Serum Immunoglobulins (IgG, IgA, IgM) in Chronic Hepatitis C. A Comparison with Non-cirrhotic Alcoholic Liver Disease

Hepato-Gastroenterology

Volumn 50, Issue 54, 2003, Pages 2121-2126

  Gonzalez Quintela A ^a,b   Alende, M R ^a   Gamallo, R ^a   Gonzalez Gil P ^a   Lopez Ben S ^a   Tome S ^a   Otero, E ^a   Torre, J A ^a  

^a HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^b Instituto de Salud Carlos III   (Spain)

Author keywords

Alcohol; Hepatitis c virus; IgA; IgG; IgM

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M;

ADOLESCENT; ADULT; AGED; ALCOHOL LIVER CIRRHOSIS; ARTICLE; CHRONIC HEPATITIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DISEASE SEVERITY; FATTY LIVER; FEMALE; HEALTH STATUS; HEPATITIS C; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NEPHELOMETRY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; FATTY LIVER, ALCOHOLIC; FEMALE; HEPATITIS C, CHRONIC; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LIVER DISEASES, ALCOHOLIC; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; NEPHELOMETRY AND TURBIDIMETRY; REFERENCE VALUES; SPAIN;

EID: 0344099057     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Triger DR, Wright R: Hyperglobulinaemia in liver disease. Lancet 1973; ii:1494-1496.
2. Pomier-Layrargues G, Huet PM, Richer G, Marleau D, Viallet A: Hyperglobulinemia in alcoholic cirrhosis. Relationship with portal hypertension and intrahepatic portal-systemic shunting as assesed by Kupffer cell uptake. Dig Dis Sci 1980; 25:489-493.
3. Sherlock S, Dooley J: Hepatic cirrhosis. In: Sherlock S, Dooley J (Eds.). Diseases of the liver and the biliary system. Oxford: Blackwell Science, 1997; p. 371.
4. Martin DM, Vroon DH, Nasrallah SM: Value of serum immunoglobulins in the diagnosis of liver disease. Liver 1984; 4:214-218.
5. Gluud C, Tage-Jensen U: Autoantibodies and immunoglobulins in alcoholic steatosis and cirrhosis. Acta Med Scand 1983; 214:61-66.
6. Bayley RJ, Krasner N, Eddleston ALWF, Williams R, Tee DEH, Doniach D, Kennedy LA, Batchelor JR: Histocompatibility antigens, autoantibodies, and immunoglobulins in alcoholic liver disease. Br Med J 1976; 2:727-729.
7. Van de Wiel A, Van Hattum J, Schuurman HJ, Kater L: Immunoglobulin A in the diagnosis of alcoholic liver disease. Gastroenterology 1988; 94:457-462.
8. González-Quintela A, Vidal C, Gude F, Tomé S, Lojo S, Lorenzo M, Becerra EP, Martínez-Vázquez JM, Barrio E: Increased serum IgE in alcohol abusers. Clin Exp Allergy 1995; 25:756-764.
9. Vidal C, Gonzalez Quintela A, Millan I, Gude F, Cuervas-Mons V: Serum IgE in liver cirrhosis: contrasting results in alcoholic and non-alcoholic patients. Clin Exp Allergy 1994; 24:540-548.
10. Sancho J, Egido J, Sanchez-Crespo M, Blasco R: Detection of monomeric and polymeric IgA containing immune complexes in serum and kidney from patients with alcoholic liver diseases. Clin Exp Immunol 1982; 47:327-335.
11. Van de Wiel A, Schuurman HJ, van Riessen D, Haaijman JJ, Delacroix DL, van Hattum J, Blok AP, Kater L: Characteristics of IgA deposits in liver and skin of patients with liver disease. Am J Clin Pathol 1986; 86:724-730.
12. Bene Mc, DeKorwin JD, de Ligny BH, Aymard B, Kessler M, Faure GC: IgA nephropathy and alcoholic liver cirrhosis. A prospective necropsy study. Am J Clin Pathol 1988; 89:769-773.
13. Smith SM, Hoy WE: Dermal vascular IgA deposits in IgA nephropathy secondary to alcohol abuse. J Cutan Pathol 1990; 17:193-196.
14. Feriozzi S, Onetti A, Faraggiana T, Amini M, Ancarani E: Henoch-Schonlein disease with IgA nephropathy associated with chronic alcoholic liver disease. Nephrol Dial Transplant 1995; 10:1231-1233.
15. Saklayen MG, Schroeter AL, Nafz MA, Jalil K: IgA deposition in the skin of patients with alcoholic liver disease. J Cutan Pathol 1996; 23:12-18.
16. Van de Wiel A, Schuurman HJ, Kater L: Alcoholic liver disease: an IgA associated disorder. Scand J Gastroenterol 1987; 22:1025-1030.
17. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M: Isolation of a cDNA clone derived from a blood borne non-A, non-B viral hepatitis genome. Science 1989; 244:359-362.
