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Volumn 304, Issue 2, 2003, Pages 260-265

New phenothiazine-type multidrug resistance modifiers: Anti-MDR activity versus membrane perturbing potency

Author keywords

Drug lipid interactions; Lipid bilayer fluidity; Multidrug resistance reversal; P glycoprotein; Phenothiazine derivatives

Indexed keywords

GLYCOPROTEIN P; PHENOTHIAZINE DERIVATIVE;

EID: 0344088435     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00580-1     Document Type: Article
Times cited : (37)

References (39)
  • 1
    • 0033969525 scopus 로고    scopus 로고
    • Analysis of the tangled relationships between P-glycoprotein-mediated multidrug resistance and the lipid phase of the cell membrane
    • Ferte J. Analysis of the tangled relationships between P-glycoprotein-mediated multidrug resistance and the lipid phase of the cell membrane. Eur. J. Biochem. 267:2000;277-294.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 277-294
    • Ferte, J.1
  • 2
    • 0030577119 scopus 로고    scopus 로고
    • P-Glycoprotein multidrug resistance and cancer
    • Bosch I., Croop J. P-Glycoprotein multidrug resistance and cancer. Biochim. Biophys. Acta. 1288:1996;F37-F54.
    • (1996) Biochim. Biophys. Acta , vol.1288
    • Bosch, I.1    Croop, J.2
  • 3
    • 0034947674 scopus 로고    scopus 로고
    • From MDR to MXR: New understanding of multidrug resistance systems, their properties and clinical significance
    • Litman T., Druley T.E., Stein W.D., Bates S.E. From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell. Mol. Life Sci. 58:2001;931-959.
    • (2001) Cell. Mol. Life Sci. , vol.58 , pp. 931-959
    • Litman, T.1    Druley, T.E.2    Stein, W.D.3    Bates, S.E.4
  • 4
    • 0023898749 scopus 로고
    • Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells
    • Zamora J.M., Pearce H.L., Beck W.T. Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells. Mol. Pharmacol. 33:1988;454-462.
    • (1988) Mol. Pharmacol. , vol.33 , pp. 454-462
    • Zamora, J.M.1    Pearce, H.L.2    Beck, W.T.3
  • 5
    • 0030800078 scopus 로고    scopus 로고
    • Quantitative structure-activity relationship of multidrug resistance reversal agents
    • Klopman G., Shi L.M., Ramu A. Quantitative structure-activity relationship of multidrug resistance reversal agents. Mol. Pharmacol. 52:1997;323-334.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 323-334
    • Klopman, G.1    Shi, L.M.2    Ramu, A.3
  • 6
    • 0344761958 scopus 로고    scopus 로고
    • The importance of a nitrogen atom in modulators of multidrug resistance
    • Ecker G., Huber M., Schmid D., Chiba P. The importance of a nitrogen atom in modulators of multidrug resistance. Mol. Pharmacol. 56:1999;791-796.
    • (1999) Mol. Pharmacol. , vol.56 , pp. 791-796
    • Ecker, G.1    Huber, M.2    Schmid, D.3    Chiba, P.4
  • 7
    • 0032518454 scopus 로고    scopus 로고
    • A general pattern for substrate recognition by P-glycoprotein
    • Seelig A. A general pattern for substrate recognition by P-glycoprotein. Eur. J. Biochem. 251:1998;252-261.
    • (1998) Eur. J. Biochem. , vol.251 , pp. 252-261
    • Seelig, A.1
  • 8
    • 0033739115 scopus 로고    scopus 로고
    • Structure-activity relationship of P-glycoprotein substrates and modifiers
    • Seelig A., Landwojtowicz E. Structure-activity relationship of P-glycoprotein substrates and modifiers. Eur. J. Pharmaceut. Sci. 12:2000;31-40.
    • (2000) Eur. J. Pharmaceut. Sci. , vol.12 , pp. 31-40
    • Seelig, A.1    Landwojtowicz, E.2
  • 9
    • 0027743492 scopus 로고
    • The role of drug-lipid interactions in the biological activity of modulators of multi-drug resistance
    • Wadkins R.M., Houghton P.J. The role of drug-lipid interactions in the biological activity of modulators of multi-drug resistance. Biochim. Biophys. Acta. 1153:1993;225-236.
