Diastereoselective addition of chiral (2-lithiophenyl)acetaldehyde acetals to various imines as key step in the asymmetric synthesis of 1- aryltetrahydroisoquinolines, part 4

European Journal of Organic Chemistry

Volumn , Issue 2, 1999, Pages 503-517

  Wünsch, Bernhard ^a   Nerdinger, Sven ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b CarboGen Laboratories AG   (Switzerland)

Author keywords

Asymmetric synthesis; Diastereoselective addition to imines; Enantiomerically pure (2 bromophenyl)acetaldehyde acetals; Halogen metal exchange; NMDA antagonists; Tetrahydroisoquinolines

Indexed keywords

(2 BROMOPHENYL)ACETALDEHYDE; (2 LITHIOPHENYL)ACETALDEHYDE; 1 PHENYL 1,2,3,4 TETRAHYDROISOQUINOLINE; 1,3 DIOXOLANE DERIVATIVE; ACETAL DERIVATIVE; ACETALDEHYDE; AMINE; AMMONIA; CARBAMIC ACID DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SODIUM; SULFONAMIDE; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CYCLIZATION; DIASTEREOISOMER; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STEREOCHEMISTRY;

EID: 0344246937     PISSN: 1434193X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-0690(199902)1999:2<503::AID-EJOC503>3.0.CO;2-I     Document Type: Article

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