메뉴 건너뛰기




Volumn 43, Issue 3, 1997, Pages 158-167

Overactivity of tumor necrosis factor-alpha but not interleukin 6 is associated with low natural killer cytotoxic activity in the elderly

Author keywords

Ageing; Interleukin 6; Natural killer cytotoxic activity; Tumor necrosis factor alpha

Indexed keywords

INTERLEUKIN 6; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

EID: 0345130874     PISSN: 0304324X     EISSN: 14230003     Source Type: Journal    
DOI: 10.1159/000213845     Document Type: Article
Times cited : (19)

References (30)
  • 1
    • 0027161033 scopus 로고
    • Weindruch R: Lnterleukin-6 and aging: Blood levels and mononuclear cell production increase with advancing age and in vitro production is modifiable by dietary restriction
    • Ershler WB, Sun WH, Binkley N, Gravcnstein S, Volk MJ, Kamoske G, Klopp RG, Roecker EB, Daynes RA, Weindruch R: lnterleukin-6 and aging: Blood levels and mononuclear cell production increase with advancing age and in vitro production is modifiable by dietary restriction. Lymphokinc Cytokine Res 1993;12:225-230.
    • (1993) Lymphokinc Cytokine Res , vol.12 , pp. 225-230
    • Ershler, W.B.1    Sun, W.H.2    Binkley, N.3    Gravcnstein, S.4    Volk, M.J.5    Kamoske, G.6    Klopp, R.G.7    Roecker, E.B.8    Daynes, R.A.9
  • 3
    • 0025261004 scopus 로고
    • Lack of an association between the presence of tumor necrosis factor or interleukin-1-alpha in the blood and weight loss among elderly patients
    • Mooradian AD, Reed RL, Osterwcil D, Clements N, Scuderi P: Lack of an association between the presence of tumor necrosis factor or interleukin-1-alpha in the blood and weight loss among elderly patients. JAGS 1990;38:397-410.
    • (1990) JAGS , vol.38 , pp. 397-410
    • Mooradian, A.D.1    Reed, R.L.2    Osterwcil, D.3    Clements, N.4    Scuderi, P.5
  • 4
    • 0026497223 scopus 로고
    • Increase of plasma IL-6 concentration with age in healthy subjects
    • Wei J, Xu H, Davies JL, Hcmmings GP: Increase of plasma IL-6 concentration with age in healthy subjects. LifcSci 1993:51:1953.
    • (1993) Lifcsci , vol.51 , pp. 1953
    • Wei, J.1    Xu, H.2    Davies, J.L.3    Hcmmings, G.P.4
  • 5
    • 0027973612 scopus 로고
    • Establishment of the role of 1L6 and TNF receptor 1 using gene knockout mice
    • Bluethmann H, Rothe J, Schultze N, Tkachuk M, Kocbcl P: Establishment of the role of 1L6 and TNF receptor 1 using gene knockout mice. J Leukoc Biol 1994:56:565-570.
    • (1994) J Leukoc Biol , vol.56 , pp. 565-570
    • Bluethmann, H.1    Rothe, J.2    Schultze, N.3    Tkachuk, M.4    Kocbcl, P.5
  • 6
    • 0028244816 scopus 로고
    • Tumor necrosis factor: A pleiotropic cytokine and therapeutic target
    • Tracey KJ, Cerami A: Tumor necrosis factor: A pleiotropic cytokine and therapeutic target. Annu Rev Med 1994;45:491-503.
    • (1994) Annu Rev Med , vol.45 , pp. 491-503
    • Tracey, K.J.1    Cerami, A.2
  • 7
    • 0025260903 scopus 로고
    • Interlcukin-6: An overview
    • Van Snick J: Interlcukin-6: An overview. Ann Rev Immunol 1990:8: 253-278.
    • (1990) Ann Rev Immunol , vol.8 , pp. 253-278
    • Van Snick, J.1
  • 9
    • 0025763192 scopus 로고