    • (1993) Biochim. Biophys. Acta , vol.1153 , pp. 225-236
    • Wadkins, R.M.1    Houghton, P.J.2
  • 11
    • 17544365536 scopus 로고    scopus 로고
    • The role of passive transbilayer drug movement in multidrug resistance and its modulation
    • Eytan G.D., Regev R., Oren G., Assaraf Y.G. The role of passive transbilayer drug movement in multidrug resistance and its modulation. J. Biol. Chem. 271:1996;12897-12902.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12897-12902
    • Eytan, G.D.1    Regev, R.2    Oren, G.3    Assaraf, Y.G.4
  • 12
    • 0020426820 scopus 로고
    • Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors
    • Tsuruo T., Iida H., Tsukagoshi S., Sakurai Y. Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors. Cancer Res. 42:1982;4730-4733.
    • (1982) Cancer Res. , vol.42 , pp. 4730-4733
    • Tsuruo, T.1    Iida, H.2    Tsukagoshi, S.3    Sakurai, Y.4
  • 13
    • 0031057694 scopus 로고    scopus 로고
    • Inhibition of the transport function of membrane proteins by some substituted phenothiazines in E. coli and multidrug resistant tumor cells
    • Molnár J., Hever A., Fakla I., Ocsovski I., Aszalos A. Inhibition of the transport function of membrane proteins by some substituted phenothiazines in E. coli and multidrug resistant tumor cells. Anticancer Res. 17:1997;481-486.
    • (1997) Anticancer Res. , vol.17 , pp. 481-486
    • Molnár, J.1    Hever, A.2    Fakla, I.3    Ocsovski, I.4    Aszalos, A.5
  • 15
    • 0017904125 scopus 로고
    • 31 P NMR studies on the interaction of some phenothiazine derivatives with dipalmitoyl phosphatidylcholine model membranes
    • 31 P NMR studies on the interaction of some phenothiazine derivatives with dipalmitoyl phosphatidylcholine model membranes Biochim. Biophys. Acta. 507:1978;185-197.
    • (1978) Biochim. Biophys. Acta , vol.507 , pp. 185-197
    • Frenzel, J.1    Arnold, K.2    Nuhn, P.3
  • 16
    • 0021943374 scopus 로고
    • Influence of cationic amphiphilic drugs on the phase-transition temperature of phospholipids with different polar headgroups
    • Hanpft R., Mohr K. Influence of cationic amphiphilic drugs on the phase-transition temperature of phospholipids with different polar headgroups. Biochim. Biophys. Acta. 814:1985;156-162.
    • (1985) Biochim. Biophys. Acta , vol.814 , pp. 156-162
    • Hanpft, R.1    Mohr, K.2
  • 17
    • 0344281094 scopus 로고    scopus 로고
    • Differences and similarities in the influence of trifluoperazine on the phase transitions of phosphatidylcholine and hosphatidylethanolamine
    • Hendrich A.B., Wesołowska O., Michalak K. Differences and similarities in the influence of trifluoperazine on the phase transitions of phosphatidylcholine and hosphatidylethanolamine. Curr. Topics Biophys. 25:2001;67-69.
    • (2001) Curr. Topics Biophys. , vol.25 , pp. 67-69
    • Hendrich, A.B.1    Wesołowska, O.2    Michalak, K.3
  • 18
    • 0345635413 scopus 로고    scopus 로고
    • Phenothiazine derivative causes phase separation in phosphatidylethanolamine model membranes
    • Wesołowska O., Hendrich A.B., Motohashi N., Michalak K. Phenothiazine derivative causes phase separation in phosphatidylethanolamine model membranes. Curr. Topics Biophys. 25:2001;71-73.
    • (2001) Curr. Topics Biophys. , vol.25 , pp. 71-73
    • Wesołowska, O.1    Hendrich, A.B.2    Motohashi, N.3    Michalak, K.4
  • 19
    • 0037008422 scopus 로고    scopus 로고
    • The alterations of lipid bilayer fluidity induced by newly synthesized phenothiazine derivative
    • Hendrich A.B., Wesołowska O., Komorowska M., Motohashi N., Michalak K. The alterations of lipid bilayer fluidity induced by newly synthesized phenothiazine derivative. Biophys. Chem. 98:2002;275-285.
