Antisense in vivo knockdown of synaptotagmin I and synapsin I by HVJ-liposome mediated gene transfer modulates ischemic injury of hippocampus in opposing ways

Neuroscience Research

Volumn 45, Issue 3, 2003, Pages 285-296

  Iwakuma, Miwa ^a,b   Anzai, Takeshi ^a,c   Kobayashi, Shizuka ^a,b   Ogata, Masanori ^a   Kaneda, Yasufumi ^d   Ohno, Kousaku ^b   Saji, Makoto ^a  

^a KITASATO UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Antisense oligodeoxynucleotides; Hippocampus; HVJ liposome mediated gene transfer method; Ischemic neurodegeneration; Synapsin I; Synaptotagmin I

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; LIPOSOME; PROTEIN SUBUNIT; SYNAPSIN I; SYNAPTOTAGMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN REGION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; FOREBRAIN; HIPPOCAMPUS; INJECTION; LATERAL BRAIN VENTRICLE; MALE; NEUROPROTECTION; NEUROTRANSMITTER RELEASE; NONHUMAN; PARAINFLUENZA VIRUS 1; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SYNAPSE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BRAIN ISCHEMIA; CALCIUM-BINDING PROTEINS; DOWN-REGULATION; GENE TRANSFER TECHNIQUES; HIPPOCAMPUS; LIPOSOMES; MEMBRANE GLYCOPROTEINS; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; PYRAMIDAL CELLS; RATS; SYNAPSINS; SYNAPTOTAGMIN I; SYNAPTOTAGMINS;

EID: 0344406724     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(02)00233-X     Document Type: Article

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