Dai W, Lu L. An ultraviolet-activated K+ channel mediates apoptosis of myeloblastic leukemia cells. J Biol Chem. 1999;274:3678-3685.
7. Kitagawa D, Tanemura S, Ohata S, et al. Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation: its implication in an anti-apoptotic function. J Biol Chem. 2002;277:366-371.
8. Derijard B, Hibi M, Wu IH, et al. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell. 1994;76:1025-1037.
9. Devary Y, Gottlieb RA, Smeal T, Karin M. The mammalian ultraviolet response is triggered by activation of Src tyrosine kinases. Cell. 1992;71:1081-1091.
10. Engelberg D, Klein C, Martinetto H, Struhl K, Karin M. The UV response involving the Ras signaling pathway and AP-I transcription factors is conserved between yeast and mammals. Cell. 1994;77:381-390.
11. Hibi M, Lin A, Smeal T, Minden A, Karin M. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 1993;7:2135-2148.
12. Radler-Pohl A, Sachsenmaier C, Gebel S, et al. UV-induced activation of AP-1 involves obligatory extranuclear steps including Raf-1 kinase. EMBO J. 1993;12:1005-1012.
13. Knebel A, Rahmsdorf HJ, Ullrich A, Herrlich P. Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents. EMBO J. 1996;15:5314-5325.
14. Buscher M, Rahmsdorf HJ, Litfin M, Karin M, Herrlich P. Activation of the c-fos gene by UV and phorbol ester: different signal transduction pathways converge to the same enhancer element. Oncogene. 1988;3:301-311.
15. Devary Y, Gottlieb RA, Lau LF, Karin M. Rapid and preferential activation of the c-jun gene during the mammalian UV response. Mol Cell Biol. 1991;11:2804-2811.
16. Herrlich P, Ponta H, Rahmsdorf HJ. DNA damage-induced gene expression: signal transduction and relation to growth factor signaling (review). Rev Physiol Biochem Pharmacol. 1992;119:187-223.
17. Bortner CD, Hughes FM Jr, Cidlowski JA. A primary role for K+ and Na+ efflux in the activation of apoptosis. J Biol Chem. 1997;272:32436-32442.
18. Duprat F, Guillemare E, Romey G, et al. Susceptibility of cloned K+ channels to reactive oxygen species. Proc Natl Acad Sci USA. 1995;92:11796-11800.
19. Xu B, Wilson BA, Lu L. Induction of human myeloblastic ML-1 cell G1 arrest by suppression of K+ channel activity.. Am J Physiol. 1996;271:C2037-C2042.
20. Yu SP, Yeh CH, Sensi SL, et al. Mediation of neuronal apoptosis by enhancement of outward potassium current. Science. 1997;278:114-117.
21. Frisch SM, Vuori K, Kelaita D, Sicks S. A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA. J Cell Biol. 1996;135:1377-1382.
22. Walev I, Reske K, Palmer M, Valeva A, Bhakdi S. Potassium-inhibited processing of IL-1 beta in human monocytes. EMBO J. 1995;14:1607-1614.
23. Cahill MA, Peter ME, Kischkel FC, et al. CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases. Oncogene. 1996;13:2087-2096.
24. Eldadah BA, Yakovlev AG, Faden AI. The role of CED-3-related cysteine proteases in apoptosis of cerebellar granule cells. J Neurosci. 1997;17:6105-6113.
25. Schulz JB, Weller M, Klockgether T. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J Neurosci. 1996;16:4696-4706.
26. Kang SS, Wang L, Kao WW, Reinach PS, Lu L. Control of SV-40 transformed RCE cell proliferation by growth-factor-induced cell cycle progression. Curr Eye Res. 2001;23:397-405.
27. Xu D, Wang L, Dai W, Lu L. A requirement for K+-channel activity in growth factor-mediated extracellular signal-regulated kinase activation in human myeloblastic leukemia ML-1 cells. Blood. 1999;94:139-145.