    • Involvement of the 55 and 75-kDa tumor necrosis factor receptors in the generation of lym-phokine-activatcd killer cell activity and proliferation of natural killer cells
    • Naume B, Shalaby R, Lesslauer W, Espevik T: Involvement of the 55 and 75-kDa tumor necrosis factor receptors in the generation of lym-phokine-activatcd killer cell activity and proliferation of natural killer cells. J Immunol 1991; 146:3045- 3048.
    • (1991) J Immunol , vol.146
    • Naume, B.1    Shalaby, R.2    Lesslauer, W.3    Espevik, T.4
  • 10
    • 0023276841 scopus 로고
    • Tumor necrosis factor-a enhances cytolytic activity of human natural killer cells
    • Ostcnsc M, Thiele DL, Lipsky PE: Tumor necrosis factor-a enhances cytolytic activity of human natural killer cells. J Immunol 1987; 138: 4185-4191.
    • (1987) J Immunol , vol.138 , pp. 4185-4191
    • Ostcnsc, M.1    Thiele, D.L.2    Lipsky, P.E.3
  • 11
    • 0026085022 scopus 로고
    • Comparison of the effect of IL2 and IL6 on the lytic activity of purified human peripheral blood large lymphocytes
    • Smyth MJ, Ortaldo JR: Comparison of the effect of IL2 and IL6 on the lytic activity of purified human peripheral blood large lymphocytes. J Immunol 1991;146:1380-1384.
    • (1991) J Immunol , vol.146 , pp. 1380-1384
    • Smyth, M.J.1    Ortaldo, J.R.2
  • 12
    • 0022387291 scopus 로고
    • Interleukin-2 production and activity in aged humans
    • Rabinowich H, Goses Y, Reshcf T, Klajman A: Interleukin-2 production and activity in aged humans. MechAgeDev 1985:32:213-226.
    • (1985) Mechagedev , vol.32 , pp. 213-226
    • Rabinowich, H.1    Goses, Y.2    Reshcf, T.3    Klajman, A.4
  • 14
    • 0026573770 scopus 로고
    • Monocytes are responsible for depressed natural killer (NK) activity in both young and elderly low NK responders
    • Mysliwska J, Mysliwski A, Roma-nowski P, Bigda J, Sosnowska D, Foerstcr J: Monocytes are responsible for depressed natural killer (NK) activity in both young and elderly low NK responders. Gerontology 1992;38:41-49.
    • (1992) Gerontology , vol.38 , pp. 41-49
    • Mysliwska, J.1    Mysliwski, A.2    Roma-Nowski, P.3    Bigda, J.4    Sosnowska, D.5    Foerstcr, J.6
  • 16
    • 0022972268 scopus 로고
    • Phenotypic expression of natural killer cell associated membrane antigens and cytolytic function of peripheral blood cells from different aged humans
    • Bender BS, Chrest FJ, Adler WA: Phenotypic expression of natural killer cell associated membrane antigens and cytolytic function of peripheral blood cells from different aged humans. J Clin Lab Immunol 1986:21:31-36.
    • (1986) J Clin Lab Immunol , vol.21 , pp. 31-36
    • Bender, B.S.1    Chrest, F.J.2    Adler, W.A.3
  • 17
    • 0026802522 scopus 로고
    • Immunoscnesccncc of human NK cells: Effects on tumor target recognition, lethal hit and interferon sensitivity
    • Krishnaraj R: Immunoscnesccncc of human NK cells: Effects on tumor target recognition, lethal hit and interferon sensitivity. Immunol Lett 1992;43:89-84.
    • (1992) Immunol Lett , vol.43 , pp. 84-89
    • Krishnaraj, R.1
  • 18
    • 0023225697 scopus 로고
    • Increased number of circulating Leu 11 + (CD 16) large granular lymphocytes and decreased NK activity during human ageing
