Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68

Molecular Cancer Research

Volumn 1, Issue 1, 2002, Pages 48-55

  Hong, Wei ^a   Resnick, Ross J ^c   Rakowski, Carrie ^a   Shalloway, David ^c   Taylor, Steven J ^d   Blobel, Gerd A ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Department of Obstetrics Gynecology   (United States)

^d University of California Berkeley   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; MESSENGER RNA; ONCOPROTEIN; ONCOPROTEIN E1A; PROTEIN P53; PROTEIN SAM68; PROTEIN TYROSINE KINASE; REV PROTEIN; RNA BINDING PROTEIN; TRANSCRIPTION COFACTOR CBP; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL STRAIN 3T3; CELL STRAIN COS1; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA PROCESSING; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

3T3 CELLS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BINDING SITES; CARRIER PROTEINS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; DNA-BINDING PROTEINS; GENES, REPORTER; GENETIC VECTORS; HUMANS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MICE; RECOMBINANT FUSION PROTEINS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; RNA-BINDING PROTEINS; SRC-FAMILY KINASES; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0344321888     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Goodman, R. H. and Smolik, S. CBP/p300 in cell growth, transformation, and development. Genes Dev., 14: 1553-1577, 2000.
2. Blobel, G. A. CBP/p300: molecular integrators of hematopoietic transcription. Blood, 95: 745-755, 2000.
3. Chan, H. M. and La Thangue, N. B. p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J. Cell Sci., 114: 2363-2373, 2001.
4. Bannister, A. J. and Kouzarides, T. The CBP co-activator is a histone acetyltransferase. Nature (Lond.), 384: 641-643, 1996.
5. Ogryzko, V. V., Schlitz, L. R., Russanova, V., Howard, B. H., and Nakatani, Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell, 87: 953-959, 1996.
6. Gu, W. and Roeder, R. G. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell, 90: 595-606, 1997.
7. Eckner, R., Ewen, M. E., Newsome, D., Gerdes, M., DeCaprio, J. A., Lawrence, J. B., and Livingston, D. M. Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kd protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev., 8: 869-884, 1994.
8. Arany, Z., Newsome, D., Oldread, E., Livingston, D. M., and Eckner, R. A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Nature, 374: 81-84, 1995.
9. Lundblad, J. R., Kwok, R. P., Laurance, M. E., Harter, M. L., and Goodman, R. H. Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP. Nature, 374: 85-88, 1995.
10. Yang, X-J., Ogryzko, V. V., Nishikawa, J., Howard, B. H., and Nakatani, Y. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature (Lond.), 382: 319-324, 1996.
11. O'Connor, M. J., Zimmermann, H., Nielsen, S., Bernard, H. U., and Kouzarides, T. Characterization of an E1A-CBP interaction defines a novel transcriptional adapter motif (TRAM) in CBP/p300. J. Virol., 73: 3574-3581, 1999.
12. Hamamori, Y., Sartorelli, V., Ogryzko, V., Puri, P. L., Wu, H. Y., Wang, J. Y., Nakatani, Y., and Kedes, L. Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A. Cell, 96: 405-413, 1999.
13. Chakravarti, D., Ogryzko, V., Kao, H. Y., Nash, A., Chen, H., Nakatani, Y., and Evans, R. M. A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity. Cell, 96: 393-403, 1999.
14. Perissi, V., Dasen, J. S., Kurokawa, R., Wang, Z., Korzus, E., Rose, D. W., Glass, C. K., and Rosenfeld, M. G. Factor-specific modulation of CREB-binding protein acetyltransferase activity. Proc. Natl. Acad. Sci. USA, 96: 3652-3657, 1999.
15. Ait-Si-Ali, S., Ramirez, S., Barre, F. X., Dkhissi, F., Magnaghi-Jaulin, L., Girault, J. A., Robin, P., Knibiehler, M., Pritchard, L. L., Ducommun, B., Trouche, D., and Harel-Bellan, A. Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A. Nature (Lond.), 396: 184-186, 1998.