28. Lu L, Yang T, Markakis D, Guggino WB, Craig RW. Alterations in a voltage-gated K+ current during the differentiation of ML-1 human myeloblastic leukemia cells. J Membr Biol. 1993;132:267-274.
29. Sanchez I, Hughes RT, Mayer BJ, et al. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature. 1994;372:794-798.
30. Pizarro RA, Orce LV. Membrane damage and recovery associated with growth delay induced by near-UV radiation in Escherichia coli K-12. Photochem Photobiol. 1988;47:391-397.
31. Petit F, Divoux D, Chancerelle Y, Kergonou JF, Nouvelot A. Immunological approach to investigating membrane cell damages induced by lipoperoxidative stress: application to far UV-irradiated erythrocytes. Biol Trace Elem Res. 1995;47:17-27.
32. Schwarz T. UV light affects cell membrane and cytoplasmic targets. J Photochem Photobiol B. 1998;44:91-96.
33. Gentz R, Rauscher FJ III, Abate C, Curran T. Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains. Science. 1989;243:1695-1699.
34. Hirai SI, Ryseck RP, Mechta F, Bravo R, Yaniv M. Characterization of junD: a new member of the jun proto-oncogene family. EMBO J. 1989;8:1433-1439.
35. Li T, Dai W, Lu L. Ultraviolet-induced junD activation and apoptosis in myeloblastic leukemia ML-1 cells. J Biol Chem. 2002;277:32668-32676.
36. Ryder K, Nathans D. Induction of protooncogene c-jun by serum growth factors. Proc Natl Acad Sci USA. 1988;85:8464-8467.
37. Ryder K, Lanahan A, Perez-Albuerne F, Nathans D. jun-D: a third member of the jun gene family. Proc Natl Acad Sci USA. 1989;86:1500-1503.
38. Ryseck RP, Bravo R. c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins. Oncogene. 1991;6:533-542.
39. Smeal T, Angel P, Meek J, Karin M. Different requirements for formation of Jun:Jun and Jun:Fos complexes. Genes Dev. 1989;3:2091-2100.
40. Karin M, Liu Z, Zandi E. AP-1 function and regulation (review). Curr Opin Cell Biol. 1997;9:240-246.
41. Lu ML, Sato M, Cao B, Richie JP. UV irradiation-induced apoptosis leads to activation of a 36-kDa myelin basic protein kinase in HL-60 cells. Proc Natl Acad Sci USA. 1996;93:8977-8982.
42. Kitagawa D, Tanemura S, Ohata S, et al. Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation: its implication in an anti-apoptotic function. J Biol Chem. 2002;277:366-371.
43. Klein JD, Lamitina ST, O'Neill WC. JNK is a volume-sensitive kinase that phosphorylates the Na-K-2Cl cotransporter in vitro. Am J Physiol. 1999;277:C425-C431.
44. Koh YH, Che W, Higashiyama S, et al. Osmotic stress induces HB-EGF gene expression via Ca(2+)/Pyk2/JNK signal cascades in rat aortic smooth muscle cells. J Biochem (Tokyo). 2001;130:351-358.
45. Bildin VN, Yang H, Crook RB, Fischbarg J, Reinach PS. Adaptation by corneal epithelial cells to chronic hypertonic stress depends on upregulation of Na:K:2Cl cotransporter gene and protein expression and ion transport activity. J Membr Biol. 2000;177:41-50.
46. Lewis RS, Cahalan MD. Potassium and calcium channels in lymphocytes (review). Ann Rev Immunol. 1995;13:623-653.
47. Koh JY, Wie MB, Gwag BJ, et al. Staurosporine-induced neuronal apoptosis. Exp Neurol. 1995;135:153-159.
48. Rich A, Rae JL. Calcium entry in rabbit corneal epithelial cells: evidence for a nonvoltage dependent pathway. J Membr Biol. 1995 Mar;144:177-184.
49. Yan M, Dai T, Deak JC, et al. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature. 1994;372:798-800.