The cardiovascular effects of the administration of L-NAME during the early posthemorrhagic period

General Pharmacology

Volumn 30, Issue 5, 1998, Pages 763-769

  Bagchi, D ^a   Garg, A ^a   Krohn, R L ^a   Bagchi, M ^a   Bagchi, D J ^a   Balmoori, J ^a   Stohs, S J ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF PHARMACY AND HEALTH PROFESSIONS   (United States)

Author keywords

Cardiovascular parameters; Hemorrhagic shock; L NAME

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL BLOOD; ARTICLE; BLEEDING; BOLUS INJECTION; BRADYCARDIA; CARDIOVASCULAR EFFECT; CARDIOVASCULAR PARAMETERS; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; HEART RATE; HEMORRHAGIC SHOCK; HYPERKALEMIA; HYPOVOLEMIA; INTRAVENOUS DRUG ADMINISTRATION; MEAN ARTERIAL PRESSURE; METABOLIC ACIDOSIS; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; BLOOD PRESSURE; BLOOD PROTEINS; ELECTROLYTES; ENZYME INHIBITORS; HEART; HEART RATE; HYDROGEN-ION CONCENTRATION; NG-NITROARGININE METHYL ESTER; RABBITS; SHOCK, HEMORRHAGIC;

EID: 0344110296     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(97)00333-9     Document Type: Article

References (36)

