RLR1 (THO2), required for expressing lacZ fusions in yeast, is conserved from yeast to humans and is a suppressor of SIN4

Gene

Volumn 243, Issue 1-2, 2000, Pages 195-205

  West Jr , Robert W ^a   Kruger, Brian ^a   Thomas, Sean ^a   Ma, Junli ^a   Milgrom, Elena ^a  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

Chromatin; KEKE motif; lacZ; Mediator; Transcription

Indexed keywords

HYBRID PROTEIN;

ARTICLE; CAENORHABDITIS ELEGANS; CHROMATIN STRUCTURE; DNA SEQUENCE; GENE DISRUPTION; GENE FUSION; GENE MAPPING; GENE MUTATION; GENETIC PROCEDURES; GENETIC TRANSCRIPTION; NONHUMAN; PLASMID; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION;

AMINO ACID SEQUENCE; CELL DIVISION; CLONING, MOLECULAR; CONSERVED SEQUENCE; CYTOCHROME C GROUP; CYTOCHROMES C; DNA, FUNGAL; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; HUMANS; LAC OPERON; MOLECULAR SEQUENCE DATA; MUTATION; PHYLOGENY; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SPORES, FUNGAL; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0343750688     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00510-7     Document Type: Article

References (27)

1. Appel R.D., Bairoch A., Hochstrasser D.F. A new generation of information retrieval tools for biologists: the example of the ExPASy WWW server. Trends Biochem. Sci. 19:1994;258-260.
2. Chavez S., Aguilera A. The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability. Genes Dev. 11:1997;3459-3470.
3. Chen S., West R.W. Jr., Ma J., Johnson S.L., Gans H., Woldehawariat G. TSF1 to TSF6, required for silencing the Saccharomyces cerevisiae GAL genes, are global regulatory genes. Genetics. 134:1993;701-716.
4. Chen S., West R.W. Jr., Johnson S.L., Gans H., Kruger B., Ma J. TSF3, a global regulatory protein that silences transcription of yeast GAL genes, also mediates repression by α2 repressor and is identical to SIN4. Mol. Cell. Biol. 13:1993;831-840.
5. Fan H.-Y., Cheng K.K., Klein H.L. Mutations in the RNA polymerase II transcription machinery suppress the hyperrecombination mutant hpr1Δ of Saccharomyces cerevisiae. Genetics. 142:1996;749-759.
6. G control transcription of the yeast GAL genes. Mol. Cell. Biol. 10:1990;5663-5670.
7. Garnier J., Gibrat J.-F., Robson B. GOR secondary structure prediction method version IV. Methods Enzymol. 266:1996;540-553.
8. Gietz D.R., Woods R.A. High efficiency transformation with lithium acetate. Johnston J.R. Molecular Genetics of Yeast: A Practical Approach. 1994;IRL Press, New York.
9. Harashima S., Mizuno T., Mabuchi H., Yoshimitsu S., Ramesh R., Hasebe M., Tanaka A., Oshima Y. Mutations causing high basal level transcription that is independent of transcriptional activators but dependent on chromosomal position in Saccharomyces cerevisiae. Mol. Gen. Genet. 247:1995;716-725.
10. Holstege F.C., Young R.A. Transcriptional regulation: contending with complexity. Proc. Natl. Acad. Sci. USA. 96:1999;2-4.
11. Jiang Y.W., Stillman D.J. Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisae. Mol. Cell. Biol. 12:1992;4503-4514.
12. Macatee T., Jiang Y.J., Stillman D.J., Roth S.Y. Global alterations in chromatin accessibility associated with loss of SIN4 function. Nucleic Acids Res. 25:1997;1240-1247.
13. Marck C. A "C" program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers. Nucleic Acids Res. 16:1988;1829-1836.
14. Muñoz V., Serrano L. Development of the Multiple Sequence Approximation within the Agadir model of α-helix formation. Comparison with Zimm-Bragg and Lifson-Roig Formalisms. Biopolymers. 41:1997;495-509.
15. Myers L.C., Gustafsson C.M., Hayashibara K.C., Brown P.O., Kornberg R.D. Mediator protein mutations that selectively abolish activated transcription. Proc. Natl. Acad. Sci. USA. 96:1999;67-72.
16. Nakai K., Horton P. PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem. 24:1999;34-35.
17. Nelson J.R., Ziegelhoffer T., Nicolet C., Werner-Washburn M., Craig E.A. The translational machinery and 70 kd heat shock protein cooperate in protein synthesis. Cell. 7:1992;97-105.
18. Piruat J.I., Aguilera A. A novel yeast gene, THO2, is involved in RNA polymerase II transcription and provides new evidence for transcriptional elongation-associated recombination. EMBO J. 17:1998;4859-4872.
19. Realini C., Rogers S.W., Rechsteiner M. KEKE motifs: proposed roles in protein-protein association and presentation of peptides by MHC Class I receptors. FEBS Lett. 348:1994;109-113.
20. Realini C., Dubiel W., Pratt G., Ferrell K., Rechsteiner M. Molecular cloning and expression of a gamma-interferon-inducible activator of the multicatalytic protease. J. Biol. Chem. 269:1994;20727-20732.
21. Rost B. PhD: predicting one-dimensional protein structure by profile based neural networks. Methods Enzymol. 266:1996;525-539.
22. Tabtiang R.K., Herskowitz I. Nuclear proteins Nut1p and Nut2p cooperate to negatively regulate a Swi4p-dependent lacZ reporter gene in Saccharomyces cerevisiae. Mol. Cell. Biol. 18:1998;4707-4718.
23. Thompson J.D., Higgins D.G., Gibson T.J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:1994;4673-4680.
24. G. Mol. Cell. Biol. 4:1984;2467-2478.
25. Yocum R.R., Hanley S., West R.W. Jr., Ptashne M. Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol. Cell. Biol. 4:1984;1985-1998.
26. Zhang Z., Realini C., Clawson A., Endicott S., Rechsteine M. Proteasome activation by REG molecules lacking homolog-specific inserts. J. Biol. Chem. 273:1998;9501-9509.
27. Zhu Y., Peterson C., Christman M.F. HPR1 encodes a global positive regulator of transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 15:1995;1698-1708.