18. Czaja AJ: Chronic active hepatitis: the challenge for a new nomenclature. Ann Intern Med 1993; 119:510-517.
19. EASL Consensus Panel: EASL International Consensus Conference on hepatitis C. Consensus statement: J Hepatol 1999; 30:956-961.
20. Musset L, Lunel F, Cacoub P, Mannant PR, Silvain C, Lacombe C, Opolon P, Preud'homme JL: Increased serum immunoglobulin G1 levels in hepatitis C virus infection. Hepatology 1995; 21:1755-1757.
21. Illan Y, Shouval D, Ashur Y, Manns M, Naparstek Y: IgA deficiency associated with chronic hepatitis C virus infection. A cause or an effect? Arch Intern Med 1993; 153:1588-1592.
22. Knodell RG, Ishak KG, Black WC, Chen TS, Craig R, Kaplowitz N, Kiernan TW, Wollman J: Formulation and application of a numerical scoring system for assesing histologic activity in asymptomatic chronic active hepatitis. Hepatology 1981; 1:431-435.
23. Baptista A, Bianchi L, Desmet VJ, Gedigk P, Korb G, MacSween RNM, Popper H, Poulsen H, Scheuer PJ, Schmid M, Thaler H, Wepler W: Alcoholic liver disease: morphological manifestations. Review by an international group. Lancet 1981; 1:707-711.
24. Joliff CR, Cost KM, Stivrins PC, Grossman PP, Nolte CR, Franco SM, Fijan KJ, Fletcher LL, Shriner HC: Reference intervals for serum IgG, IgA, IgM, C3 and C4 as determined by rate nephelometry. Clin Chemistry 1982; 28:126-128.
25. Van de Wiel A, Delacroix DL, Van Hattum J, Schuurman HJ, Kater L: Characteristics of serum IgA and liver IgA deposits in alcoholic liver disease. Hepatology 1987; 7:95-99.
26. Kalsi J, Delacroix DL, Hodgson HJ: IgA in alcoholic cirrhosis. Clin Exp Immunol 1983; 52:499-504.
27. Delacroix DL, Reymaert M, Pauwels S, Geubel AP, Vaerman JP: High serum levels of secretory IgA in liver disease: possible liver origin of the circulating secretory component. Dig Dis Sci 1982; 27:333-340.
28. Seilles E, Rosell M, Vuitton DA, Mercier M, Mjoya O, Capron JP, Nalpas B, Gibey R, Revillard JP: Serum secretory IgA and secretory component in patients with non-cirrhotic alcoholic liver diseases. J Hepatol 1995; 22:278-285.
29. Meillet D, Labrousse F, Benoit MO, Hernvann A, Musset L, van Amerongen G: Increased serum IgA2 subclass and IgA2/IgA1 ratio: specific markers of chronic alcoholic abuse? Eur J Chem Clin Biochem 1997; 35:275-279.
30. Sopeña B, Martínez Vázquez C, de la Fuente J, Fernández C, Rivera A, Rodríguez MA, Rodríguez A: Serum levels of immunoglobulins and complement in alcoholic liver disease. Rev Clin Esp 1993; 193:419-423.
31. Parés A, Barrera JM, Caballería J, Ercilla G, Bruguera M, Caballería L, Castillo R, Rodes J: Hepatitis C virus in chronic alcoholic patients: association with severity of liver injury. Hepatology 1990; 12:1295-1299.
32. González-Quintela A, Alende R, Aguilera A, Tomé S, Gude F, Pérez Becerra E, Torre A, Martínez Vázquez JM, Barrio E: Anticuerpos frente al virus C de la hepatitis en alcoholicos activos. Rev Clin Esp 1995; 195:367-372.
33. Kruger TE, Jerrells TR: Effects of ethanol consumption and withdrawal on B cell subpopulations in murine bone marrow. Clin Exp Immunol 1994; 96:521-527.
34. Silvain C, Patry C, Launay P, Lehuen A, Monteiro RC: Altered expression of monocyte IgA Fc receptors is associated with defective endocytosis in patients with alcoholic cirrhosis. Potential role for IFN-gamma. J Immunol 1995; 155:1606-1618.
35. Van de Wiel A, Seifert WF, Van der Linden JA, Gmelig Myeling FH, Kater L, Schuurman HJ: Spontaneous IgA synthesis by blood mononuclear cells in alcoholic liver disease. Scand J Immunol 1987; 25:181-187.
36. Allison ME, Hodgson HJ: Regulation of peripheral blood B-cell IgA production in alcoholic cirrhosis. J Clin Lab Immunol 1989; 30:127-130.
37. Girón JA, Alvarez-Mon M, Menéndez-Caro JL, Abreu L, Albillos A, Manzano L, Durantez A: Increased spontaneous and lymphokine-conditioned IgA and IgG synthesis by B cells from alcoholic cirrhotic patients. Hepatology 1992; 16:664-670.
38. Maier A, Bode C, Fritz P, Bode JC: Effects of chronic alcohol abuse on duodenal mononuclear cells in man. Dig Dis Sci 1999; 44:691-696.
