Bisoprolol dose-response relationship in patients with congestive heart failure: A subgroup analysis in the cardiac insufficiency bisoprolol study (CIBIS II)

European Heart Journal

Volumn 24, Issue 6, 2003, Pages 552-559

  Simona, T ^a   Mary Krause, M ^b   Funck Brentano, C ^a   Lechat, Ph ^c   Jaillon, P ^a  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b INSERM   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Adrenergic beta antagonists; Congestive heart failure; Dose response relationship; Mortality

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISOPROLOL; PLACEBO;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; COMORBIDITY; CONGESTIVE HEART FAILURE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; FUNCTIONAL ASSESSMENT; HEART FAILURE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; PATIENT COMPLIANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK BENEFIT ANALYSIS; SURVIVAL RATE;

ADRENERGIC BETA-ANTAGONISTS; BISOPROLOL; DEATH, SUDDEN, CARDIAC; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HEART FAILURE, CONGESTIVE; HUMANS; MALE; MIDDLE AGED; RISK FACTORS; SURVIVAL ANALYSIS; TREATMENT OUTCOME; TREATMENT REFUSAL;

EID: 0344091552     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0195-668X(02)00743-1     Document Type: Article

References (17)

1. Remme WJ, Swedberg K. Guidelines for the diagnosis and treatment of chronic heart failure. Eur Heart J 2001; 22:1527-60.
2. Bristow MR. Beta-adrenergic receptor blockade in chronic heart failure. Circulation 2000; 101:558-69.
3. Cohn JN, Levin TB, Otivari MT et al. Plasma norepinephrine as a guide to prognosis in patients with chronic heart failure. N Engl J Med 1984; 311:819-23.
4. CIBIS II investigators and Committees. The Cardiac Insufficiency Bisoprotol Study II (CIBIS II): a randomized trial. Lancet 1999;353:9-13.
5. Bristow MR, O'Connell JB, Gilbert EM et al. Dose-response of chronic beta-blocker treatment in heart failure from either idiopathic dilated or ischemic cardiomyopathy. Bucindolol Investigators. Circulation 1994;89:1632-42.
6. Bristow MR, Gilbert EM, Adams KF et al. Carvedilol produces dose-related improvements in left ventricular function and survival in subjects with chronic heart failure. MOCHA Investigators. Circulation 1996;94:2807-16.
7. Eichhorn EJ, Bristow MR. Practical guidelines for initiation of beta-adrenergic blockade in patients with chronic heart failure. Am J Cardiol 1997;79:794-8.
8. MERIT-HF investigators. Effect of metoprolol CR/XL in chronic heart failure: metoprolol CR/XL randomized intervention trial in congestive heart failure. Lancet 1999; 353:2001-7.
9. Packer M, Bristow MR, Cohn JN et al. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. N Engl J Med 1996;334:1349-55.
10. CAPRICORN investigators. Effect of carvedilol on outcome after myocardial infarction in patients with left ventricular dysfunction. Lancet 2001;357:1385-90.
11. Packer M, Coats AJ, Fowler MB et al. Effect of carvedilol on survival in severe chronic heart failure. N Engl J Med 2001; 344:1651-8.
12. Swedberg K, Hjalmarson A, Waagstein F et al. Adverse effects of beta-blockade withdrawal in patients with congestive cardiomyopathy. Br Heart J 1980;44: 134-42.
13. Funck-Brentano C, Lancar R, Hansen S et al. Predictors of medical events and of their competitive interactions in the Cardiac Insufficiency Bisoprolol Study 2 (CIBIS-2). Am Heart J 2001;142:989-97.
14. Simon T, Mary-Krause M, Funck-Brentano C et al. Sex differences in the prognosis of congestive heart failure: results from the Cardiac Insufficiency Bisoprolol Study (CIBIS II). Circulation 2001;103:375-80.
15. Wiktrand D, Hjalmarson A, Waagstein F et al., MERIT-HF Study Group. Dose of metoprolol CR/XL and clinical outcomes in patients with heart failure: analysis of the experience in metoprolol CR/XL randomized intervention trial in chronic heart failure (MERIT/HF). J Am Coll Cardiol 2002; 40:491-8.
16. Nagatsu M, Spinale FG, Koide M et al. Bradycardia and the role of β-blockade in the amelioration of left ventricular dysfunction. Circulation 2000;101:653-9.
17. Lechat P, Hulot JS, Escolano S et al. Heart rate and cardiac rhythm relationships with bisoprolol benefit in chronic heart failure in CIBIS II trial. Circulation 2001;103:1428-33.