    • Facchini A, Mariani E, Mariani AR, Papa S, Vitale M, Manzoli FA: Increased number of circulating Leu 11 + (CD 16) large granular lymphocytes and decreased NK activity during human ageing. Clin Exp Immunol 1987;68:340-347.
    • (1987) Clin Exp Immunol , vol.68 , pp. 340-347
    • Facchini, A.1    Mariani, E.2    Mariani, A.R.3    Papa, S.4    Vitale, M.5    Manzoli, F.A.6
  • 19
    • 0024367301 scopus 로고
    • Pathophysiology of the immune system in the elderly subjects with or without diabetes and variations after recombinant interleukin-2
    • Camazzo G, Morine G, Turturici A, Favetty A, Campo ME, Consenza C, Stivala F: Pathophysiology of the immune system in the elderly subjects with or without diabetes and variations after recombinant interleukin-2. Arch Geront Geriatr 1989: 9:163-180.
    • (1989) Arch Geront Geriatr , vol.9 , pp. 163-180
    • Camazzo, G.1    Morine, G.2    Turturici, A.3    Favetty, A.4    Campo, M.E.5    Consenza, C.6    Stivala, F.7
  • 24
    • 0028922552 scopus 로고
    • Influence of age on human marrow
    • Glowacki J: Influence of age on human marrow. Calcif Tissue Int 1995;56(suppl 1):SS0-S51.
    • (1995) Calcif Tissue Int , vol.56 , pp. SS0-S51
    • Glowacki, J.1
  • 25
    • 0027304433 scopus 로고
    • Lnlerlcukin-6 in autoimmune diseases: Role of 1L-6 in physiology and pathology of the immune defense
    • Graeve L, Baumann M, Heinrich PC: lnlerlcukin-6 in autoimmune diseases: Role of 1L-6 in physiology and pathology of the immune defense. Clin Invest 1993;71:664-671.
    • (1993) Clin Invest , vol.71 , pp. 664-671
    • Graeve, L.1    Baumann, M.2    Heinrich, P.C.3
  • 26
    • 0027370354 scopus 로고
    • In vitro production of cytokines by bone surface-derived osteoblastic cells in normal and osteoporotic postmenopausal women: Relationship with cell proliferation
    • Marie PJ, Hott M, Launay JM, Graulet AM, Gueris J: In vitro production of cytokines by bone surface-derived osteoblastic cells in normal and osteoporotic postmenopausal women: Relationship with cell proliferation. J Clin Endocrinol Metab 1991;77:824-830.
    • (1991) J Clin Endocrinol Metab , vol.77 , pp. 824-830
    • Marie, P.J.1    Hott, M.2    Launay, J.M.3    Graulet, A.M.4    Gueris, J.5
  • 28
    • 0026587492 scopus 로고
    • Regulation of lymphokine-activated killer cell induction by human recombinant IL-1 receptor antagonist: Obligate paracrine pathway of IL-1 during lymphokine-activated killer cell induction
    • Fujiwara T, Grimm AE: Regulation of lymphokine-activated killer cell induction by human recombinant IL-1 receptor antagonist: Obligate paracrine pathway of IL-1 during lymphokine-activated killer cell induction. J Immunol 1992;148: 2941-2946.
    • (1992) J Immunol , vol.148 , pp. 2941-2946
    • Fujiwara, T.1    Grimm, A.E.2
  • 30
    • 0023205403 scopus 로고
    • Age-associated alterations in human natural killer cells. I. Increased activity as per conventional and kinetic analysis
    • Krishnaraj R, Blandford G: Age-associated alterations in human natural killer cells. I. Increased activity as per conventional and kinetic analysis. Clin Immunol Immunpa-thof 1987;45:268-285.
    • (1987) Clin Immunol Immunpa-Thof , vol.45 , pp. 268-285
    • Krishnaraj, R.1    Blandford, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.