    • (2002) Biophys. Chem. , vol.98 , pp. 275-285
    • Hendrich, A.B.1    Wesołowska, O.2    Komorowska, M.3    Motohashi, N.4    Michalak, K.5
  • 20
    • 0023277777 scopus 로고
    • Shape transformations induced by amphiphiles in erythrocytes
    • Isomaa B., Hägerstrand H., Paatero G. Shape transformations induced by amphiphiles in erythrocytes. Biochim. Biophys. Acta. 899:1987;93-103.
    • (1987) Biochim. Biophys. Acta , vol.899 , pp. 93-103
    • Isomaa, B.1    Hägerstrand, H.2    Paatero, G.3
  • 21
    • 0023687928 scopus 로고
    • Influence of chorpromazine on the transverse mobility of phospholipids in human erythrocyte membrane: Relation to shape changes
    • Rosso J., Zachowski A., Devaux P.F. Influence of chorpromazine on the transverse mobility of phospholipids in human erythrocyte membrane: relation to shape changes. Biochim. Biophys. Acta. 942:1988;271-279.
    • (1988) Biochim. Biophys. Acta , vol.942 , pp. 271-279
    • Rosso, J.1    Zachowski, A.2    Devaux, P.F.3
  • 22
    • 0032475507 scopus 로고    scopus 로고
    • Contribution of trifluoperazine/lipid ratio and drug ionization to hemolysis
    • Malheiros S.V., de Paula E., Meirelles N.C. Contribution of trifluoperazine/lipid ratio and drug ionization to hemolysis. Biochim. Biophys. Acta. 1373:1998;332-340.
    • (1998) Biochim. Biophys. Acta , vol.1373 , pp. 332-340
    • Malheiros, S.V.1    De Paula, E.2    Meirelles, N.C.3
  • 24
    • 0035830598 scopus 로고    scopus 로고
    • Trifluoperazine induces domain formation in zwitterionic phosphatidylcholine but not in charged phosphatidylglycerol bilayers
    • Hendrich A.B., Wesołowska O., Michalak K. Trifluoperazine induces domain formation in zwitterionic phosphatidylcholine but not in charged phosphatidylglycerol bilayers. Biochim. Biophys. Acta. 1510:2001;414-425.
    • (2001) Biochim. Biophys. Acta , vol.1510 , pp. 414-425
    • Hendrich, A.B.1    Wesołowska, O.2    Michalak, K.3
  • 25
    • 0024534226 scopus 로고
    • Structural features determining activity of phenothiazines and related drugs for inhibition of cell growth and reversal of multidrug resistance
    • Ford J.M., Prozialeck W.C., Hait W.N. Structural features determining activity of phenothiazines and related drugs for inhibition of cell growth and reversal of multidrug resistance. Mol. Pharmacol. 35:1989;105-115.
    • (1989) Mol. Pharmacol. , vol.35 , pp. 105-115
    • Ford, J.M.1    Prozialeck, W.C.2    Hait, W.N.3
  • 26
    • 0026624915 scopus 로고
    • Reversal of multidrug resistance by phenothiazines and structurally related compounds
    • Ramu A., Ramu N. Reversal of multidrug resistance by phenothiazines and structurally related compounds. Cancer Chemother. Pharmacol. 30:1992;165-173.
    • (1992) Cancer Chemother. Pharmacol. , vol.30 , pp. 165-173
    • Ramu, A.1    Ramu, N.2
  • 27
    • 0029655680 scopus 로고    scopus 로고
    • Membrane interactions of some catamphilic drugs and relation to their multidrug-resistance-reversing ability
    • Pajeva I.K., Wiese M., Cordes H.P., Seydel J.K. Membrane interactions of some catamphilic drugs and relation to their multidrug-resistance-reversing ability. J. Cancer Res. Clin. Oncol. 122:1996;27-40.
    • (1996) J. Cancer Res. Clin. Oncol. , vol.122 , pp. 27-40
    • Pajeva, I.K.1    Wiese, M.2    Cordes, H.P.3    Seydel, J.K.4
  • 28
    • 0030898431 scopus 로고    scopus 로고
    • QSAR and molecular modelling of catamphilic drugs able to modulate multidrug resistance in tumors
    • Pajeva I.K., Wiese M. QSAR and molecular modelling of catamphilic drugs able to modulate multidrug resistance in tumors. Quant. Struct.-Act. Relat. 16:1997;1-10.
    • (1997) Quant. Struct.-Act. Relat. , vol.16 , pp. 1-10
    • Pajeva, I.K.1    Wiese, M.2
