Interleukin-2 Abolishes Myeloid Cell Accumulation Induced by Lewis Lung Carcinoma

Journal of Interferon and Cytokine Research

Volumn 23, Issue 11, 2003, Pages 631-638

  Shin Ya, Masaharu ^a,b   Mazda, Osam ^b   Tsuchihara, Chiharu ^a   Hirai, Hideyo ^b   Imanishi, Jiro ^b   Takeuchi, Minoru ^a  

^a KYOTO SANGYO UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; B7 ANTIGEN; CD11B ANTIGEN; CONCANAVALIN A; GRA 1 ANTIGEN; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NK K1 ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BIOENGINEERING; BONE MARROW CELL; CANCER CELL; CANCER TRANSPLANTATION; CELL ACTIVITY; CELL COUNT; CELL POPULATION; CELL PROLIFERATION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FLOW CYTOMETRY; IN VIVO STUDY; LEWIS CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; SPLEEN CELL; SPLENOMEGALY; T LYMPHOCYTE; TUMOR GROWTH;

ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; CONCANAVALIN A; FEMALE; FLOW CYTOMETRY; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MYELOID CELLS; NEOPLASM TRANSPLANTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

ANIMALIA;

EID: 0344010952     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999003322558764     Document Type: Article

References (37)

1. ALMAND, B., RESSER, J.R., LINDMAN, B., NADAF, S., CLARK, J.I., KWON, E.D., CARBONE, D.P., and GABRILOVICH, D.I. (2000). Clinical significance of defective dendritic cell differentiation in cancer. Clin. Cancer Res. 6, 1755-1766.
2. BRONTE, V., SERAFINI, P., APOLLONI, E., and ZANOVELLO, P. (2001). Tumor-induced immune dysfunctions caused by myeloid suppressor cells. J. Immunother. 24, 431-446.
3. KUSMARTSEV, S., and GABRILOVICH, D.I. (2002). Immature myeloid cells and cancer-associated immune suppression. Cancer Immunol. Immunother. 51, 293-298.
4. + T cell responses by dysregulating antigen-presenting cell maturation. J. Immunol. 162, 5728-5737.
5. ALMAND, B., CLARK, J.I., NIKITINA, E., VAN BEYNEN, J., ENGLISH, N.R., KNIGHT, S.C., CARBONE, D.P., and GABRILOVICH, D.I. (2001). Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J. Immunol. 166, 678-689.
6. + myeloid cells. J. Immunol. 166, 5398-5406.
7. CAULEY, L.S., MILLER, E.E., YEN, M., and SWAIN, S.L. (2000). Superantigen-induced CD4 T cell tolerance mediated by myeloid cells and IFN-gamma. J. Immunol. 165, 6056-6066.
8. DALTON, D.K., HAYNES, L., CHU, C.Q., SWAIN, S.L., and WITTMER, S. (2000). Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J. Exp. Med. 192, 117-122.
9. (+) T cell proliferation via an IFN-gamma and nitric oxide-dependent mechanism. J. Immunol. 167, 4293-4302.
10. FU, Y.X., WATSON, G., JIMENEZ, J.J., WANG, Y., and LOPEZ, D.M. (1990). Expansion of immunoregulatory macrophages by granulocyte-macrophage colony-stimulating factor derived from a murine mammary tumor. Cancer Res. 50, 227-234.
11. 2-dependent and -independent immune suppressor cells by tumor-derived GM-CSF and M-CSF. J. Leukocyte Biol. 53, 86-92.
12. YOUNG, M.R., WRIGHT, M.A., MATTHEWS, J.P., MALIK, I., and PRECHEL, M. (1996). Suppression of T cell proliferation by tumor-induced granulocyte-macrophage progenitor cells producing transforming growth factor-beta and nitric oxide. J. Immunol. 156, 1916-1922.
13. (+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor. Blood 92, 4778-4791.
14. SAITO, H., TSUJITANI, S., IKEGUCHI, M., MAETA, M., and KAIBARA, N. (1998). Relationship between the expression of vascular endothelial growth factor and the density of dendritic cells in gastric adenocarcinoma tissue. Br. J. Cancer 78, 1573-1577.
15. GABRILOVICH, D.I., CHEN, H.I., GIRGIS, K.R., CUNNINGHAM, H.T., MENY, G.M., NADAF, S., KAVANAUGH, D., and CARBONE, D.P. (1996). Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat. Med. 2, 1096-1103.
16. ROSENBERG, S.A. (2001). Progress in the development of immunotherapy for the treatment of patients with cancer. J. Intern. Med. 250, 462-475.
17. + myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation. J. Immunol. 165, 779-785.
18. WATSON, G.A., FU, Y.X., and LOPEZ, D.M. (1991). Splenic macrophages from tumor-bearing mice co-expressing MAC-1 and MAC-2 antigens exert immunoregulatory functions via two distinct mechanisms. J. Leukocyte Biol. 49, 126-138.
19. ATKINS, M.B. (2002). Interleukin-2: clinical applications. Semin. Oncol. 29, 12-17.
20. ROSENBERG, S.A. (2001). Progress in human tumour immunology and immunotherapy. Nature 411, 380-384.
21. BERTRAM, J.S., and JANIK, P. (1980). Establishment of a cloned line of Lewis lung carcinoma cells adapted to cell culture. Cancer Lett. 11, 63-73.
22. MAZDA, O., SATOH, E., YASUTOMI, K., and IMANISHI, J. (1997). Extremely efficient gene transfection into lympho-hematopoietic cel lines by Epstein-Barr virus-based vectors. J. Immunol. Methods 204, 143-151.
23. + cells within human head and neck squamous cell carcinomas. J. Immunol. 159, 990-996.
24. YOUNG, M.R., and NEWBY, M. (1986). Differential induction of suppressor macrophages by cloned Lewis lung carcinoma variants in mice. J. Natl. Cancer Inst. 77, 1255-1260.
25. KUSMARTSEV, S., RUIZ DE MORALES, J.M., RULLAS, J., DANILETS, M.G., and SUBIZA, J.L. (1999). Sialoadhesin expression by bone marrow macrophages derived from Ehrlich tumor-bearing mice. Cancer Immunol. Immunother. 48, 493-398.
26. SUBIZA, J.L., VINUELA, J.E., RODRIGUEZ, R., GIL, J., FIGUEREDO, M.A., and DE LA CONCHA, E.G. (1989). Development of splenic natural suppressor (NS) cells in Ehrlich tumor-bearing mice. Int. J. Cancer 44, 307-314.
27. ALLEVA, D.G., WALKER, T.M., and ELGERT, K.D. (1995). Induction of macrophage suppressor activity by fibrosarcoma-derived transforming growth factor-beata 1: contrasting effects on resting and activated macrophages. J. Leukocyte Biol. 57, 919-928.
28. JAFFEE, E.M., THOMAS, M.C., HUANG, A.Y., HAUDA, K.M., LEVITSKY, H.I., and PARDOLL, D.M. (1996). Enhanced immune priming with spatial distribution of paracrine cytokine vaccines. J. Immunother. Emphasis Tumor Immunol. 19, 176-183.
29. OTSUJI, M., KIMURA, Y., AOE, T., OKAMOTO, Y., and SAITO, T. (1996). Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses. Proc. Natl. Acad. Sci. USA 93, 13119-13124.
30. YOUNG, M.R., NEWBY, M., and WEPSIC, H.T. (1987). Hematopoiesis and suppressor bone marrow cells in mice bearing large metastatic Lewis lung carcinoma tumors. Cancer Res. 47, 100-105.
31. ANGULO, I., RODRIGUEZ, R., GARCIA, B., MEDINA, M., NAVARRO, J., and SUBIZA, J.L. (1995). Involvement of nitric oxide in bone marrow-derived natural suppressor activity. Its dependence on IFN-gamma. J. Immunol. 155, 15-26.
32. FIELDS, P., FITCH, F.W., and GAJEWSKI, T.F. (1996). Control of T lymphocyte signal transduction through clonal anergy. J. Mol. Med. 74, 673-683.
33. APPLEMAN, L.J., TZACHANIS, D., GRADER-BECK, T., VAN PUIJENBROEK, A.A., and BOUSSIOTIS, V.A. (2001). Helper T cell anergy: from biochemistry to cancer pathophysiology and therapeutics. J. Mol. Med. 78, 673-683.
34. SCUDELETTI, M., FILACI, G., IMRO, M.A., MOTTA, G., DI GAETANO, M., PIERRI, I., TONGIANI, S., INDIVERI, F., and PUPPO, F. (1993). Immunotherapy with intralesional and systemic interleukin-2 of patients with non-small cell lung cancer. Cancer Immunol. Immunother. 37, 119-124.
35. EMTAGE, P.C., WAN, Y., MULLER, W., GRAHAM, F.L., and GAULDIE, J. (1998). Enhanced interleukin-2 gene transfer immunotherapy of breast cancer by coexpression of B7-1 and B7-2. J. Interferon Cytokine Res. 18, 927-937.
36. MAZDA, O., SATOH, E., HIRAI, H., NOMURA. M., and IMANISHI, J. (2000). Non-viral strategies for immuno-gene therapy. In: Recent Research Developments in Immunology. M.P. Cancro (ed.) Trivandrum, IN: Research Signpost, pp. 273-281.
37. MAZDA, O. (2002). Improvement of nonviral gene therapy by Epstein-Barr virus (EBV)-based plasmid vectors. Curr. Gene Ther. 2, 379-392.