1. Afanas'ev I. B., Dorozhko A. I., Brodskii A. V., Kostyuk V. A., Potapovitch A. I. Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation. Biochem. Pharmac. 38:1989;1763-1769.
2. Ames B. N. Pollution, pesticides and cancer. J. AOAC Int. 75:1992;1-5.
3. Babior B. M., Kipner R. S., Cerutte J. T. The production by leukocytes of superoxide. a potential bactericidal agent J. Clin. Invest. 52:1993;741-744.
4. Bagchi D., Hassoun E. A., Bagchi M., Stohs S. J. Protective effects of antioxidants against endrin-induced hepatic lipid peroxidation, DNA damage, and excretion of urinary lipid metabolites. Free Radical Biol. Med. 15:1993;217-222.
5. Bagchi M., Stohs J. J. In vitro induction of reactive oxygen species by 2,3,7,8-tetrachlorodibenzo-p-dioxin, endrin and lindane in rat peritoneal macrophages and hepatic mitochondria and microsomes. Free Radical Biol. Med. 14:1993;11-18.
6. Bors W., Saran M. Radical scavenging by flavonoid antioxidants. Free Radical Res. Commun. 2:1987;289-294.
7. Brandi M. L. Flavonoids. biochemical effects and therapeutic applications Bone Miner. 19:1992;S3-S14.
8. Buege J. A., Aust D. S. Microsomal lipid peroxidation. Methods Enzymol. 52:1978;302-310.
9. Buening M. K., Chang R. L., Huang M. T., Fortner J. G., Wood A. W., Conney A. H. Activation and inhibition of benzo(a)pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occurring flavonoids. Cancer Res. 41:1981;67-72.
10. Buettner G. R. The pecking order of free radicals and antioxidants. lipid peroxidation, α-tocopherol, and ascorbate Arch. Biochem. Biophys. 300:1993;535-543.
11. Chen Z. Y., Chan P. T. Antioxidant activity of green tea catechins in canola oil. Chem. Phys. Lipids. 82:1996;163-172.
12. Chen Z. Y., Chan P. T., Ho K. Y., Fung K. P., Wang J. Antioxidative activity of natural flavonoids is governed by number and location of their aromatic hydroxyl groups. Chem. Phys. Lipids. 79:1996;157-163.
13. Fisher M. S., Adams M. L. Suppression of tumor promoter- induced chemiluminescence in mouse epidermal cells by several inhibitors of arachidonic acid metabolism. Cancer Res. 45:1985;3130-3136.
14. Frankel E. N., Kanner J., German J. B., Parks E., Kinsells J. E. Inhibition in vitro of oxidation of human low-density lipoproteins by phenolic substance in wine. Lancet. 341:1993;1-4.
15. Gonzalez J. G., delle-Monache G., delle-Monache F., Marini-Bettolo G. B. Chuchuhuasha - a drug used in folk medicine in the Amazonian and Andean areas. a chemical study of Maytenus leavis J. Ethnopharmac. 5:1982;73-77.
16. Halliwell B. Oxidative stress, nutrition and health. experimental strategies for optimization of nutritional antioxidant intake in humans Free Radical Res. 25:1996;57-74.
17. Halliwell B., Cross C. E. Reactive oxygen species, antioxidants and acquired immunodeficiency syndrome. Arch. Int. Med. 157:1991;29-32.
18. Halliwell B., Gutteridge J. M. C., Cross C. E. Free radicals, antioxidants and human disease. where are we now? J. Lab. Clin. Med. 119:1992;598-620.
19. Hanefeld M., Herrmann K. On the occurrence of proanthocyanidins, leucoanthocyanidins and catechins in vegetables. Z. Lebensm.-Unters.-Forsch. 161:1976;243-248.
20. Havsteen B. Flavonoids. a class of natural products of high pharmacological potency Biochem. Pharmac. 32:1983;1141-1148.
21. Hocman G. Prevention of cancer. vegetables and plants Comp. Biochem. Physiol. 93B:1989;201-212.
22. Jovanovic S. V., Steenken S., Tosic M., Marjanovic B., Simic M. G. Flavonoids as antioxidants. J. Am. Chem. Soc. 116:1994;4846-4851.
23. Kehrer J. P. Free radicals as mediators of tissue injury and disease. Crit. Rev. Toxicol. 23:1993;21-48.
24. Kinsella J. E., Frankel E., German B., Kanner J. Possible mechanism for the protective role of antioxidants in wine and plant foods. Food Technol. April:1993;85-89.
25. Kolodziej H., Haberland C., Woerdenbag H. J., Konings A. W. T Moderate cytotoxicity of proanthocyanidins to human tumor cell lines. Phytother. Res. 9:1995;410-415.
26. Masquelier J., Michaud J., Laparra J., Dumon M. C. Flavonoids and pycnogenols. Int. J. Vitam. Nutr. Res. 49:1979;307-311.
27. Pitot H. C., Dragan Y. P. Facts and theories concerning the mechanisms of carcinogenesis. FASEB J. 5:1991;2280-2286.
28. 2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen. FASEB J. 7:1993;453-463.
29. Rice-Evans C. A., Miller N. J., Paganda G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radical Biol. Med. 20:1996;933-956.
30. Ritchey E. E., Wallin J. D., Shah S. V. Chemiluminescence and superoxide anion production by leukocytes from chronic hemodialysis patients. Kidney Int. 19:1981;349-358.
31. Salah N., Miller N. J., Paganga G., Tijburg L., Bolwell G. P., Rice-Evans C. Polyphenolic flavonols as scavengers of aqueous phase radicals and as chain-breaking antioxidants. Arch Biochem. Biophys. 322:1995;339-346.
32. Schwartzman R. A., Cidlowski J. A. Apoptosis. the biochemistry and molecular biology of programmed cell death Endocr. Rev. 14:1993;133-151.
33. Shahidi F., Wanasundara P. K. J. Phenolic antioxidants. Crit. Rev. Food Sci. Nutr. 32:1992;67-103.
34. Stohs S. J., Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Radical Biol. Med. 18:1995;321-336.
35. Suzuki N. Antioxidative activity of some biologically active compounds with active oxygen species. Spectrum. 6:1993;21-27.
36. Witz G., Czerniecki B. J. Tumor promoters differ in their ability to stimulate superoxide anion radical production by murine peritoneal exudate cells following in vivo administration. Carcinogenesis. 10:1989;807-811.