39. McClain CJ, Barve S, Deaciuc I, Kugelmas M, Hill D: Cytokines and alcoholic liver disease. Semin Liver Dis 1999; 19:205-219.
40. Deviere J, Content J, Denys C, Vandenbussche P, LeMoine O, Schandene L, Vaerman JP, Dupont E: Immunoglobulin A and interleukin 6 form a positive secretory feedback loop: a study of normal subjects and alcoholic cirrhotics. Gastroenterology 1992; 103:1296-1301.
41. Bac DJ, Pruimboom WM, Mulder PG, Zijlstra FJ, Wilson JH: High interleukin-6 production within the peritoneal cavity in decompensated cirrhosis and malignancy-related ascites. Liver 1995; 15:265-270.
42. González-Quintela A, Vidal C, Pérez LF, Lojo S, Otero E, Gude F, Barrio E: Serum cytokines and increased total serum IgE in alcoholics. Ann Allergy Asthma Immunol 1999; 83:61-67.
43. González-Quintela A, Alende MR, Lojo S, Pérez LF, Padín E, Tomé S, Vidal C: Total serum IgE in chronic hepatitis C. Influence of interferon-alpha therapy. Int Arch Allergy Immunol 2001; 125:176-181.
44. Pereira LF, Sapiña AM, Arroyo J, Viñuelas J, Bardají RM, Prieto L: Prevalence of selective IgA deficiency in Spain: more than we thought. Blood 1997; 90:893.
45. Webster ADB, Brown D, Franz A, Dusheiko G: Prevalence of hepatitis C in patients with primary antibody deficiency. Clin Exp Immunol 1996; 103:5-7.
46. Griffin DE: Immunologic abnormalities accompanying acute and chronic viral infections. Rev Infect Dis 1991; 13(Suppl 1):129-133.
47. Napoli J, Bishop A, McGuiness P, Painter D, McCaughan G: Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th-1-associated cytokines. Hepatology 1996; 24:759-765.
48. Reiser M, Mroussis CG, Nelson DR, Lauer G, González-Peralta RP, Davis GL, Lau JY: Serum interleukin 4 and interleukin 10 levels in patients with chronic hepatitis C virus infection. J Hepatol 1997; 26:471-478.
49. Tsai SL, Liaw YF, Chen MH, Huang CY, Kuo GC: Detection of type 2-like T-helper cells in hepatitis C virus infection: implications for hepatitis C virus chronicity. Hepatology 1997; 25:449-458.
50. Foschi FG, Gramenzi A, Castelli E, Cursaro C, Pagani S, Margotti M, C'Errico A, Andreone P, Stefanini GF, Bernardi M: Soluble CD30 serum level in HCV-positive chronic active hepatitis: a surrogate marker of disease activity? Cytokine 2000; 12:815-818.
51. Silvestri F, Pipan C, Barillari G, Zaja F, Fanin R, Infanti L, Russo D, Falasca E, Botta GA, Baccarani M: Prevalence of hepatitis C virus infection in patients with lymphoproliferative disorders. Blood 1996; 87:4296-4301.
52. De Rosa G, Gobbo ML, De Renzo A, Notaro R, Garofalo S, Grimaldi M, Apuzzo A, Chiurazzi F, Picardi M, Matarazzo M, Rotoli B: High prevalence of hepatitis C virus infection in patients with B-cell lymphoproliferative disorders in Italy. Am J Hematol 1997; 55:77-82.
53. Andreone P, Zignego AL, Cursaro C, Gramenzi A, Gherlinzoni F, Fiorino S, Giannini C, Boni P, Sabattini E, Pileri S, Tura S, Bernardi M: Prevalence of monoclonal gammopathies in patients with hepatitis C virus infection. Ann Intern Med 1998; 129:294-298.
54. Rasul I, Shepherd FA, Kamel-Reid S, Krajden M, Pantalony D, Heathcote EJ: Detection of low-grade B-cell non-Hodgkin's lymphoma in patients with chronic hepatitis C infection and mixed cryoglobulinemia. Hepatology 1999; 29:543-547.
55. Hausfauter P, Cacoub P, Rosenthal E, Bernard N, Loustaud-Ratti V, Le Lostec Z, Laurichesse H, Turpin F, Ouzan D, Grasset D, Perrone C, Cabrol MP, Piette JC: Hepatitis C virus infection and lymphoproliferative diseases in France: a national study. Am J Hematol 2000; 64:107-111.
56. Zignego AL, Gianelli F, Marrochi ME, Mazzocca A, Ferri C, Giannini C, Monti M, Caini P, Villa GL, Laffi G, Gentilini P: T(14;18) translocation in chronic hepatitis C virus infection. Hepatology 2000; 31:474-479.
57. Mangia A, Clemente R, Musto P, Cascavilla I, La Floresta P, Sanpaolo G, Gentile R, Vigliotti ML, Facciorusso D, Carotenuto M, Rizzetto M, Andriulli A: Hepatitis C virus infection and monoclonal gammopathies not associated with cryoglobulinemia. Leukemia 1996; 10:1209-1213.