16. Taylor, S. J. and Shalloway, D. An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis. Nature, 368: 867-871, 1994.
17. Fumagalli, Si., Totty, N. F., Hsuan, J. J., and Courtneidge, S. A. A target for Src in mitosis. Nature, 368: 871-874, 1994.
18. Richard, S. Association of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C γ-1. Mol. Cell. Biol., 15: 186-197, 1995.
19. Taylor, S. J., Anafi, M., Pawson, T., and Shalloway, D. Functional interaction between c-Sr-and its mitotic target, Sam68. J. Biol. Chem., 270: 10120-10124, 1995.
20. Derry, J. J., Richard, S., Valderrama Carvajal, H., Ye, X., Vasioukhin, V., Cochrane, A. W., Chen, T., and Tyner, A. L. Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability. Mol. Cell. Biol., 20: 6114-6126, 2000.
21. Wong, G., Muller, O., Clark, R., Conroy, L., Moran, M. F., Polakis, P., and McCormick, F. Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62. Cell, 69: 551-558, 1992.
22. Lin, Q., Taylor, S. J., and Shalloway, D. Specificity and determinants of Sam68 RNA binding. Implications for the biological function of K homology domains. J. Biol. Chem., 272: 27274-27280, 1997.
23. Vernet, C. and Artzt, K. STAR, a gene family involved in signal transduction and activation of RNA. Trends Genet., 13: 479-484, 1997.
24. Jones, A. R. and Schedl, T. Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68. Genes Dev., 9: 1491-1504, 1995.
25. Chen, T., Boisvert, F. M., Bazett-Jones, D. P., and Richard, S. A role for the GSG domain in localizing Sam68 to novel nuclear structures in cancer cell lines. Mol. Biol. Cell, 10: 3015-3033, 1999.
26. Chen, T., Damaj, B. B., Herrera, C., Lasko, P., and Richard, S. Self-association of the single-KH-domain family members Sam68, GRP33, GLD-1 and Qk1: role of the KH domain. Mol. Cell. Biol., 17: 5707-5718, 1997.
27. Reddy, T. R., Xu, W., Mau, J. K., Goodwin, C. D., Suhasini, M., Tang, H., Frimpong, K., Rose, D. W., and Wong-Staal, F. Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev. Nat. Med., 5: 635-642, 1999.
28. Tsang, A. P., Visvader, J. E., Turner, C. A., Fujiwara, Y., Yu, C., Weiss, M. J., Crossley, M., and Orkin, S. H. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell, 90: 109-119, 1997.
29. LaMorte, V. J. Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body. Proc. Natl. Acad. Sci. USA, 95: 4991-4996, 1998.
30. Hope, T. J., Huang, X. J., McDonald, D., and Parslow, T. G. Steroid-receptor fusion of the human immunodeficiency virus type 1 Rev transactivator: mapping cryptic functions of the arginine-rich motif. Proc. Natl. Acad. Sci. USA, 87: 7787-7791, 1990.
31. Martinez-Balbas, M., Bannister, A., Martin, K., Haus-Seuffert, P., Meisternst, M., and Kouzarides, T. The acetyltransferase activity of CBP stimulates transcription. EMBO J., 17: 2886-2893, 1998.
32. Blobel, G. A., Nakajima, T., Eckner, R., Montminy, M., and Orkin, S. H. CREB-binding protein (CBP) cooperates with transcription factor GATA-1 and is required for erythroid differentiation. Proc. Natl. Acad. Sci. USA, 95: 2061-2066, 1998.
33. Liu, K., Li, L., Nisson, P. E., Gruber, C., Jessee, J., and Cohen, S. N. Neoplastic transformation and tumorigenesis associated with sam68 protein deficiency in cultured murine fibroblasts. J. Biol. Chem., 275: 40195-40201, 2000.
34. Hirose, Y. and Manley, J. L. RNA polymerase II and the integration of nuclear events. Genes Dev., 14: 1415-1429, 2000.
35. James, P., Halladay, J., and Craig, E. A. Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics, 144: 1425-1436, 1996.
36. RSK. Cell, 86: 465-474, 1996.
37. Merika, M. and Orkin, S. H. Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with Krüppel family proteins Sp1 and EKLF. Mol. Cell. Biol., 15: 2437-2447, 1995.
38. Andrews, N. and Faller, D. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res., 87: 2499, 1991.
39. Smith, D. B. and Johnson, K. S. Single step purification of polypeptides expressed in E. coli as fusions with GST. Gene, 67: 31-40, 1988.