Acute respiratory failure after interferon-γ therapy of end-stage pulmonary fibrosis

American Journal of Respiratory and Critical Care Medicine

Volumn 167, Issue 7, 2003, Pages 953-957

  Honoré, Isabelle ^b   Nunes, Hilario ^b   Groussard, Odile ^b   Kambouchner, Marianne ^b   Chambellan, Arnaud ^b   Aubier, Michel ^b   Valeyre, Dominique ^b   Crestani, Bruno ^a  

^a BICHAT HOSPITAL   (France)

^b NONE

Author keywords

Drug toxicity; Interferon type II; Lung diseases, interstitial

Indexed keywords

ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; AZATHIOPRINE; CARBON DIOXIDE; FUROSEMIDE; GAMMA INTERFERON 1B; METHYLPREDNISOLONE; PARACETAMOL; PREDNISOLONE; RECOMBINANT GAMMA INTERFERON; UNCLASSIFIED DRUG;

ACUTE RESPIRATORY FAILURE; ADULT; AGED; ARTICLE; BLOOD GAS ANALYSIS; CASE REPORT; CAUSE OF DEATH; CONTROLLED STUDY; DETERIORATION; DISEASE SEVERITY; DRUG INDUCED DISEASE; HUMAN; HYPOXEMIA; IMAGE ANALYSIS; INTERSTITIAL PNEUMONIA; LABORATORY TEST; LUNG ALVEOLUS; LUNG BIOPSY; LUNG CAPACITY; LUNG DIFFUSION CAPACITY; LUNG FIBROSIS; LUNG FUNCTION TEST; LUNG INJURY; LUNG TRANSPLANTATION; MALE; PREDICTION; PRIORITY JOURNAL; RADIODIAGNOSIS; THORAX RADIOGRAPHY; TREATMENT FAILURE;

ACUTE DISEASE; ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOCORTICOIDS; HUMANS; INTERFERON TYPE II; MALE; MIDDLE AGED; PULMONARY FIBROSIS; RESPIRATORY INSUFFICIENCY; TREATMENT FAILURE;

EID: 0344091556     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/rccm.200208-818CR     Document Type: Article

References (14)

1. International Consensus Statement. Idiopathic pulmonary fibrosis: diagnosis and treatment. Am J Respir Crit Care Med 2000;161:646-664.
2. Gurujeyalakshmi G, Giri SN. Molecular mechanisms of antifibrotic effect of interferon gamma in bleomycin-mouse model of lung fibrosis: down regulation of TGF-beta and procollagen I and III gene expression. Exp Lung Res 1995;21:791-808.
3. Ziesche R, Hofbauer E, Wittmann K, Petkov V, Block LH. A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis. N Engl J Med 1999;341:1264-1269.
4. Van Zandwijk N, Groen H, Postmus P, Burghouts J, Velde G, Ardizzoni A, Smith I, Baas P, Sahmoud T, Kirkpatrick A, et al. Role of recombinant interferon-gamma maintenance in responding patients with small cell lung cancer, a randomized phase III study. Eur J Cancer 1997;33:1759-1766.
5. Redman B, Flaherty L, Chou T, Al-Katid A, Kraut M, Martino S, Chen B, Kaplan J, Valdivieso M. A phase I trial of recombinant interferon-gamma combined with recombinant interleukin-2 in patients with cancer. J Clin Oncol 1990;8:1269-1276.
6. Shaw E, Deming R, Creagan E, Nair S, Su J, Levitt R, Steen P, Wiesenfeld M, Mailliard J. Pilot study of human recombinant interferon gamma and accelerated hyper fractionated thoracic radiation therapy in patients with unresectable stage IIIA/B nonsmall cell lung cancer. Int J Radiat Oncol Biol Phys 1995;31:827-831.
7. Honore I, Crestani B, Groussard O, Nunes H, Aubier M, Valeyre D. Aggravation aiguë de la fibrose pulmonaire idiopathique lors de l'initiation du traitement par interféron-gamma 1b. Rev Mal Respir 2002;19:128.
8. Kondoh Y, Taniguchi H, Kawabata Y, Yokoi T, Suzuki K, Takagi K. Acute exacerbations in idiopathic pulmonary fibrosis: analysis of clinical and pathologic findings in three cases. Chest 1993;103:1808-1812.
9. Akira M, Hamada H, Sakatani M, Kobayashi C, Nishioka M, Yamamoto S. CT findings during phase of accelerated deterioration in patients with idiopathic pulmonary fibrosis. AJR Am J Roentgenol 1997;168:79-83.
10. Yin K, Hock C, Lai P, Ross JT, Yue G. Role of interferon gamma in lung inflammation following cecal ligation and puncture in rats. Shock 1999;12:215-221.
11. Gudmundsson G, Hunninghake GW. Interferon-gamma is necessary for the expression of hypersensitivity pneumonitis. J Clin Invest 1997;99:2386-2390.
12. Seitz M, Franke M, Kirchner H. Induction of antinuclear antibodies in patients with rheumatoid arthritis receiving treatment with human recombinant interferon gamma. Ann Rheum Dis 1988;47:642-644.
13. Raghu G, Spada C, Otaki Y, Hayes J. Interferon gamma in the treatment of advanced idiopathic pulmonary fibrosis and fibrotic nonspecific interstitial pneumonia: prospective, preliminary clinical observations in one center. Chest 2001;120:185S.
14. Thomas AQ, Lane K, Phillips J III, Prince M, Markin C, Speer M, Schwartz DA, Gaddipati R, Marney A, Johnson J, et al. Heterozygosity for a surfactant protein C gene mutation associated with usual interstitial pneumonitis and cellular nonspecific interstitial pneumonitis in one kindred. Am J Respir Crit Care Med 2002;165:1322-1328.