  • 31
    • 84911792416 scopus 로고
    • Atomic physicochemical parameters for three dimensional structure activity relationships III: Modelling hydrophobic interactions
    • Ghose A.K., Pritchett A., Crippen G.M. Atomic physicochemical parameters for three dimensional structure activity relationships III: modelling hydrophobic interactions. J. Comput. Chem. 9:1988;80-90.
    • (1988) J. Comput. Chem. , vol.9 , pp. 80-90
    • Ghose, A.K.1    Pritchett, A.2    Crippen, G.M.3
  • 33
    • 0030795841 scopus 로고    scopus 로고
    • Characterization of functional assays of multidrug resistance P-glycoprotein transport activity
    • Bosch I., Crankshaw C.L., Piwnica-Worms D., Croop J.M. Characterization of functional assays of multidrug resistance P-glycoprotein transport activity. Leukemia. 11:1997;1131-1137.
    • (1997) Leukemia , vol.11 , pp. 1131-1137
    • Bosch, I.1    Crankshaw, C.L.2    Piwnica-Worms, D.3    Croop, J.M.4
  • 34
    • 0013508682 scopus 로고
    • A retrovirus carrying an MDR-1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells
    • Pastan I., Gottesman M.M., Ueda K., Lovelace E., Rutheford A.V., Willingham M.C. A retrovirus carrying an MDR-1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. Proc. Natl Acad. Sci. USA. 85:1988;4486-4490.
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 4486-4490
    • Pastan, I.1    Gottesman, M.M.2    Ueda, K.3    Lovelace, E.4    Rutheford, A.V.5    Willingham, M.C.6
  • 35
    • 0027195754 scopus 로고
    • The effect of ion channel blockers, immunosupressive agents, and other drugs on the activity of the multi-drug transporter
    • Weaver J.L., Szabo G., Pine P.S., Gottesman M.M., Goldenberg S., Aszalos A. The effect of ion channel blockers, immunosupressive agents, and other drugs on the activity of the multi-drug transporter. Int. J. Cancer. 54:1993;456-461.
    • (1993) Int. J. Cancer , vol.54 , pp. 456-461
    • Weaver, J.L.1    Szabo, G.2    Pine, P.S.3    Gottesman, M.M.4    Goldenberg, S.5    Aszalos, A.6
  • 36
    • 0032474434 scopus 로고    scopus 로고
    • Location of diphenylhexatriene (DPH) and its derivatives within membranes: Comparison of different fluorescence quenching analyses of membrane depth
    • Kaiser R.D., London E. Location of diphenylhexatriene (DPH) and its derivatives within membranes: comparison of different fluorescence quenching analyses of membrane depth. Biochemistry. 37:1998;8180-8190.
    • (1998) Biochemistry , vol.37 , pp. 8180-8190
    • Kaiser, R.D.1    London, E.2
  • 37
    • 0019886347 scopus 로고
    • Emission-wavelength-dependent decay of the fluorescent probe N-phenyl-1-naphthylamine
    • Matayoshi E.D., Kleinfeld A.M. Emission-wavelength-dependent decay of the fluorescent probe N-phenyl-1-naphthylamine. Biochim. Biophys. Acta. 644:1981;233-243.
    • (1981) Biochim. Biophys. Acta , vol.644 , pp. 233-243
    • Matayoshi, E.D.1    Kleinfeld, A.M.2
  • 38
    • 0029840320 scopus 로고    scopus 로고
    • Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains
    • Liu R., Sharom F.J. Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains. Biochemistry. 35:1996;11865-11873.
    • (1996) Biochemistry , vol.35 , pp. 11865-11873
    • Liu, R.1    Sharom, F.J.2
  • 39
    • 0034610402 scopus 로고    scopus 로고
    • Intrinsic fluorescence of the P-glycoprotein multidrug transporter: Sensitivity of tryptophan residues to binding of drugs and nucleotides
    • Liu R., Siemiarczuk A., Sharom F.J. Intrinsic fluorescence of the P-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides. Biochemistry. 39:2000;14927-14938.
    • (2000) Biochemistry , vol.39 , pp. 14927-14938
    • Liu, R.1    Siemiarczuk, A.2    Sharom, F.J.3


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