Protective effect of a low dose of colchicine on the delayed cell death of hippocampal CA1 neurons following transient forebrain ischemia

Brain Research

Volumn 774, Issue 1-2, 1997, Pages 229-233

  Kimura, Mitsuhiro ^a   Saji, Makoto ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

CA1 neuron; Colchicine; Delayed neuronal death; Forebrain ischemia; Hippocampus; Rat

Indexed keywords

COLCHICINE; GLIAL FIBRILLARY ACIDIC PROTEIN; HORSERADISH PEROXIDASE; SODIUM CHLORIDE; THIONINE; WHEAT GERM AGGLUTININ;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; FOREBRAIN; HIPPOCAMPUS; INTRACEREBRAL DRUG ADMINISTRATION; MALE; NERVE CELL NECROSIS; NERVE FIBER TRANSPORT; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031558633     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(97)81710-6     Document Type: Article

References (20)

1. Amaral D.G., Kurz J. An analysis of the origins of the cholinergic and noncholinergic septal projections to the hippocampal formation of the rat. J. Comp. Neurol. 240:1985;37-59.
2. Buchan A.M., Pulsinelli W.A. Septo-hippocampal deafferentation protects CA1 neurons against ischemic injury. Brain Res. 512:1990;7-14.
3. Garland D., Teller D.C. A reexamination of the reaction between colchicine and tubulin. Ann. NY Acad. Sci. 253:1975;232-238.
4. Gill R., Nordholm L., Lodge D. The protective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischemia model. Brain Res. 580:1992;35-43.
5. Green E.J., Dietrich W.D., van Dijk F., Busto R., Markgraf C.G., McCabe P.M., Ginsberg M.D., Schneiderman N. Protective effects of brain hypothermia on behavior and histopathology following global cerebral ischemia in rats. Brain Res. 580:1992;197-204.
6. Johansen F.F., Jørgensen M.B., Diemer N.H. Ischemic CA-1 pyramidal cell loss is prevented by preischemic colchicine destruction of dentate gyrus granule cells. Brain Res. 377:1986;344-347.
7. Jørgensen M.B., Johansen F.F., Diemer N.H. Removal of the entorhinal cortex protects hippocampal CA-1 neurons from ischemic damage. Acta Neuropathol. (Berl.). 73:1987;189-194.
8. Kirino T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 239:1982;57-69.
9. Maglóczky Z., Acsády L., Freund T.F. Principal cells are the postsynaptic targets of supramammillary afferents in the hippocampus of the rat. Hippocampus. 4:1994;322-334.
10. Onodera H., Sato G., Kogure K. Lesions to Schaffer collaterals prevent ischemic death of CA1 pyramidal cells. Neurosci. Lett. 68:1986;169-174.
11. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, Academic Press, San Diego, CA, 1986.
12. Perisic M., Cuenod M. Synaptic transmission depressed by colchicine blockade of axoplasmic flow. Science. 175:1972;1140-1142.
13. Pilar G., Landmesser L. Axotomy mimicked by localized colchicine application. Science. 177:1972;1116-1118.
14. Pollard H., Héron A., Moreau J., Ben-Ari Y., Khrestchatisky M. Alteration of the GluR-B AMPA receptor subunit Flip/Flop expression in kainate-induced epilepsy and ischemia. Neuroscience. 57(3):1993;545-554.
15. Pulsinelli W.A., Brierley J.B. A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke. 10:1979;267-272.
16. Saji M., Cohen M., Blau A.D., Wessel T.C., Volpe B.T. Transient forebrain ischemia induces delayed injury in the substantia nigra reticulata: degeneration of GABA neurons, compensatory expression of GAD mRNA. Brain Res. 643:1994;234-244.
17. Sheardown M.J., Nielsen E.O., Hansen A.J., Jacobsen P., Honoré T. 2,3-Dihydroxy-6-nitro-7-sulfamonyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia. Science. 247:1990;571-574.
18. Simon R.P., Swan J.H., Griffiths T., Meldrum B.S. Blockade of N-methyl-D-asparte receptors may protect against ischemic damage in the brain. Science. 226:1984;850-852.
19. Tandon P., Harry G.J., Tilson H.A. Colchicine-induced alteration in receptor-stimulated phosphoinositide hydrolysis in the rat hippocampus. Brain Res. 477:1989;308-318.
20. Tilson H.A., Rogers B.C., Grimers L., Harry G.J., Peterson N.J., Hong J.S., Dyer R.S. Time-dependent neurobiological effects of colchicine administered directly into the hippocampus of rats. Brain Res. 408:1987;163-172.