Pseudohyphal Growth in a Dimorphic Yeast, Candida maltosa, after Disruption of the C-GCN4 Gene, a Homolog of Saccharomyces cerevisia

Bioscience, Biotechnology and Biochemistry

Volumn 66, Issue 9, 2002, Pages 1936-1939

  Takaku, Hiroaki ^a   Horiuchi, Hiroyuki ^a   Takagi, Masamichi ^a   Ohta, Akinori ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Candida maltosa; GCN4; Morphogenesis; Pseudohyphal growth

Indexed keywords

DNA BINDING PROTEIN; FUNGAL RNA; PROTEIN KINASE; SACCHAROMYCES CEREVISIAE PROTEIN;

ARTICLE; CANDIDA; CYTOLOGY; FUNGAL GENE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; TIME;

CANDIDA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; MUTATION; PROTEIN KINASES; RNA, FUNGAL; SACCHAROMYCES CEREVISIAE PROTEINS; TIME FACTORS; TRANSCRIPTION, GENETIC;

CANDIDA; CANDIDA MALTOSA; EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0344257674     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.66.1936     Document Type: Article

References (13)

1. Odds, F. C., Pathogenesis of Candida infections. J. Am. Acad. Dermatol., 31, S2-S5 (1994).
2. Nakazawa, T., Horiuchi, H., Ohta, A., and Takagi, M., Isolation and characterization of EPD1, an essential gene for pseudohyphal growth of a dimorphic yeast, Candida maltosa. J. Bacteriol., 180, 2079-2086 (1998).
3. Nakazawa, T., Takahashi, M., Horiuchi, H., Ohta, A., and Takagi, M., Cloning and characterization of EPD2, a gene required for efficient pseudohyphal formation of a dimorphic yeast, Candida maltosa. Biosci. Biotechnol. Biochem., 64, 369-377 (2000).
4. Nakazawa, T., Motoyama, T., Horiuchi, H., Ohta, A., and Takagi, M., Evidence that part of a centromeric DNA region induces pseudohyphal growth in a dimorphic yeast, Candida maltosa. J. Bacteriol., 179, 5030-5036 (1997).
5. Ohkuma, M., Hwang, C. W., Masuda, Y., Nishida, H., Sugiyama, J., Ohta, A., and Takagi, M., Evolutionary position of n-alkane-assimilating yeast Candida maltosa shown by nucleotide sequence of small-subunit ribosomal RNA gene. Biosci. Biotechnol. Biochem., 57, 1793-1794 (1993).
6. Hinnebusch, A. G., Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae. Microbiol. Rev., 52, 248-273 (1988).
7. Schmitt, M., Brown, T. A., and Trumpower, B. L., A rapid and simple method for preparation of RNA from Saccharomyces cerevisiae. Nucleic Acids Res., 18, 3091 (1990).
8. Mutoh, E., Takaku, H., Ohta, A., and Takagi, M., A gene coding for a ribosomal protein L41 in cyclo-heximide-resistant ribosomes has a promoter which is upregulated under the growth-inhibitory conditions in yeast, Candida maltosa. Biochem. Biophys. Res. Commun., 258, 611-615 (1999).
9. Culter, N. S., Pan, X., Heitman, J., and Cardenas, M. E., The TOR signal transduction cascade controls cellular differentiation in response to nutrients. Mol. Biol. Cell, 12, 4103-4113 (2001).
10. Gimeno, C. J., Ljungdahl, P. O., Styles, C. A., and Fink, G. R., Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: regulation by starvation and RAS. Cell, 68, 1077-1090 (1992).
11. Valenzuela, L., Aranda, C., and Gonzalez, A., TOR modulates GCN4-dependent expression of genes turned on by nitrogen limitation. J. Bacteriol., 183, 2331-2334 (2001).
12. Grundmann, O., Mosch, H.-U., and Braus, G. H., Repression of GCN4 mRNA translation by nitrogen starvation in Saccharomyces cerevisiae. J. Biol. Chem., 276, 25661-25671 (2001).
13. Takaku, H., Mutoh, E., Horiuchi, H., Ohta, A., and Takagi, M., Ray38p, a homolog of a purine motif triple-helical DNA-binding protein, Stmlp, is a ribosome-associated protein and dissociated from ribosomes prior to the induction of cycloheximide resistance in Candida maltosa. Biochem. Biophys. Res. Commun., 284, 194-202 (2001).