Regulation of protein synthesis by minigene expression

Biochimie

Volumn 79, Issue 8, 1997, Pages 527-531

  Hernandez J ^a   Ontiveros, C ^a   Valadez, J G ^a   Buckingham, R H ^b   Guarneros, G ^a,c  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b INST DE BIOLOGIE PHYSICO CHIMIQUE   (France)

^c INSTITUTO DE CIENCIAS FÍSICAS   (Mexico)

Author keywords

Bacteriophage lambda bar regions; Minigenes; Peptidyl tRNA hydrolase; Protein synthesis inhibition; tRNA starvation

Indexed keywords

HYDROLASE; PEPTIDYL TRNA HYDROLASE; POLYPEPTIDE; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; BACTERIOPHAGE LAMBDA; CELL VIABILITY; CODON; CONTROLLED STUDY; ESCHERICHIA COLI; GENE EXPRESSION; GENE MUTATION; MINIGENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN SYNTHESIS REGULATION; STOP CODON;

EID: 0343990004     PISSN: 03009084     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-9084(97)82746-0     Document Type: Article

References (24)

1. Menninger JR, Mulholland MC, Stirewalt WS (1970) Pep-tRNA hydrolase and protein chain termination. Biochim Biophys Acta 227, 496-511
2. Atherly AG, Menninger JR (1972) Mutant E coli strain with temperature sensitive peptydyl-transfer RNA hydrolase. Nature New Biol 240, 245-246
3. Menninger JR (1976) Peptidyl transfer RNA dissociates during protein synthesis from ribosomes of Escherichia coli. J Biol Chem 25, 3392-3398
4. García-Villegas MR, De la Vega FM, Galindo JM, Segura M, Buckingham RH, Guarneros G (1991) Peptidyl-tRNA hydrolase is involved in λ inhibition of host protein synthesis. EMBO J 10, 3549-3555
5. Dutka S, Meinnel T, Lazennec C, Mechulam Y, Blanquet S (1993) Role of the 1-72 base pair in tRNAs for the activity of Escherichia coli peptidyl-tRNA hydrolase. Nucleic Acids Res 21, 4025-4030
6. Schmitt E, Mechulam Y, Fromant M, Plateau P, Blanquet S (1997) Crystal structure at 1.2 Å resolution and active site mapping of Escherichia coli peptidyl-tRNA hydrolase. EMBO J 16, 4760-4769
7. Brun G, Paulin D, Yot P, Chapeville F (1971) Peptidyl tRNA hydrolase: Mise en évidence dans différents organismes. Activité enzymatique en présence des ribosomes. Biochimie 53, 225-231
8. De la Vega FM, Galindo JM, Old IG, Guarneros G (1996) Microbial genes homologous to peptidyl-tRNA hydrolase-encoding gene of Escherichia coli. Gene 169, 97-100
9. Lys. EMBO J 11, 2826-2833
10. Henderson D, Weil J (1976) A mutant of Escherichia coli that prevents growth of phage lambda and is bypassed by lambda mutants in a nonessential region of the genome. Virology 71, 546-559
11. Guzmán P, Guarneros G (1989) Phage genetic sites involved in λ growth inhibition by the Escherichia coli rap mutant. Genetics 121, 401-410
12. Guzmán P, Rivera BE, Court DL, Gottesman ME, Guarneros G (1990) Transcription of a bacteriophage λ DNA site blocks growth of Escherichia coli. J Bacteriol 172, 1030-1034
13. Pérez-Morga D, Guarneros G (1990) A short DNA sequence from phage λ inhibits protein synthesis in Escherichia coli. J Mol Biol 172, 243-250
14. Murgola EJ, Guarneros G (1991) Ribosomal RNA and peptidyl-tRNA hydrolase: a peptide chain termination model for lambda bar RNA inhibition. Biochimie 73, 1573-1578
15. Ontiveros C, Valadez JG, Hernández J, Guarneros G (1997) Inhibition of Escherichia coli protein synthesis by abortive translation of phage λ minigenes. J Mol Biol 269, 167-175
16. Nierhaus KH, Witttmann HG (1980) Ribosomal function and its inhibition by antibiotics in prokaryotes. Naturwissenschafften 67, 234-250
17. Ikemura T (1981) Correlation between the abundance of Escherichia coli transfer RNAs and the occurrence of the respective codons in its protein genes. J Mol Biol 146, 1-21
18. Dong H, Nilsson L, Kurland CG, (1996) Co-variation of tRNA abundance and codon usage in Escherichia coli at different growth rates. J Mol Biol 260, 649-663
19. Menninger JR, Walker C, Tan PF, Atherly AG (1973) Studies on the metabolic role of peptidyl-tRNA hydrolase: II. Properties of a mutant E coli with a temperature-sensitive peptidyl-tRNA hydrolase. Mol Gen Genet 121, 307-324
20. Yanofsky C (1981) Attenuation in the control of expression of bacterial operons. Nature 289, 751-758
21. Weisblum B (1983) In: Gene Function in Prokaryotes (Beckwith J, Davies J, Gallant JA, eds) Cold Spring Harbor Laboratory, NY, 91-121
22. Lovett PS (1990) Translational attenuation as the regulator of inducible cat genes. J Bacteriol 172, 1-6
23. Gu Z, Harrod R, Rogers EJ, Lovett PS (1994) Properties of a pentapeptide inhibitor of peptidyl-transferase that is essential for cat gene regulation by translation attenuation. J Bacteriol 176, 6238-6244
24. Tenson T, DeBlasio A, Mankin A (1996) A functional peptide encoded in the Escherichia coli 23S rRNA. Proc Natl Acad Sci USA 93, 5641-5646